Job Description P06986 Confidence 99.95% Date Thu Jan 5 10:59:42 GMT 2012 Rank 101 Aligned Residues 331 % Identity 15% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		12	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.			.	.	.	.	.	50	.	.	.	.	.	.															.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.
Predicted Secondary structure																																			.	.													.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																			.	.													.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		E	N	V	R	N	L	T	P	Y	Q	S	A	R	R	L	G	G	N	G	D	V	W	L	N	A	N	E	Y	P	T	A	V	E	.	.	F	Q	L	T	Q	Q	T	L	N	R	Y	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	C	Q	P	K	A	V	I	E	N	Y	A	Q	Y	A	G	V	K	P
Query Conservation																																			.	.													.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																			.	.													.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		P	K	I	Q	D	L	P	P	V	D	L	S	L	V	N	K	D	E	N	A	I	Y	F	L	G	N	S	L	G	L	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	A	N	E
Template Known Secondary structure			B	G	G	G	S	T	T			G	G	G	S		T	T		B					B	T	T	T	S			B		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T	T					G	G	G					T			G
Template Predicted Secondary structure
Template SS confidence
		49	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.
		76	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.				.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120										.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.
Predicted Secondary structure																									.	.	.																							.	.	.	.	.	.	.	.	.
Query SS confidence																									.	.	.																							.	.	.	.	.	.	.	.	.
Query Sequence		E	Q	V	L	V	S	R	G	A	D	E	G	I	E	L	L	I	R	A	F	C	E	P	.	.	.	G	K	D	A	I	L	Y	C	P	P	T	Y	G	M	Y	S	V	S	A	E	T	I	.	.	.	.	.	.	.	.	.	G	V	E	C	R	T	V	P	T	L	D	N	W	Q	L	D	L	Q	G	I	S	D	K
Query Conservation																									.	.	.																							.	.	.	.	.	.	.	.	.
Alig confidence																									.	.	.		.																					.	.	.	.	.	.	.	.	.
Template Conservation																													.
Template Sequence		K	E	I	A	L	M	N	A	L	T	V	N	L	H	L	L	M	L	S	F	F	K	P	T	P	K	R	.	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P	R	E	G	E	E	T	L	R	I	E	D	I	L	E	V
Template Known Secondary structure		G	G					S																		S	S	S	.							T	T																T	T														T	T		S	S
Template Predicted Secondary structure																													.
Template SS confidence
		129	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.		.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.
		144					.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.
Predicted Secondary structure			.	.	.	.
Query SS confidence			.	.	.	.
Query Sequence		L	.	.	.	.	D	G	V	K	V	V	Y	V	C	S	P	N	N	P	T	G	Q	L	I	N	P	Q	D	F	R	T	L	L	E	L	T	R	G	K	A	I	V	V	A	D	E	A	Y	I	E	F	C	P	Q	A	S	L	A	G	W	L	A	E	Y	P	H	L	A	I	L	R	T	L	S	K	A	F	A	L	A
Query Conservation			.	.	.	.
Alig confidence			.	.	.	.																														.	.														.	.	.	.
Template Conservation																																				.	.														.	.	.	.
Template Sequence		I	E	K	E	G	D	S	I	A	V	I	L	F	S	G	V	H	F	Y	T	G	Q	H	F	N	I	P	A	I	T	K	A	G	Q	.	.	A	K	G	C	Y	V	G	F	D	L	A	H	A	.	.	.	.	V	G	N	V	E	L	Y	L	H	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G
Template Known Secondary structure						G	G	G								S	B		T	T	T		B	B												.	.		T	T								T	T	T	.	.	.	.	T	T	T	S								T								S	S	S	T	T
Template Predicted Secondary structure																																				.	.														.	.	.	.
Template SS confidence
		208	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.			.	.	.	.	.	.	.	.	250	.	.	.	.					.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.
		220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.																												.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.
Predicted Secondary structure																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		G	L	R	C	G	F	T	L	A	N	E	E	V	I	N	L	L	M	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	K	V	I	A	P	Y	P	L	S	T	P	V	A	D	I	A	A	Q	A	L	S	P	Q	G	I	V	A	M	R	E	R	V	A	Q	I
Query Conservation																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		A	G	G	I	A	G	A	F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K	K	S
Template Known Secondary structure		T	T									G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S
Template Predicted Secondary structure
Template SS confidence
		282	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.
		273	.	.	.	.	.	.	280	.	.	.	.	.		.	.	.	.	290	.	.	.	.	.	.					.	.	.	300	.	.	.	.	.		.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.					340	.	.
Predicted Secondary structure															.												.	.	.	.										.																																			.	.	.	.
Query SS confidence															.												.	.	.	.										.																																			.	.	.	.
Query Sequence		I	A	E	R	E	Y	L	I	A	A	L	K	E	.	I	P	C	V	E	Q	V	F	D	S	E	.	.	.	.	T	N	Y	I	L	A	R	F	K	.	A	S	S	A	V	F	K	S	L	W	D	Q	G	I	I	L	R	D	Q	N	K	Q	P	S	L	S	G	C	L	R	I	T	V	G	.	.	.	.	T	R	E
Query Conservation															.												.	.	.	.										.																																			.	.	.	.
Alig confidence															.												.	.	.	.										.																			.	.	.	.	.												.	.	.	.
Template Conservation																																																											.	.	.	.	.
Template Sequence		V	L	L	T	G	Y	L	E	Y	L	I	K	H	N	Y	G	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	P	N	K	D	V	F	Q	E	L	E	K	R	G	V	V	C	D	K	.	.	.	.	.	R	N	P	N	G	I	R	V	A	P	V	P	L	Y	N	S	F	H
Template Known Secondary structure																							S		S	S	G	G	G	B		S									T	T									T	T	T						.	.	.	.	.		T	T	T					B			T	T	T
Template Predicted Secondary structure																																																											.	.	.	.	.
Template SS confidence
		362	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.						.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.
		343	.	.	.	.	.	.	350	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	S	Q	R	V	I	D	A	L	R	A	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	V	Y	K	F	T	N	L	L	T	S	I
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		446	.	.	.	450	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions