Job Description P25539 Confidence 98.74% Date Thu Jan 5 11:42:04 GMT 2012 Rank 48 Aligned Residues 145 % Identity 13% Template c3dg8B_ PDB info PDB header:oxidoreductase, transferase Chain: B: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate PDBTitle: quadruple mutant (n51i+c59r+s108n+i164l) plasmodium2 falciparum dihydrofolate reductase-thymidylate synthase3 (pfdhfr-ts) complexed with rjf670, nadph, and dump Resolution 2.58 Å

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		163	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.																								.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.				.	.	.	.	.	.	210	.	.	.	.	.	.
Predicted Secondary structure																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.	.
Query SS confidence																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.	.
Query Sequence		M	A	S	G	E	S	Q	W	I	T	S	P	Q	A	R	R	D	V	Q	L	L	R	A	Q	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	H	A	I	L	T	S	S	A	T	V	L	A	D	D	P	A	.	.	.	L	T	V	R	W	S	E	L	D	E	Q	T	Q
Query Conservation																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.	.
Alig confidence																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.	.					.	.	.	.	.	.	.	.	.
Template Conservation																																																																									.	.	.	.	.	.	.	.	.
Template Sequence		G	N	K	G	V	L	P	W	K	C	I	S	L	D	M	K	Y	F	R	A	V	T	T	Y	V	N	E	S	K	Y	E	K	L	K	Y	K	R	C	K	Y	L	P	N	S	K	K	L	Q	N	V	V	V	M	G	R	T	N	W	E	S	I	P	K	K	F	K	P	L	S	N	R	.	.	.	.	.	.	.	.	.
Template Known Secondary structure			B	T	T	B		S	S	S																		T	T	T	S								G	G	G						S															S		S	T	T		S		T	T		.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																																									.	.	.	.	.	.	.	.	.
Template SS confidence
		41	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.
		217	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	L	Y	P	Q	Q	N	L	R	Q	P	I	R	I	V	I	D	S	Q	N	R	V	T	P	V	H	R	I	V	Q	Q	P	G	E	T	W	F	A	R	T	Q	E	D	S	R	E	W	P	E	T	V	R	T	L	L	I	P	E	H	K	G	H	L	D	L	V	V	L	M	M	Q	L	G	K	Q	Q	I	N	S	I
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	I	N	V	I	L	S	R	T	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	K	K	E	D	F	D	E	D	V	Y	I	I	N	.	.	.	.	.	.	.	.	K	V	E	D	L	I	V	L	L	G	K	L	N	Y	Y	K	C
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.							S	S		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.		T	T	T	S		S	S	S				S	.	.	.	.	.	.	.	.	S	T	T								T	S
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.	.	.
Template SS confidence
													123	.	.	.	.	.	.	130	.																							.	.	.	.	.	.	.	.	140	.	.	.	.									.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.			.	.	.	360	.	.	.	.	.
Predicted Secondary structure																																																														.	.
Query SS confidence																																																														.	.
Query Sequence		W	V	E	A	G	P	T	L	A	G	A	L	L	Q	A	G	L	V	D	E	L	I	V	Y	I	A	P	K	L	L	G	S	D	A	R	G	L	C	T	L	P	G	L	E	K	L	A	D	A	P	Q	F	K	F	K	E	I	R	H	V	.	.	G	P	D	V	C	L	H	L	V
Query Conservation																																																														.	.
Alig confidence																															.	.	.	.	.	.	.	.																								.	.
Template Conservation																															.	.	.	.	.	.	.	.
Template Sequence		F	I	L	G	G	S	V	V	Y	Q	E	F	L	E	K	K	L	I	K	K	I	Y	F	T	R	I	N	S	T	.	.	.	.	.	.	.	.	Y	E	C	D	V	F	F	P	E	I	N	E	N	E	Y	Q	I	I	S	V	S	D	V	Y	T	S	N	N	T	T	L	D	F	I
Template Known Secondary structure																T	T			S											.	.	.	.	.	.	.	.				S								T	T	T													T	T
Template Predicted Secondary structure																															.	.	.	.	.	.	.	.
Template SS confidence
		162	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190									.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions