Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP37621
DateThu Jan 5 11:55:56 GMT 2012
Unique Job IDfaf3552efbca5c63

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1pv7a_
Top template information
Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:LacY-like proton/sugar symporter
Confidence and coverage
Confidence:100.0% Coverage: 94%
382 residues ( 94% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MPEPVAEPALNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVMGFSAFWAGLVIS
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   .........70.........80.........90.........100.........110.........120
Sequence  LQYFATLLSRPHAGRYADSLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLG
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??
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   .........130.........140.........150.........160.........170.........180
Sequence  RVILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQ
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   .........190.........200.........210.........220.........230.........240
Sequence  ALALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLGRVWLYGMALALASAGFGVIATF
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   .........250.........260.........270.........280.........290.........300
Sequence  ITLFYDAKGWDGAAFALTLFSCAFVGTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGV
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   .........310.........320.........330.........340.........350.........360
Sequence  ATMPWMAKIGVLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLA
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   .........370.........380.........390.........400.....
Sequence  GLVMSWAGVPVIYLAAAGLVAIALLLTWRLKKRPPEHVPEAASSS
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??????????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1pv7 chain A

3D model

Region: 15 - 396
Aligned: 382
Modelled: 382
Confidence: 100.0%
Identity: 14%
Fold: MFS general substrate transporter
Superfamily: MFS general substrate transporter
Family: LacY-like proton/sugar symporter

Phyre2

PDB 1pw4 chain A

3D model

Region: 2 - 404
Aligned: 398
Modelled: 403
Confidence: 100.0%
Identity: 16%
Fold: MFS general substrate transporter
Superfamily: MFS general substrate transporter
Family: Glycerol-3-phosphate transporter

Phyre2

PDB 2gfp chain A

3D model

Region: 19 - 384
Aligned: 356
Modelled: 366
Confidence: 100.0%
Identity: 13%
PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein d;
PDBTitle: structure of the multidrug transporter emrd from2 escherichia coli

Phyre2

PDB 3o7p chain A

3D model

Region: 20 - 394
Aligned: 367
Modelled: 375
Confidence: 99.9%
Identity: 14%
PDB header:transport protein
Chain: A: PDB Molecule:l-fucose-proton symporter;
PDBTitle: crystal structure of the e.coli fucose:proton symporter, fucp (n162a)

Phyre2

PDB 2xut chain C

3D model

Region: 22 - 390
Aligned: 362
Modelled: 369
Confidence: 99.9%
Identity: 10%
PDB header:transport protein
Chain: C: PDB Molecule:proton/peptide symporter family protein;
PDBTitle: crystal structure of a proton dependent oligopeptide (pot)2 family transporter.

Phyre2

PDB 2g9p chain A

3D model

Region: 72 - 83
Aligned: 12
Modelled: 12
Confidence: 12.9%
Identity: 25%
PDB header:antimicrobial protein
Chain: A: PDB Molecule:antimicrobial peptide latarcin 2a;
PDBTitle: nmr structure of a novel antimicrobial peptide, latarcin 2a,2 from spider (lachesana tarabaevi) venom

Phyre2

PDB 2bbj chain B

3D model

Region: 373 - 394
Aligned: 22
Modelled: 22
Confidence: 9.1%
Identity: 23%
PDB header:metal transport/membrane protein
Chain: B: PDB Molecule:divalent cation transport-related protein;
PDBTitle: crystal structure of the cora mg2+ transporter

Phyre2

PDB 2jp3 chain A

3D model

Region: 364 - 404
Aligned: 41
Modelled: 41
Confidence: 5.9%
Identity: 27%
PDB header:transcription
Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4;
PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles

Phyre2
1

d1pv7a_
2

d1pw4a_
3

c2gfpA_
4

c3o7pA_
5

c2xutC_
6

c2g9pA_
7

c2bbjB_
8

c2jp3A_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1pv7a_



100.0 14 Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:LacY-like proton/sugar symporter
2d1pw4a_



100.0 16 Fold:MFS general substrate transporter
Superfamily:MFS general substrate transporter
Family:Glycerol-3-phosphate transporter
3c2gfpA_



100.0 13 PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein d;
PDBTitle: structure of the multidrug transporter emrd from2 escherichia coli
4c3o7pA_



99.9 14 PDB header:transport protein
Chain: A: PDB Molecule:l-fucose-proton symporter;
PDBTitle: crystal structure of the e.coli fucose:proton symporter, fucp (n162a)
5c2xutC_



99.9 10 PDB header:transport protein
Chain: C: PDB Molecule:proton/peptide symporter family protein;
PDBTitle: crystal structure of a proton dependent oligopeptide (pot)2 family transporter.
6c2g9pA_



12.9 25 PDB header:antimicrobial protein
Chain: A: PDB Molecule:antimicrobial peptide latarcin 2a;
PDBTitle: nmr structure of a novel antimicrobial peptide, latarcin 2a,2 from spider (lachesana tarabaevi) venom
7c2bbjB_



9.1 23 PDB header:metal transport/membrane protein
Chain: B: PDB Molecule:divalent cation transport-related protein;
PDBTitle: crystal structure of the cora mg2+ transporter
8c2jp3A_



5.9 27 PDB header:transcription
Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4;
PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0