Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	P	Y	Q	R	Q	F	I	E	F	A	L	S	K	Q	V	L	K	F	G	E	F	T	L	K	S	G	R	K	S	P	Y	F	F	N	A	G	L	F	N	T	G	R	D	L	A	L	L	G	R	F	Y	A	E	A	L	V	D	S
Secondary structure
SS confidence
Disorder		?	?																																						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	I	E	F	D	L	L	F	G	P	A	Y	K	G	I	P	I	A	T	T	T	A	V	A	L	A	E	H	H	D	L	D	L	P	Y	C	F	N	R	K	E	A	K	D	H	G	E	G	G	N	L	V	G	S	A	L	Q	G	R	V
Secondary structure
SS confidence
Disorder																													?	?															?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		M	L	V	D	D	V	I	T	A	G	T	A	I	R	E	S	M	E	I	I	Q	A	N	G	A	T	L	A	G	V	L	I	S	L	D	R	Q	E	R	G	R	G	E	I	S	A	I	Q	E	V	E	R	D	Y	N	C	K	V	I	S
Secondary structure
SS confidence
Disorder																																								?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.
Sequence		I	I	T	L	K	D	L	I	A	Y	L	E	E	K	P	E	M	A	E	H	L	A	A	V	K	A	Y	R	E	E	F	G	V
Secondary structure
SS confidence
Disorder																		?														?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1lh0 chain A Region: 1 - 213 Aligned: 213 Modelled: 213 Confidence: 100.0% Identity: 97% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 3n2l chain A Region: 1 - 213 Aligned: 205 Modelled: 213 Confidence: 100.0% Identity: 80% PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 2.1 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase (pyre) from vibrio cholerae o1 biovar eltor3 str. n16961 Phyre2 PDB 2prz chain B Region: 1 - 213 Aligned: 206 Modelled: 213 Confidence: 100.0% Identity: 47% PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase 1; PDBTitle: s. cerevisiae orotate phosphoribosyltransferase complexed2 with omp Phyre2 PDB 3mjd chain A Region: 3 - 212 Aligned: 203 Modelled: 210 Confidence: 100.0% Identity: 45% PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.9 angstrom crystal structure of orotate2 phosphoribosyltransferase (pyre) francisella tularensis. Phyre2 PDB 2wns chain B Region: 7 - 210 Aligned: 191 Modelled: 204 Confidence: 100.0% Identity: 28% PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: human orotate phosphoribosyltransferase (oprtase) domain of2 uridine 5'-monophosphate synthase (umps) in complex with3 its substrate orotidine 5'-monophosphate (omp) Phyre2 PDB 3qw4 chain B Region: 2 - 211 Aligned: 188 Modelled: 210 Confidence: 100.0% Identity: 24% PDB header:transferase, lyase Chain: B: PDB Molecule:ump synthase; PDBTitle: structure of leishmania donovani ump synthase Phyre2 PDB 3dez chain A Region: 3 - 209 Aligned: 190 Modelled: 200 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 streptococcus mutans Phyre2 PDB 2aee chain A domain 1 Region: 1 - 209 Aligned: 192 Modelled: 202 Confidence: 100.0% Identity: 22% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 3m3h chain A Region: 2 - 209 Aligned: 184 Modelled: 200 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.75 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase from bacillus anthracis str. 'ames3 ancestor' Phyre2 PDB 2yzk chain C Region: 8 - 191 Aligned: 162 Modelled: 169 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: C: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 aeropyrum pernix Phyre2 PDB 1mzv chain A Region: 6 - 187 Aligned: 172 Modelled: 180 Confidence: 100.0% Identity: 20% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 2p1z chain A Region: 29 - 187 Aligned: 144 Modelled: 159 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase; PDBTitle: crystal structure of phosphoribosyltransferase from corynebacterium2 diphtheriae Phyre2 PDB 1qb7 chain A Region: 10 - 183 Aligned: 167 Modelled: 174 Confidence: 100.0% Identity: 19% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1y0b chain A domain 1 Region: 6 - 187 Aligned: 160 Modelled: 175 Confidence: 100.0% Identity: 20% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1o57 chain A domain 2 Region: 2 - 184 Aligned: 160 Modelled: 175 Confidence: 99.9% Identity: 21% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 2dy0 chain A Region: 6 - 184 Aligned: 158 Modelled: 171 Confidence: 99.9% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli Phyre2 PDB 1o57 chain A Region: 6 - 184 Aligned: 150 Modelled: 177 Confidence: 99.9% Identity: 19% PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis Phyre2 PDB 1zn7 chain A domain 1 Region: 11 - 184 Aligned: 155 Modelled: 174 Confidence: 99.9% Identity: 19% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1l1q chain A Region: 34 - 184 Aligned: 139 Modelled: 151 Confidence: 99.9% Identity: 18% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1g2q chain A Region: 34 - 182 Aligned: 133 Modelled: 149 Confidence: 99.9% Identity: 23% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 1 d1lh0a_ 2 c3n2lA_ 3 c2przB_ 4 c3mjdA_ 5 c2wnsB_ 6 c3qw4B_ 7 c3dezA_ 8 d2aeea1 9 c3m3hA_ 10 c2yzkC_ 11 d1mzva_ 12 c2p1zA_ 13 d1qb7a_ 14 d1y0ba1 15 d1o57a2 16 c2dy0A_ 17 c1o57A_ 18 d1zn7a1 19 d1l1qa_ 20 d1g2qa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1lh0a_ 100.0 97 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 2 c3n2lA_ 100.0 80 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 2.1 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase (pyre) from vibrio cholerae o1 biovar eltor3 str. n16961 3 c2przB_ 100.0 47 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase 1; PDBTitle: s. cerevisiae orotate phosphoribosyltransferase complexed2 with omp 4 c3mjdA_ 100.0 45 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.9 angstrom crystal structure of orotate2 phosphoribosyltransferase (pyre) francisella tularensis. 5 c2wnsB_ 100.0 28 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: human orotate phosphoribosyltransferase (oprtase) domain of2 uridine 5'-monophosphate synthase (umps) in complex with3 its substrate orotidine 5'-monophosphate (omp) 6 c3qw4B_ 100.0 24 PDB header:transferase, lyase Chain: B: PDB Molecule:ump synthase; PDBTitle: structure of leishmania donovani ump synthase 7 c3dezA_ 100.0 18 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 streptococcus mutans 8 d2aeea1 100.0 22 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 9 c3m3hA_ 100.0 21 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.75 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase from bacillus anthracis str. 'ames3 ancestor' 10 c2yzkC_ 100.0 27 PDB header:transferase Chain: C: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 aeropyrum pernix 11 d1mzva_ 100.0 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 12 c2p1zA_ 100.0 20 PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase; PDBTitle: crystal structure of phosphoribosyltransferase from corynebacterium2 diphtheriae 13 d1qb7a_ 100.0 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 14 d1y0ba1 100.0 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 15 d1o57a2 99.9 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 16 c2dy0A_ 99.9 19 PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli 17 c1o57A_ 99.9 19 PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis 18 d1zn7a1 99.9 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 19 d1l1qa_ 99.9 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 20 d1g2qa_ 99.9 23 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 21 d1vcha1 not modelled 99.8 23 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 22 d1vdma1 not modelled 99.8 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 23 d2igba1 not modelled 99.8 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 24 d1ufra_ not modelled 99.7 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 25 d1hgxa_ not modelled 99.7 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 26 d1w30a_ not modelled 99.7 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 27 c3o7mD_ not modelled 99.7 11 PDB header:transferase Chain: D: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 1.98 angstrom resolution crystal structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-2) from bacillus anthracis str. 'ames3 ancestor' 28 d1a3ca_ not modelled 99.7 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 29 d1g9sa_ not modelled 99.7 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 30 c2ywtA_ not modelled 99.7 12 PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hypoxanthine-guanine2 phosphoribosyltransferase with gmp from thermus3 thermophilus hb8 31 d1j7ja_ not modelled 99.7 12 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 32 d1z7ga1 not modelled 99.7 12 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 33 d1pzma_ not modelled 99.7 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 34 d1tc1a_ not modelled 99.7 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 35 c3kb8A_ not modelled 99.7 14 PDB header:transferase Chain: A: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 2.09 angstrom resolution structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-1) from bacillus anthracis str. 