Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0AB93
DateThu Jan 5 11:14:57 GMT 2012
Unique Job IDfa828542a561b8a5

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2w8aC_
Top template information
PDB header:membrane protein
Chain: C: PDB Molecule:glycine betaine transporter betp;
PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate
Confidence and coverage
Confidence: 43.5% Coverage: 28%
119 residues ( 28% of your sequence) have been modelled with 43.5% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Please note: You must be registered and logged in to use Phyrealarm.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAF
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   .........70.........80.........90.........100.........110.........120
Sequence  IAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTP
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   .........130.........140.........150.........160.........170.........180
Sequence  IVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLVNIVSADFFGLGFREYASVMV
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??????



















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   .........190.........200.........210.........220.........230.........240
Sequence  PVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFV
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   .........250.........260.........270.........280.........290.........300
Sequence  LEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAG
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   .........310.........320.........330.........340.........350.........360
Sequence  LTEYLSGVLNVLADNGLWAATLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEA
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????????

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   .........370.........380.........390.........400.........410.........420
Sequence  MVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGYYFRTGIIMTLPVLFVTLAA
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   .........
Sequence  LALRLSFTL
Secondary structure 

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Disorder 





???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2w8a chain C

3D model

Region: 92 - 221
Aligned: 119
Modelled: 130
Confidence: 43.5%
Identity: 10%
PDB header:membrane protein
Chain: C: PDB Molecule:glycine betaine transporter betp;
PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate

Phyre2

PDB 3qnq chain D

3D model

Region: 180 - 216
Aligned: 37
Modelled: 37
Confidence: 39.8%
Identity: 14%
PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system

Phyre2

PDB 2bbj chain B

3D model

Region: 160 - 202
Aligned: 40
Modelled: 43
Confidence: 25.8%
Identity: 25%
PDB header:metal transport/membrane protein
Chain: B: PDB Molecule:divalent cation transport-related protein;
PDBTitle: crystal structure of the cora mg2+ transporter

Phyre2

PDB 3mk7 chain F

3D model

Region: 175 - 247
Aligned: 73
Modelled: 73
Confidence: 9.4%
Identity: 12%
PDB header:oxidoreductase
Chain: F: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit p;
PDBTitle: the structure of cbb3 cytochrome oxidase

Phyre2

PDB 3rfr chain I

3D model

Region: 151 - 241
Aligned: 90
Modelled: 91
Confidence: 8.5%
Identity: 18%
PDB header:oxidoreductase
Chain: I: PDB Molecule:pmob;
PDBTitle: crystal structure of particulate methane monooxygenase (pmmo) from2 methylocystis sp. strain m

Phyre2

PDB 1vry chain A

3D model

Region: 19 - 79
Aligned: 58
Modelled: 61
Confidence: 6.1%
Identity: 14%
PDB header:membrane protein
Chain: A: PDB Molecule:glycine receptor alpha-1 chain;
PDBTitle: second and third transmembrane domains of the alpha-12 subunit of human glycine receptor

Phyre2
1

c2w8aC_
2

c3qnqD_
3

c2bbjB_
4

c3mk7F_
5

c3rfrI_
6

c1vryA_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2w8aC_



43.5 10 PDB header:membrane protein
Chain: C: PDB Molecule:glycine betaine transporter betp;
PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate
2c3qnqD_



39.8 14 PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system
3c2bbjB_



25.8 25 PDB header:metal transport/membrane protein
Chain: B: PDB Molecule:divalent cation transport-related protein;
PDBTitle: crystal structure of the cora mg2+ transporter
4c3mk7F_



9.4 12 PDB header:oxidoreductase
Chain: F: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit p;
PDBTitle: the structure of cbb3 cytochrome oxidase
5c3rfrI_



8.5 18 PDB header:oxidoreductase
Chain: I: PDB Molecule:pmob;
PDBTitle: crystal structure of particulate methane monooxygenase (pmmo) from2 methylocystis sp. strain m
6c1vryA_



6.1 14 PDB header:membrane protein
Chain: A: PDB Molecule:glycine receptor alpha-1 chain;
PDBTitle: second and third transmembrane domains of the alpha-12 subunit of human glycine receptor

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0