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Job DescriptionP31828
Confidence100.00%DateThu Jan 5 11:48:53 GMT 2012
Rank4Aligned Residues870
% Identity10%Templatec2fgeA_
PDB info PDB header:hydrolase, plant proteinChain: A: PDB Molecule:zinc metalloprotease (insulinase family); PDBTitle: crystal structure of presequence protease prep from2 arabidopsis thaliana
Resolution2.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   35....40.........50.........60.........70.........80.........90.........100.........110....
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Query Sequence  LITGQLDNGLRYMIYPHAHPKDQVNLWLQIHTGSLQEEDNELGVAHFVEHMMFNGTKTWPGNKVIETFESMGLRFGRDVN
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Template Sequence  ILFKHKKTGCEVXSVSNEDENKVFGV. . . . . . VFRTPPKDSTGIPHILQHSVLCGSRKYPVKEP. . FVELLKGSLHTFLN
Template Known Secondary structure  TTT


S
SS......


SSSS
TTS
BTTB
SS
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   38.40.........50.........60... ......70.........80.........90..... ....100.........
 
   115....120.........130.........140.........150........ .160.........170.......
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Query Sequence  AYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVD. . . . . . . . . . . . . . . . . AERGVITEEWRAHQDAKWR
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Template Conservation 
 
  
 
 
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Template Sequence  AFTYPDRTCYPVAST. . NTKDFYNLVDVYLDAVFFPKCVDDAHTFQQEGWHYELNDPSEDISYKGVVFNEXKGVYSQPDN
Template Known Secondary structure 

SSS..SSBGGGTSST

S
TTS


TTS
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   110.........120.... .....130.........140.........150.........160.........170.........180.......
 
   178.180.........190.........200.........210.........220.........230.........240.........250.......
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Query Sequence  TSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALALIKDNLSKLPANKAAEN
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Template Conservation                 
     
    
     
 
  

   
 
 
  


 

 
       
   
           
Template Sequence  ILGRIAQQALSPENTYGVDSGGDPKDIPNLTFEEFKEFHRQYYHPSNARIWFYGDDDPVHRLRVLSEYLDXFEASPSPNS
Template Known Secondary structure 
TTSGGGS
TT

TTTGGG

SSGGGSS
TT



S
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   188.190.........200.........210.........220.........230.........240.........250.........260.......
 
   258.260.........270..... ....280.........290.........300.........310.........320.........330
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Query Sequence  RVWPTKAENHLRFNIIND. . . . . . . KENRVNGIALYYRLPMVQVNDEQSFIEQAEWSMLVQLFNQRLQERIQSGELKTIS
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Template Conservation                                                        
  

     
 
   
         
Template Sequence  SKIKFQKLFSEPVRLVEKYPAGRDGDLKKKHXLCVNWLLSEKPLDLQTQLALGFLDHLXLGTPASPLRKILLESGLGEAL
Template Known Secondary structure  S







SS


SSS
GGG


SS


SSTTSTTS
S
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   268.270.........280.........290.........300.........310.........320.........330.........340.......
 
   331........340.........350.........360.........370.........380.........390.........400.........410
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Query Sequence  GGTARSVKIAPDYQSLFFRVNARDDNMQDAANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQAERDLRMLTSR
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Template Conservation   .              
                
   
  
   
     
                             
Template Sequence  V. SSGLSDELLQPQFGIGLKGVSEENVQKVEELIXDTLKKLAEEGFDNDAVEASXNTIEFSLRENNTGSFPRGLSLXLQS
Template Known Secondary structure 
.S

SSSS

GGG





TTS
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   348 .350.........360.........370.........380.........390.........400.........410.........420......
 
   411........420... ......430.........440.........450.........460.........470.........480......
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Query Sequence  LASSSLNNTPFLS. . . PEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNEVAAKKALSPAAILALEKEYAN.
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Template Conservation               
        
               
           
 
   
               
       
Template Sequence  ISKWIYDXDPFEPLKYTEPLKALKTRIAEEGSKAVFSPLIEKLILNNSHRVTIEXQPDPEKATQEEVEEKNILEKVKAAX
Template Known Secondary structure  TTTS
SSGGG


TTT


TTTS
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   427..430.........440.........450.........460.........470.........480.........490.........500......
 
   487..490.........500.........510.........520.........530.........540.........550....
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Query Sequence  . . . . . . . . . . . . KKLAAYVFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGEEQKLQIIAVSNKGD
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Template Conservation                                 
                     

  
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Template Sequence  TEEDLAELARATEELKLKQETPDPPEALRCVPSLNLGDIPKEPTYVPTEVGDINGVKVLRHDLFT. NDIIYTEVVFDIGS
Template Known Secondary structure 
TS


TTS



GGGS
SS





SSSS


.SS
TT
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   507..510.........520.........530.........540.........550.........560.........570. ........580.....
 
   555....560.........570.........580.........590.........600.... .....610.........620....
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Query Sequence  LSFPAQQKSLIALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMN. . . . . . . . . . TLLSVSARTNNPEPGFQLIN
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Template Conservation   ..       
 
    
   

   
   
   
       
                   
            
 

 
Template Sequence  L. . KHELLPLVPLFCQSLLEXGTKDLTFVQLNQLIGRKTGGISVYPLTSSVRGKDEPCSKIIVRGKSXAGRADDLFNLXN
Template Known Secondary structure  S..
TTTGGGS

SSS
SSTTGGG
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   586 ...590.........600.........610.........620.........630.........640.........650.........660...
 
   625....630.. .......640.........650.........660.........670... ......680.......
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Query Sequence  QRITHSTI. NDNIWASLQNAQIQALKTLDQRPAEKFAQQMYETRYADDRT. . . . . . . . . . . . . . . . KLLQENQIAQFTAA
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Template Conservation    
    
 
 
    
                   
                   
         
             
Template Sequence  CLLQEVQFTDQQRFKQFVSQSRARXENRLRGSGHGIAAARXDAXLNIAGWXSEQXGGLSYLEFLHTLEKKVDEDWEGISS
Template Known Secondary structure 

S


TT
S
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   664.....670.........680.........690.........700.........710.........720.........730.........740...
 
   688.690.........700.........710... ......720.........730.........740.........750.........760......
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Query Sequence  DALAADRQLFSSPADITFVIVGNVAE. DKLVALITRYLGSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKR
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Template Sequence  SLEEIRRSLL. ARNGCIVNXTADGKSLTNVEKSVAKFLDLLPEN. . PSGGLVTWDGRLPLRNEAIVIPTQVNYVGKAGNI
Template Known Secondary structure 
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STT

TS
SS..
SS
S











S
SSBG
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   744.....750... ......760.........770.........780...... ...790.........800.........810.........820
 
   767..770.........780.........790.........800.........810.........820.........830.........840......
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Query Sequence  YDSRTPVNLPTRMALDAFNVALAKDLRVNIREQASGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKR
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Template Sequence  YSTGYELDGSAYVISKHIS. . . NTWLWDRVRVS. GGAYGGFCDF. . . . DSHSGVFSYLSYRDP. NLLKTLDIYDGTGDFL
Template Known Secondary structure  GGGT



T...TTTTT.T

S....TTTTSBS.
ST
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   821........830......... 840.........850 .........860 .........870..... ....880.........890.
 
   847..850.........860.........870.........880.........890.........900.........910.........920......
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Query Sequence  LAKGISEQELNEYQQNVQRSLDIQQRSVQQLANTIVNSLIQYDDPAAWTEQEQLLKQMTVENVNTAVKQYLSHPVNTYTG
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Template Sequence  RGLDVDQETLTKAIIGTIGDV. DSYQLPDAKGYSSLLRHLLGVTDEERQRKREEILTTSLKDFKDFAQAIDVVRDKGVAV
Template Known Secondary structure  T



.T



TT

T


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   892.......900.........910.. .......920.........930.........940.........950.........960.........970
 
   927..930.
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Query Sequence  VLLPK
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Template Sequence  AVASA
Template Known Secondary structure 
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   971....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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