|   |
54 | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | |
. | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | Y | P | E | C | Q | P | K | A | V | I | E | N | Y | A | Q | Y | A | G | V | K | P | E | Q | V | L | V | S | R | G | A | D | E | G | I | E | L | L | I | R | A | F | . |
C | E | P | G | K | D | A | I | L | Y | C | P | P | T | Y | G | M | Y | S | V | S | A | E | T | I | G | V | E | C | R | T | V | P | T | L | D | N |
Query Conservation |   |
  |
|
|   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   | . |   |   |   |
|   |
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |   |   |   |
|
|   |   |
|
|   |   |   |
|   |   | . | . |   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |
| . |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | I | L | G | D | E | D | K | K | F | E | Q | E | F | A | D | Y | C | N | V | N | . |
. |
Y | C | I | G | C | G | N | G | L | D | A | L | H | L | I | L | K | G | Y | D | I | G | F | G | . |
D | E | V | I | V | P | S | N | T | F | I | A | T | A | L | A | V | S | Y | T | G | A | K | P | I | F | V | E | P | D | I | R |
Template Known Secondary structure |   |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | . | . |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | . |
|  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|  |  | T | T |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
32 | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | |
|
. | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
. | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . |
  |
  |   |
133 | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | Q | L | D | L | Q | G | I | S | D | K | L | D | G | V | K | V | V | Y | V | C | S | P | N | N | P | T | G | Q | L | I | N | P | Q | D | F | R | T | L | L | E | L | T | R | G | K | A | I | V | V | A | D | E | A | Y | I | E | F | C | P | Q | A | S | L | A | G | W | L | A | E | Y | P | H | L | A | I | L | R | T | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |
|
|   | . | . |   |   |
|   |   |
|
|   |
|   |
|   |   |   |
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
. |
T | Y | N | I | D | P | S | L | I | E | S | A | I | T | E | K | T | K | A | I | I | A | V | H | L | Y | G | Q | P | A | D | M | D | E | I | K | R | I | A | K | . |
. |
K | Y | N | L | K | L | I | E | D | A | A | Q | A | H | G | S | L | Y | K | G | . |
M | K | V | G | S | L | G | D | A | A | G | F | S | F | Y | P |
Template Known Secondary structure |   |
. | T | T |  |  |
| G | G | G | T | G | G | G |
|
| T | T |  |  |  |  |  |  |  |
| G | G | G | S |
|
|
|  |  |  |  |  |  |  |  |  | . | . |  | T | T |
|  |  |  |  |  |
| T | T |
| T | T |
|  |  | T | T | . |  |  | T | T | S | S | S | S |  |  |  |  |  |
|
| T |
Template Predicted Secondary structure |   |
. |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
109 | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | |
|
. | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | |
. | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
  |
  |   |
213 | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | K | A | F | A | L | A | G | L | R | C | G | F | T | L | A | N | E | E | V | I | N | L | L | M | K | V | I | A | P | Y | P | L | S | T | P | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
A | D | I | A | A | Q | A | L | S | P | Q | G | I | V | A | M | R | E | R | V | A | Q | I | I | A | E | R | E | Y | L | I | A | A | L |
Query Conservation |   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
Template Sequence |   |
A | K | N | L | G | S | L | G | D | G | G | A | V | V | T | N | D | K | D | L | A | E | K | I | K | A | L | S | N | Y | G | S | E | K | K | Y | H | H | I | Y | K | G | F | N | S | R | L | D | E | L | Q | A | G | F | L | R | V | K | L | K | Y | L | D | K | W | N | E | E | R | R | K | I | A | Q | K | Y | I | A | G | I |
Template Known Secondary structure |   |
T | S | T | T |
|
| S | S |
|
|  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  | B | T | T |
| S | B | T | T | B |
|
| S |
|
|
| B |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . |
  |
  |   |
284 | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | |
|
|
|
. | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
K | E | I | P | C | V | E | Q | V | F | D | S | E | T | N | Y | I | L | A | R | F | K | . |
. |
. |
. |
A | S | S | A | V | F | K | S | L | W | D | Q | G | I | I | L | R | D | Q | N | K | Q | P | S | L | S | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
C | L | R | I | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |   |
|   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|
|
|   |
Template Sequence |   |
N | N | P | N | V | I | I | P | V | E | A | D | Y | A | K | H | V | W | Y | T | F | V | I | R | S | E | K | R | D | E | L | Q | K | Y | L | N | N | N | G | I | G | T | L | I | H | Y | P | I | P | I | H | L | Q | Q | A | Y | K | D | L | G | F | K | T | G | N | F | P | I | A | E | K | I | A | N | E | I | L | S | I | P |
Template Known Secondary structure |   |
| B | T | T | B | B |
|
|
|
|
| T | T |  |  |
|
|
| S |
|
|  |  |  |
| T | T |  |  |  |  |  |  |  |  |  |  | T | T | B |
|
| B |
| S |
| S | S |
| G | G | G | S | G | G | G | G | G | G |
|
|
| T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
265 | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . |
  |
  |   |
338 | . | |
|
|
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . |
Predicted Secondary structure |   |
 |
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | G | . |
. |
. |
T | R | E | E | S | Q | R | V | I | D | A | L | R | A | E |
Query Conservation |   |
  |   | . | . | . |
|   |
|
|   |   |   |
|   |   |
|
|
|
|
|
Alig confidence |   |
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |
|
|
|   |   |
|   |
|
|   |   |   |
Template Sequence |   |
I | W | Y | G | M | K | N | E | E | I | E | Y | V | I | D | K | I | N | A | W |
Template Known Secondary structure |   |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
345 | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . |
  |