|   |
1 | . | . | . | . | . | . | . | . | |
|
|
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | R | V | L | I | V | K | T | S | . |
. |
. |
S | M | G | D | V | L | H | T | L | P | A | L | T | D | A | Q | Q | A | I | P | G | I | K | F | D | W | V | V | E | E | G | F | A | Q | I | P | S | W | H | A | A | V | E | R | V | I | P | V | A | I | R | R | W | R | K | A | W | F | S | A | P | I | K | A | E | R | K | A |
Query Conservation |   |
|
|
|
|
|
|   |   |   | . | . | . |   |
|
|
|   |
|   |   |   |
|   |
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   | . | . | . |
|
|
|
|   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
M | K | L | I | I | V | G | A | H | S | S | V | P | S | G | Y | G | R | V | M | R | A | I | V | P | R | I | S | K | . |
. |
. |
A | H | E | V | I | V | F | G | I | H | A | . |
. |
. |
. |
. |
F | G | R | S | V | H | A | N | I | E | E | F | D | A | Q | T | A | E | H | V | R | G | L | N | E | Q | G | F | Y | Y | S | G |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |
| T | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | T | S |  |  |  |  |  |  |  | S |
| . | . | . | . | . |
| S |
|
| S |
| S | S | S |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S | T | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | |
|
|
30 | . | . | . | . | . | . | . | . | . | 40 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | R | E | A | L | Q | A | E | N | Y | D | A | V | I | D | A | Q | G | L | V | K | S | A | A | L | V | T | R | L | A | H | . |
. |
. |
. |
. |
G | V | K | H | G | M | D | W | Q | T | A | R | E | P | L | A | S | L | F | Y | N | R | K | H | H | I | A | K | Q | Q | H | A | V | E | R | T | R | E | L | F | A | K | S | L |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | S | E | F | I | D | V | H | K | P | D | I | V | M | I | Y | N | D | P | I | V | I | G | N | Y | L | L | A | M | G | K | C | S | H | R | T | K | I | V | L | Y | V | D | L | V | S | K | N | I | R | E | N | L | W | W | I | F | S | H | P | K | V | V | G | V | M | A | M | S | K | C | W | I | S | D | I | C | N | Y | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | G | G | G |
|
| S |
|
|  |  |  |  |  |  |
|
|
| S | B | S |
|
| G | G | G | G | G | G | G | G |
| T | T |  |  |  |  |  |  | S | S | T |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
73 | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
  |
  |   |
153 | . | . | |
|
|
|
|
. | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
|
|
|
. | . | . | . | . | . | . | 220 | . | . | . |
Predicted Secondary structure |   |
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . |  |  |  |  |
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Y | S | . |
. |
. |
. |
. |
K | P | Q | T | Q | G | D | Y | A | I | A | Q | H | F | L | T | N | L | P | T | D | A | G | E | Y | A | V | F | L | H | A | T | T | R | D | D | K | H | W | P | E | E | H | W | R | E | L | I | G | L | L | A | D | S | G | I | R | . |
. |
. |
. |
I | K | L | P | W | G | A | P | H | E | E |
Query Conservation |   |
  |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   | . | . | . | . |   |
|
|   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|
| . | . |   |   |   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
C | K | V | P | I | N | I | V | S | H | F | V | D | T | K | T | I | Y | D | A | R | K | L | V | G | L | S | E | Y | N | D | D | V | L | F | L | N | M | N | R | N | T | A | R | K | R | . |
. |
L | D | I | Y | V | L | A | A | A | R | F | I | S | K | Y | P | D | A | K | V | R | F | L | C | N | S | H | H | E | S | K | F |
Template Known Secondary structure |   |
|
| S |
|  |  |  |
|
|
|
|
|
|
|
|
|
| T | T |  |  |  |  | T | T |
| G | G | G | T | T | S |  |  |  |  |
|
| S |
| S | S | G | G | G | T | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |
|
| T | T |
| S |
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | |
|
. | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 |
  |
  |   |
224 | . | . | . | . | . | 230 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | R | A | K | R | L | A | E | G | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | Y | V | E | V | L | P | K | M | S | L | E | G | V | A | R | V | L | A | G | A | K | F | V | V | S | V | D | . |
. |
. |
. |
. |
T | G | L | S | H | L | T | A | A | L | D | R | P | N | I | T | V | Y | G | P | T | D | P | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|   |   |
|   |
|   |
|   |   |
| . | . | . | . | . |
|
|   |   |
|
|
|   |
|
|
|   |
|   |
|   |
|
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
|   |
|
|
|   |
| . |   |   |   |
|   |   |
Template Sequence |   |
D | L | H | S | I | A | L | R | E | L | V | A | S | G | V | D | N | V | F | T | H | L | N | K | I | M | I | N | R | T | V | L | T | D | E | R | V | D | M | M | Y | N | A | C | D | V | I | V | N | C | S | S | G | E | G | F | G | L | C | S | A | E | G | A | V | L | G | K | P | L | I | I | S | . |
A | V | G | G | A | D |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
|  |  |  |  |  | T | T |  |  |  |  |
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |
|
| S |
|
| S | S |
|  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  | . |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  | . |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
231 | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | |
. | . | . | . | . | . |
  |
  |   |
286 | . | . | . | 290 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | I | G | G | Y | G | K | N | Q | M | V | C | R | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | R | E | N | L | I | N | L | N | S | Q | A | V | L | E | K | L | S | S | L |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
Template Sequence |   |
D | Y | F | S | G | D | C | V | Y | K | I | K | P | S | A | W | I | S | V | D | D | R | D | G | I | G | G | I | E | G | I | I | D | V | D | D | L | V | E | A | F | T | F | F |
Template Known Secondary structure |   |
 |  | S |
| T | T | T | S |  |  |  |
|
|
|  |  |  |  |
| T | T | T |
| S | S |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . |
  |