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Job DescriptionP00634
Confidence99.14%DateWed Jan 25 15:20:09 GMT 2012
Rank28Aligned Residues268
% Identity25%Templatec2xrgA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor
Resolution3.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   65....70.........80.........90.........100.........110.........120.........130.........140....
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Query Sequence  KNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGV
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Template Sequence  PPLIIFSVDGFRAS. . . . . . . YMKKGSKVMPNIEKLRSCGTHAPYMRP. . . . . . VYPTKTFPNLYTLATGLYPESH. . . .
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T

GG.......GGGS
TTTSS
S

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   163......170...... ...180.........190.........200... ......210.........220.....
 
   145....150.........160.........170.........180.........190.........200.........210.........220....
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Query Sequence  DIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADV
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . GIVGNSMYDPVFDASFHLRGREK. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  .....................S


SSTTTT
SSSSGG....................................
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   226...230.........240........
 
   225....230.........240.........250.........260.........270.........280.........290.........300....
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Query Sequence  TLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKP
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Template Sequence  . . . . . . . . . . . . FNHRWWGGQPLWITATKQGVRAG. . . . . . . . . . . . . . . . . . . TFFWSVSIP. . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............G
TTS

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TTT

B
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   249250.........260.........270. ........280
 
   305....310.........320.........330... ......340.........350........ .360.........370.........380
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Query Sequence  AVTCTPNPQRNDSVPTLAQMTDKAIELLS. . KNEKGFFLQVEGASIDKQDHAANPC. . GQIGETVDLDEAVQRALEFAKK
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Template Sequence  . . . . . . . . . . . . . . . . HERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQ
Template Known Secondary structure  ................TTS
TTT

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   281........290.........300.........310.........320.........330.........340....
 
   381. .......390.........400
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Query Sequence  EG. . . NTLVIVTADHAHASQIVA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  LRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKYDPKTIIAALTCKKPDQHFKPYMKQHLPK
Template Known Secondary structure  TT
TTT
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SSSGGGT
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TT
BS


TTSS
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G
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   345....350.........360.........370.........380.........390.........400.........410.........420....
 
   401........410.........420.........430.........440....... ..450.........460.........470.
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Query Sequence  . . . . . PDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPH. . AANVVGLTDQTDLFYTMKAALGLK
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Template Sequence  RLHYANNRRIEDIHLLVDRRWHVARKPFQGDHGFD. NKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLK
Template Known Secondary structure  GG


SSTTS
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S
.TT
GGG
B
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GGGT

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   431........440.........450.........460..... ....470.........480.........490.........500.......
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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