|   |
1 | . | |
|
. | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | |
50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
| . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  | . |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | D | . |
. |
L | S | L | L | K | A | L | S | E | A | D | A | I | A | S | S | E | Q | E | V | R | Q | I | L | L | E | E | A | D | R | L | Q | K | E | V | R | F | D | G | L | G | S | V | L | I | R | L | . |
N | E | S | T | G | P | K | V | M | I | C | A | H | M | D | E | V | G | F | M | V | R | S | I | S | R | E | G |
Query Conservation |   |
|   | . | . |
|   |   |
|   |   |
|
|   |
|
|
|   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |
|
|
|
|
|   |   | . |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|   |   |
|   |   |
|
|   |
|
|
|   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |
|
|
|   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | D | E | T | L | T | X | L | K | D | L | T | D | A | K | G | I | P | G | N | E | R | E | V | R | Q | V | X | K | S | Y | I | E | P | F | A | D | E | V | T | T | D | R | L | G | S | L | I | A | K | K | T | G | A | E | N | G | P | K | I | X | I | A | G | H | L | D | E | V | G | F | X | V | T | Q | I | T | D | K | G |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  | S |
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  | G | G | G |
| S |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  | S | S | T | T | S |
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
| T | T | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | I | D | V | L | P | V | G | N | V | R | M | A | A | R | Q | L | Q | P | V | R | I | T | T | R | E | E | C | K | I | P | G | L | L | D | G | D | R | Q | G | N | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
V | S | A | M | R | V | D | I | G | A | R | S | Y | D | E | V | M | Q | A | G | I | R | P | G | D | R | V | T | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |
Template Sequence |   |
F | I | R | F | Q | T | V | G | G | W | W | A | Q | V | X | L | A | Q | R | V | T | I | V | T | K | K | G | E | I | T | G | V | I | G | S | K | P | P | H | I | L | S | P | E | A | R | K | K | S | V | E | I | K | D | X | F | I | D | I | G | A | S | S | R | E | E | A | L | E | W | G | V | L | P | G | D | X | I | V | P |
Template Known Secondary structure |   |
|  |  |  |  |  |  | S |
|
|
| G | G | G | T | T | T |
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
|
|
| G | G | G | S |
| T | T | T | T | T | S |
|
|
| G | G | G |
|  |  |  |
| S |
| S | S |  |  |  |  |  |  | T | T |
|
| T | T |
|  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
  |
  |   |
149 | 150 | . | . | . | . | . | . | . | . | . | 160 | |
. | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|  |  | . |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | T | T | F | Q | V | L | P | H | Q | R | V | . |
M | G | K | A | F | D | D | R | L | G | C | Y | L | L | V | T | L | L | R | E | L | H | D | A | E | L | P | A | E | V | W | L | V | A | S | S | S | E | E | V | G | L | R | G | G | Q | T | A | T | R | A | V | S | P | D | V | A | I | V | L | D | T | A | C | W | A | K |
Query Conservation |   |
  |   |   |   |   |
|   |
|   |   |   |
| . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
H | F | E | F | T | V | X | N | N | E | K | F | L | L | A | K | A | W | D | N | R | I | G | C | A | I | A | I | D | V | L | R | N | L | Q | N | T | D | H | P | N | I | V | Y | G | V | G | T | V | Q | E | E | V | G | L | R | G | A | K | T | A | A | H | T | I | Q | P | D | I | A | F | G | V | D | V | G | I | A | G | D |
Template Known Secondary structure |   |
|
|
|
|  |  |
| S | S | T | T |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
| S | S |  |  |  |  |  |  |  | S |
|
| T | T | T | S |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
  |
  |   |
228 | . | 230 | . | . | . | . | . | . | |
. | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  | . |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | F | D | Y | G | A | A | N | H | . |
R | Q | I | G | N | G | P | M | L | V | L | S | D | K | S | L | I | A | P | P | K | L | T | A | W | V | E | T | V | A | A | E | I | G | V | P | L | Q | A | D | M | F | S | N | G | G | T | D | G | G | A | V | H | L | T | G | T | G | V | P | T | V | V | M | G | P | A | T | R | H |
Query Conservation |   |
  |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
T | P | G | I | S | E | K | E | A | Q | S | K | X | G | K | G | P | Q | I | I | V | Y | D | A | S | X | V | S | H | K | G | L | R | D | A | V | V | A | T | A | E | E | A | G | I | P | Y | Q | F | D | A | I | A | G | G | G | T | D | S | G | A | I | H | L | T | A | N | G | V | P | A | L | S | I | T | I | A | T | R | Y |
Template Known Secondary structure |   |
S | T | T |
|
| T | T | T |
|
|
|
| T | T | S |
|
|  |  |  |  |  |  | T | T |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |  | T | T |
|
|
| T |  |  |  |  | T | T | S | T | T |
|
|
|  |  |  |  |  |  |  |  | B | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . |
  |
  |   |
307 | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | H | C | A | A | S | I | A | D | C | R | D | I | L | Q | M | Q | Q | L | L | S | A | L | I | Q | R | L | T | R | E | T | V | V | Q | L | T |
Query Conservation |   |
  |
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | H | T | H | A | A | X | L | H | R | D | D | Y | E | N | A | V | K | L | I | T | E | V | I | K | K | L | D | R | K | T | V | D | E | I | T |
Template Known Secondary structure |   |
T | T | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
324 | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . |
  |