'ames3 ancestor' in complex with gmp 36 c1pzmB_ not modelled 99.6 13 PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hgprt-ase from leishmania tarentolae in complex2 with gmp 37 d1yfza1 not modelled 99.6 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 38 c1yfzA_ not modelled 99.6 18 PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: novel imp binding in feedback inhibition of hypoxanthine-guanine2 phosphoribosyltransferase from thermoanaerobacter tengcongensis 39 d1p17b_ not modelled 99.6 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 40 c2jkzB_ not modelled 99.6 16 PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: saccharomyces cerevisiae hypoxanthine-guanine2 phosphoribosyltransferase in complex with gmp (guanosine 5'3 -monophosphate) (orthorhombic crystal form) 41 d1ecfa1 not modelled 99.5 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 42 d1nula_ not modelled 99.5 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 43 d1gph11 not modelled 99.5 25 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 44 c2jbhA_ not modelled 99.5 12 PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase domain-containing protein 1; PDBTitle: human phosphoribosyl transferase domain containing 1 45 c3lpnB_ not modelled 99.5 18 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of the phosphoribosylpyrophosphate (prpp) synthetase2 from thermoplasma volcanium in complex with an atp analog (ampcpp). 46 c1ecjB_ not modelled 99.4 17 PDB header:transferase Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer 47 d1wd5a_ not modelled 99.4 24 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 48 c3efhB_ not modelled 99.4 17 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1; PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1 49 d1fsga_ not modelled 99.4 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 50 d1cjba_ not modelled 99.4 11 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 51 c1gph1_ not modelled 99.4 26 PDB header:transferase(glutamine amidotransferase) Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase; PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis 52 c1dkrB_ not modelled 99.3 22 PDB header:transferase Chain: B: PDB Molecule:phosphoribosyl pyrophosphate synthetase; PDBTitle: crystal structures of bacillus subtilis phosphoribosylpyrophosphate2 synthetase: molecular basis of allosteric inhibition and activation. 53 c2c4kD_ not modelled 99.2 17 PDB header:regulatory protein Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase- PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39) 54 d1dkua2 not modelled 99.2 24 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 55 d1u9ya2 not modelled 99.2 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 56 d2c4ka2 not modelled 99.2 22 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 57 c1u9yD_ not modelled 99.1 21 PDB header:transferase Chain: D: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of phosphoribosyl diphosphate synthase2 from methanocaldococcus jannaschii 58 c3dahB_ not modelled 98.9 16 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: 2.3 a crystal structure of ribose-phosphate pyrophosphokinase from2 burkholderia pseudomallei 59 d1dqna_ not modelled 98.3 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 60 c2ehjA_ not modelled 98.3 12 PDB header:transferase Chain: A: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of uracil phosphoribosyl transferase 61 d1o5oa_ not modelled 98.2 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 62 c2e55D_ not modelled 98.2 9 PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of aq2163 protein from aquifex aeolicus 63 d1i5ea_ not modelled 98.1 11 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 64 d1xtta1 not modelled 97.7 9 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 65 d1bd3a_ not modelled 97.7 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 66 c3dmpD_ not modelled 97.6 10 PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: 2.6 a crystal structure of uracil phosphoribosyltransferase2 from burkholderia pseudomallei 67 d1v9sa1 not modelled 97.4 14 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 68 d1g57a_ not modelled 91.5 25 Fold:YrdC/RibB Superfamily:YrdC/RibB Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB 69 d1tksa_ not modelled 90.8 14 Fold:YrdC/RibB Superfamily:YrdC/RibB Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB 70 d1snna_ not modelled 89.5 8 Fold:YrdC/RibB Superfamily:YrdC/RibB Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB 71 c3mioA_ not modelled 89.3 15 PDB header:lyase Chain: A: PDB Molecule:3,4-dihydroxy-2-butanone 4-phosphate synthase; PDBTitle: crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase2 domain from mycobacterium tuberculosis at ph 6.00 72 d1k4ia_ not modelled 83.5 20 Fold:YrdC/RibB Superfamily:YrdC/RibB Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB 73 d1s8na_ not modelled 79.4 18 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 74 d1u9ya1 not modelled 69.7 11 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 75 c2vspA_ not modelled 62.3 15 PDB header:transport protein Chain: A: PDB Molecule:pdz domain-containing protein 1; PDBTitle: crystal structure of the fourth pdz domain of pdz domain-2 containing protein 1 76 d1vaea_ not modelled 60.4 12 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 77 c3l4fD_ not modelled 59.9 18 PDB header:signaling protein/protein binding Chain: D: PDB Molecule:sh3 and multiple ankyrin repeat domains protein PDBTitle: crystal structure of betapix coiled-coil domain and shank2 pdz complex 78 c2vsvB_ not modelled 57.2 12 PDB header:protein-binding Chain: B: PDB Molecule:rhophilin-2; PDBTitle: crystal structure of the pdz domain of human rhophilin-2 79 d2c4ka1 not modelled 57.1 11 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 80 d1m5za_ not modelled 54.8 23 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 81 c3eggC_ not modelled 54.4 10 PDB header:hydrolase Chain: C: PDB Molecule:spinophilin; PDBTitle: crystal structure of a complex between protein phosphatase 1 alpha2 (pp1) and the pp1 binding and pdz domains of spinophilin 82 c2d90A_ not modelled 54.1 15 PDB header:protein binding Chain: A: PDB Molecule:pdz domain containing protein 1; PDBTitle: solution structure of the third pdz domain of pdz domain2 containing protein 1 83 c3r2uC_ not modelled 52.6 18 PDB header:hydrolase Chain: C: PDB Molecule:metallo-beta-lactamase family protein; PDBTitle: 2.1 angstrom resolution crystal structure of metallo-beta-lactamase2 from staphylococcus aureus subsp. aureus col 84 c2jxoA_ not modelled 52.6 23 PDB header:protein binding Chain: A: PDB Molecule:ezrin-radixin-moesin-binding phosphoprotein 50; PDBTitle: structure of the second pdz domain of nherf-1 85 c3mmnA_ not modelled 51.8 23 PDB header:transferase Chain: A: PDB Molecule:histidine kinase homolog; PDBTitle: crystal structure of the receiver domain of the histidine kinase cki12 from arabidopsis thaliana complexed with mg2+ 86 c1a2oB_ not modelled 51.5 20 PDB header:bacterial chemotaxis Chain: B: PDB Molecule:cheb methylesterase; PDBTitle: structural basis for methylesterase cheb regulation by a2 phosphorylation-activated domain 87 d1q3oa_ not modelled 51.3 18 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 88 c2o2tB_ not modelled 50.8 10 PDB header:structural protein Chain: B: PDB Molecule:multiple pdz domain protein; PDBTitle: the crystal structure of the 1st pdz domain of mpdz 89 c3diwB_ not modelled 48.2 10 PDB header:signaling protein/cell adhesion Chain: B: PDB Molecule:tax1-binding protein 3; PDBTitle: c-terminal beta-catenin bound tip-1 structure 90 c2kjdA_ not modelled 47.5 23 PDB header:signaling protein Chain: A: PDB Molecule:sodium/hydrogen exchange regulatory cofactor nhe- PDBTitle: solution structure of extended pdz2 domain from nherf1 (150-2 270) 91 d1ihja_ not modelled 47.5 6 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 92 c3qglD_ not modelled 47.2 20 PDB header:protein binding Chain: D: PDB Molecule:sorting nexin-27; PDBTitle: crystal structure of pdz domain of sorting nexin 27 (snx27) in complex2 with the eseskv peptide corresponding to the c-terminal tail of girk3 93 c1r6jA_ not modelled 47.1 10 PDB header:membrane protein Chain: A: PDB Molecule:syntenin 1; PDBTitle: ultrahigh resolution crystal structure of syntenin pdz2 94 d1r6ja_ not modelled 47.1 10 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 95 c1nteA_ not modelled 47.1 10 PDB header:signaling protein Chain: A: PDB Molecule:syntenin 1; PDBTitle: crystal structure analysis of the second pdz domain of2 syntenin 96 c1j6uA_ not modelled 46.6 11 PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramate-alanine ligase murc; PDBTitle: crystal structure of udp-n-acetylmuramate-alanine ligase2 murc (tm0231) from thermotoga maritima at 2.3 a resolution 97 c2eeiA_ not modelled 46.2 15 PDB header:metal binding protein Chain: A: PDB Molecule:pdz domain-containing protein 1; PDBTitle: solution structure of second pdz domain of pdz domain2 containing protein 1 98 c1obyA_ not modelled 46.0 10 PDB header:cell adhesion Chain: A: PDB Molecule:syntenin 1; PDBTitle: crystal structure of the complex of pdz2 of syntenin with2 a syndecan-4 peptide. 99 d1dcfa_ not modelled 44.9 15 Fold:Flavodoxin-like Superfamily:CheY-like Family:Receiver domain of the ethylene receptor 100 d1vi2a1 not modelled 44.2 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 101 d1dkua1 not modelled 44.2 11 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 102 c2kv8A_ not modelled 43.8 13 PDB header:signaling protein Chain: A: PDB Molecule:regulator of g-protein signaling 12; PDBTitle: solution structure ofrgs12 pdz domain 103 c2he4A_ not modelled 43.7 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:na(+)/h(+) exchange regulatory cofactor nhe-rf2; PDBTitle: the crystal structure of the second pdz domain of human2 nherf-2 (slc9a3r2) interacting with a mode 1 pdz binding3 motif 104 c2z17A_ not modelled 43.5 19 PDB header:protein binding Chain: A: PDB Molecule:pleckstrin homology sec7 and coiled-coil domains- PDBTitle: crystal sturcture of pdz domain from human pleckstrin2 homology, sec7 105 d1v6ba_ not modelled 43.0 18 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 106 d2fe5a1 not modelled 40.6 8 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 107 d1g9oa_ not modelled 40.6 13 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 108 d1y7na1 not modelled 40.2 10 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 109 c3k1rA_ not modelled 40.0 10 PDB header:structural protein Chain: A: PDB Molecule:harmonin; PDBTitle: structure of harmonin npdz1 in complex with the sam-pbm of2 sans 110 c2edzA_ not modelled 40.0 15 PDB header:signaling protein Chain: A: PDB Molecule:pdz domain-containing protein 1; PDBTitle: solution structures of the pdz domain of mus musculus pdz2 domain-containing protein 1 111 c2krgA_ not modelled 39.9 23 PDB header:signaling protein Chain: A: PDB Molecule:na(+)/h(+) exchange regulatory cofactor nhe-rf1; PDBTitle: solution structure of human sodium/ hydrogen exchange2 regulatory factor 1(150-358) 112 c2pkuA_ not modelled 39.9 15 PDB header:protein binding Chain: A: PDB Molecule:prkca-binding protein; PDBTitle: solution structure of pick1 pdz in complex with the2 carboxyl tail peptide of glur2 113 d1u3ba2 not modelled 39.8 11 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 114 c2dmzA_ not modelled 39.7 20 PDB header:protein binding Chain: A: PDB Molecule:inad-like protein; PDBTitle: solution structure of the third pdz domain of human inad-2 like protein 115 c1obyB_ not modelled 39.3 10 PDB header:cell adhesion Chain: B: PDB Molecule:syntenin 1; PDBTitle: crystal structure of the complex of pdz2 of syntenin with2 a syndecan-4 peptide. 116 d1obxa_ not modelled 39.3 10 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 117 c1obxA_ not modelled 39.3 10 PDB header:cell adhesion Chain: A: PDB Molecule:syntenin 1; PDBTitle: crystal structure of the complex of pdz2 of syntenin with2 an interleukin 5 receptor alpha peptide. 118 d2j01f1 not modelled 38.9 13 Fold:Ribosomal protein L4 Superfamily:Ribosomal protein L4 Family:Ribosomal protein L4 119 d1uita_ not modelled 38.1 10 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 120 d1wjla_ not modelled 38.1 21 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0