|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | |
. | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | T | Q | W | P | S | P | A | K | L | N | L | F | L | Y | I | T | G | Q | R | A | D | G | Y | H | T | L | Q | T | L | F | Q | F | L | D | . |
Y | G | D | T | I | S | I | E | L | R | D | D | G | D | I | R | L | L | T | P | V | E | G | V | E | H | E | D | N | L | I | V | R | A | A | R | L | L | M | K | T | A | A | D |
Query Conservation |   |
  |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |
|
|
|
|   |   |   |
|
|   |   |
|
|
| . |
|   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |   |
|
|
|
|
|   |
|   | . | . | . | . |
|
|
|   |
| . |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . |
Template Sequence |   |
V | G | V | G | Q | A | H | S | K | I | I | L | I | . |
. |
. |
. |
G | E | H | A | V | . |
V | Y | G | Y | P | A | I | S | L | P | L | L | E | V | E | V | T | C | K | V | V | P | A | E | S | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
W | R | L | Y | E | E | D | T | L | S | M | A | V | Y | A | S | L | E | Y | L | N | . |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
| T | T | G | G | . | G | G | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|  |  |  |  |  |  | . | . | . | . |
|
|
|  |  | . |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | |
|
|
|
. | . | 20 | . | . | |
. | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | |
  |
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | 140 | . | . | . | . | . | . | . | . | . | 150 | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | G | R | L | P | T | G | S | G | A | N | I | S | I | D | K | R | L | P | M | G | G | G | L | G | G | G | S | S | N | A | A | T | V | L | V | A | L | N | H | L | W | Q | C | G | L | S | M | D | E | L | A | E | M | G | L | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | A | D | V | P | V | F | V | R | G | H | A | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |
|
|
|
|
|
|
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . |
|   |
|
|   |   |   |   |   |
|
|   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . |
|   |   |
|   |
|   |
|   |
|
|   |
|   |
|
|
|
|
|
|
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |
|
|   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
I | T | E | A | C | I | R | C | E | I | D | E | K | R | G | M | G | S | S | A | A | I | S | I | A | A | I | R | A | V | F | D | Y | Y | Q | A | D | L | P | H | D | V | L | E | I | L | V | N | R | A | E | M | I | A | H | M | N | P | S | G | L | D | A | K | T | C | L | S | D | Q | P | I |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . |
| S |
|
|
|  |  |  |  |  |
|
|
| G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| S |  |  |  |  |  |  | T |
| S | S |
|  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . |
  |
  |   |
152 | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
| . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
F | A | E | G | V | G | E | I | L | T | P | V | D | P | P | . |
E | K | W | Y | L | V | A | H | P | G | V | S | I | P | T | P | V | I | F | K | D | P | E | L | P | R | N | T | P | K | R | S | I | . |
. |
. |
. |
. |
. |
. |
E | T | L | L | K | C | E | F | S | N | D | C | E | V | I | A | R | K | R | F | . |
. |
. |
. |
Query Conservation |   |
  |   |   |
|   |
|   |   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |
|   | . | . | . | . |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | F | I | . |
K | N | V | G | F | T | E | L | E | M | D | L | S | A | Y | L | V | I | A | D | T | G | V | Y | G | H | T | R | E | A | I | Q | V | V | Q | N | K | G | K | D | A | L | P | F | L | H | A | L | G | E | L | T | Q | Q | A | E | I | A | I | S | Q | K | D | A | E | G | L | G | Q | I | L | S | Q | A | H | L |
Template Known Secondary structure |   |
 |  |  | . | T | T | T |  |  |  |  |
|
|
|
|
| S |
|  |  |  |  |  |  |
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  | T | G | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
146 | . | . | |
. | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | |
|
. | . | . | . | . | 240 | . | . | |
|
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | |
. | . | . | . | . | . | 270 | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | E | V | D | A | V | L | S | W | L | L | E | Y | A | P | . |
. |
S | R | L | T | G | T | G | A | . |
. |
C | V | F | A | E | F | D | T | E | S | E | A | R | Q | V | L | E | Q | A | P | E | . |
W | L | N | G | F | V | A | K | G | A |
Query Conservation |   |
. | . | . | . | . | . | . | . | . |
|   |
|   |   |
|   |   |   |
|   |   |   |
|
| . | . |
|   |
|
|
|
|
|   | . | . |
|
|   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   | . |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|
|
|
|   |
|
|   |
|   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |
Template Sequence |   |
H | L | K | E | I | G | V | S | S | L | E | A | D | S | L | V | E | T | A | L | S | H | G | A | L | G | A | K | M | S | G | G | G | L | G | G | C | I | I | A | L | V | T | N | L | T | H | A | Q | E | L | A | E | R | L | E | E | K | G | A | V | Q | T | W | I | E | S | L |
Template Known Secondary structure |   |
 |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| S |  |  |  |  |  | S | S | S | S | S | S |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
225 | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . |
  |