Job Description P27240 Confidence 99.78% Date Thu Jan 5 11:43:19 GMT 2012 Rank 164 Aligned Residues 176 % Identity 17% Template c3eygA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 1.90 Å

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		25	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.							.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.
Predicted Secondary structure																															.	.	.	.	.	.
Query SS confidence																															.	.	.	.	.	.
Query Sequence		L	N	D	F	L	S	Y	N	I	N	I	I	K	V	F	R	S	I	D	D	T	K	V	M	L	I	D	T	D	.	.	.	.	.	.	Y	G	K	L	I	L	K	V	F	S	P	K	V	K	R	N	E	R	F	F	K	S	L	L	K	G	D	Y	Y	E	R	L	F	E	Q	T	Q	K	V	R	N	E	G	L	N
Query Conservation																															.	.	.	.	.	.
Alig confidence																															.	.	.	.	.	.														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		P	T	H	F	E	K	R	F	L	K	R	I	R	D	L	G	E	G	H	F	G	K	V	E	L	C	R	Y	D	P	E	G	D	N	T	G	E	Q	V	A	V	K	S	L	K	P	H	I	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	D	L	K	K	E	I	E	I	L	R
Template Known Secondary structure		T	T	S			G	G	G											S	S										T	T	S	S	S		S													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		867	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.																						.	.	.	.	.	920	.	.	.	.	.
		99	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.										.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																					.	.	.	.	.	.	.	.	.
Query SS confidence																																					.	.	.	.	.	.	.	.	.
Query Sequence		T	L	N	D	F	Y	L	L	A	E	R	K	T	L	R	F	V	H	T	Y	I	M	I	I	E	Y	I	D	G	I	E	L	C	D	M	.	.	.	.	.	.	.	.	.	P	D	I	D	D	A	L	K	N	K	I	Q	Q	S	I	N	A	L	H	Q	H	G	M	V	S	G	D	P	H	R	G	N	F	I	I	K
Query Conservation																																					.	.	.	.	.	.	.	.	.
Alig confidence														.																							.	.	.	.	.	.	.	.	.
Template Conservation														.
Template Sequence		N	L	Y	H	E	N	I	V	K	Y	K	G	.	I	C	T	E	N	G	I	K	L	I	M	E	F	L	P	S	G	S	L	K	E	Y	L	P	K	N	K	N	K	I	N	L	K	Q	Q	L	K	Y	A	V	Q	I	C	K	G	M	D	Y	L	G	S	R	Q	Y	V	H	R	D	L	A	A	R	N	V	L	V	E
Template Known Secondary structure		T				T	T	B						.															T	T		B					T	G	G	G	T	T	T																							T	T				S			S	G	G	G
Template Predicted Secondary structure														.
Template SS confidence
		931	.	.	.	.	.	.	.	.	940	.	.		.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.
			170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.														.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
Predicted Secondary structure		.																														.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.																														.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	N	G	E	V	R	I	I	D	L	S	G	K	R	A	S	A	Q	R	K	A	K	D	R	I	D	L	E	R	H	.	.	.	.	.	.	.	.	.	.	.	.	.	Y	G	I	K	N	E	I	R	D	L	G	Y	Y	L	L	V	Y	R	K	K	M	R	N	F
Query Conservation		.																														.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.																														.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		S	E	H	Q	V	K	I	G	D	F	G	L	T	K	A	I	E	T	D	K	E	T	V	K	D	D	R	D	S	P	V	F	W	Y	A	P	E	C	L	M	Q	S	K	F	Y	I	A	S	D	V	W	S	F	G	V	T	L	H	E	L	L	T	Y	C	D	S	D
Template Known Secondary structure			T	T								T	T						T	T					S			T	T			G	G	G																													T	T	T		G	G
Template Predicted Secondary structure
Template SS confidence
		1013	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions