|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
. | . | . | . | 80 | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Query Sequence |   |
Y | H | R | I | P | H | S | S | L | E | V | S | T | L | G | L | G | T | M | T | F | G | E | Q | N | S | E | A | D | A | H | A | Q | L | D | Y | A | V | A | Q | G | I | N | L | I | D | V | A | E | M | Y | P | V | P | P | R | P | E | T | Q | G | L | T | E | T | Y | V | G | N | W | L | A | K | . |
H | G | S | R | E | K |
Query Conservation |   |
|
|   |
|
|   |
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |
|
|
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|   |   |
|   |   | . |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
| . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
| . |   |
|
|   |   |
|
|   |
|
|   |
|
|   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|
|   |   |
|
|
|   |   |
| . | . | . | . | . | . | . | . | . |
| . |
|
|   |   |
|
|   |
|
|   |   |   |   |   |   |
|   |   |
Template Sequence |   |
V | I | K | L | . |
Q | D | G | N | V | M | P | Q | L | G | L | G | V | W | Q | A | . |
. |
. |
. |
S | N | E | E | V | I | T | A | I | Q | K | A | L | E | V | G | Y | R | S | I | D | T | A | A | A | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
K | . |
N | E | E | G | V | G | K | A | L | K | N | A | S | V | N | R | E | E |
Template Known Secondary structure |   |
 |  |  |
| . | T | T | S |
|  |  |  | S | B |
|  |  |
|
| S |
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |
|
| G | G | G | . | . | . | . | . | . | . | . | . | T | . |
|  |  |  |  |  |  |  |  |  |  | S |
| S |
| G | G | G |
Template Predicted Secondary structure |   |
 |  |  |
| . |
|
|
|
|  |  |
|  |  |  |  |  |
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . |
| . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
7 | . | . | 10 | |
. | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | |
|
|
|
. | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | |
|
|
|
|
|
|
|
|
. | |
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . |
  |
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | I | I | A | S | K | V | S | G | P | S | R | N | N | D | K | G | I | R | P | D | Q | A | L | D | R | K | N | I | R | E | A | L | H | D | S | L | K | R | L | Q | T | D | Y | L | D | L | Y | Q | V | H | W | P | Q | R | P | T | N | C | F | G | K | L | G | Y | S | W | T | D | S | A | P | A | V | S | L | L | D | T | L |
Query Conservation |   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |
|
|   |
|   |
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|   |
|
|
|   |   |
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
Template Sequence |   |
L | F | I | T | T | K | L | W | N | D | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | K | R | P | R | E | A | L | L | D | S | L | K | K | L | Q | L | D | Y | I | D | L | Y | L | M | H | W | P | V | P | A | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | H | Y | V | E | A | W |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
| G | G | G | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
|  |  |  |  |  |  | S |
|
|
| T | T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
72 | . | . | . | . | . | . | . | 80 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 120 | . |
  |
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | A | L | A | E | Y | Q | R | A | G | K | I | R | Y | I | G | V | S | N | E | T | A | F | G | V | M | R | Y | L | H | L | A | D | K | H | D | L | P | R | I | V | T | I | Q | N | P | Y | S | L | L | N | R | S | F | E | V | G | L | A | E | V | S | Q | Y | E | G | V | E | L | L | A | Y | S | C | L | G | F | G | T | L |
Query Conservation |   |
  |   |
|   |   |
|   |   |   |
|   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |   |   |
|   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
K | G | M | I | E | L | Q | K | E | G | L | I | K | S | I | G | V | C | N | F | Q | I | H | H | L | Q | R | L | I | D | E | T | G | . |
. |
. |
. |
V | T | P | V | I | N | Q | I | E | L | H | P | L | M | Q | . |
. |
Q | R | Q | L | H | A | W | N | A | T | H | K | I | Q | T | E | S | W | S | P | L | A | Q | G | G | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |  |  |  | S | . | . | . | . |
|
|
| S |  |  |  |  |  |
| B | T | T | B |
| . | . |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  | S | T | T | T | T | T |
| T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
122 | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | |
|
|
|
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
|
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . |
  |
  |   |
242 | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | G | K | Y | L | N | G | A | K | P | A | G | A | R | N | T | L | F | S | R | F | T | R | Y | S | G | E | Q | T | Q | K | A | V | A | A | Y | V | D | I | A | R | R | H | G | L | D | P | A | Q | M | A | L | A | F | V | R | R | Q | P | F | V | A | S | T | L | L | G | A | T | T | M | D | Q | L | K | T | N | I | E | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |
|   |
|
|   |
|
|   |   |   |
|   |   |
|   |
|   |   |   |
|   |
|   |   |   |   |   |   |
|   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |
|   |   |   |   |
| . | . |
|
|   |
|   |   |   |   |   |   |
|   |
|
|
|   |   |
Template Sequence |   |
G | V | F | D | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | V | I | R | D | L | A | D | K | Y | G | K | T | P | A | Q | I | V | I | R | W | H | L | D | S | G | L | V | . |
. |
V | I | P | K | S | V | T | P | S | R | I | A | E | N | F | D | V |
Template Known Secondary structure |   |
T | T | T | T | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|  | . | . |  |
|
| B |
|
|
|  |  |  |  |  |  | T | T |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
196 | . | . | . | 200 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | |
|
. | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . |
  |
  |   |
322 | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | |
. | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
Query Sequence |   |
L | H | L | E | L | S | E | D | V | L | A | E | I | E | A | V | H | Q | V | Y | T | Y | . |
P | A | P |
Query Conservation |   |
  |   |   |   |
|   |   |
|   |   |   |   |
|
|   |
|   |   |   |   |   |   | . |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |
|
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
W | D | F | R | L | D | K | D | E | L | G | E | I | A | K | L | D | Q | G | K | R | L | G | P | D | P |
Template Known Secondary structure |   |
S | S |
|
|
|
|  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
| S |
|
| T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . |
  |