Job Description P27240 Confidence 99.73% Date Thu Jan 5 11:43:19 GMT 2012 Rank 178 Aligned Residues 177 % Identity 14% Template c1xkkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016 Resolution 2.40 Å

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		28	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	L	S	Y	N	I	N	I	I	K	V	F	R	S	I	D	D	T	K	V	M	L	I	D	T	D	Y	G	K	L	I	L	K	V	F	S	P	K	V	K	R	N	E	R	F	F	K	S	L	L	K	G	D	Y	Y	E	R	L	F	E	Q	T	Q	K	V	R	N	E	G	L	N	T	L	N	D	F	Y	L	L	A
Query Conservation
Alig confidence																																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	K	E	T	E	F	K	K	I	K	V	L	G	S	G	A	F	G	T	V	Y	K	G	L	W	I	P	V	K	I	P	V	A	I	K	E	L	R	E	K	A	N	K	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	L	D	E	A	Y	V	M	A	S	V	D	N	P	H	V	C	R
Template Known Secondary structure				T	T	T											S	S																								T				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														T	T	B
Template Predicted Secondary structure																																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		707	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750																			.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.
		108	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.									.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.		170	.	.	.	.	.	.	.	.
Predicted Secondary structure																						.	.	.	.	.	.	.	.																																											.
Query SS confidence																						.	.	.	.	.	.	.	.																																											.
Query Sequence		E	R	K	T	L	R	F	V	H	T	Y	I	M	I	I	E	Y	I	D	G	.	.	.	.	.	.	.	.	I	E	L	C	D	M	P	D	I	D	D	A	L	K	N	K	I	Q	Q	S	I	N	A	L	H	Q	H	G	M	V	S	G	D	P	H	R	G	N	F	I	I	K	.	N	G	E	V	R	I	I	D	L
Query Conservation																						.	.	.	.	.	.	.	.																																											.
Alig confidence																						.	.	.	.	.	.	.	.																																											.
Template Conservation
Template Sequence		L	L	G	I	C	L	T	S	T	V	Q	L	I	T	Q	L	M	P	F	G	C	L	L	D	Y	V	R	E	H	K	D	N	I	G	S	Q	Y	L	L	N	W	C	V	Q	I	A	K	G	M	N	Y	L	E	D	R	R	L	V	H	R	D	L	A	A	R	N	V	L	V	K	T	P	Q	H	V	K	I	T	D	F
Template Known Secondary structure								S	S	S									T	T		B								T	S	S	S																							T	T				S				G	G	G						T	T
Template Predicted Secondary structure
Template SS confidence
		777	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.
		179	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.							.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
Predicted Secondary structure																					.	.	.	.	.	.
Query SS confidence																					.	.	.	.	.	.
Query Sequence		S	G	K	R	A	S	A	Q	R	K	A	K	D	R	I	D	L	E	R	.	.	.	.	.	.	H	Y	G	I	K	N	E	I	R	D	L	G	Y	Y	L	L	V	Y	R	K	K	M	R	N	F
Query Conservation																					.	.	.	.	.	.
Alig confidence																					.	.	.	.	.	.
Template Conservation
Template Sequence		G	L	A	K	L	L	G	A	E	E	K	V	P	I	K	W	M	A	L	E	S	I	L	H	R	I	Y	T	H	Q	S	D	V	W	S	Y	G	V	T	V	W	E	L	M	T	F	G	S	K	P
Template Known Secondary structure		S					T	T	T	T					T	T	T	S																												T	T	S			T
Template Predicted Secondary structure
Template SS confidence
		857	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions