Job Description P25539 Confidence 99.01% Date Thu Jan 5 11:42:04 GMT 2012 Rank 43 Aligned Residues 125 % Identity 18% Template c2oipE_ PDB info PDB header:transferase, oxidoreductase Chain: E: PDB Molecule:chain a, crystal structure of dhfr; PDBTitle: crystal structure of the s290g active site mutant of ts-2 dhfr from cryptosporidium hominis Resolution 2.80 Å

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		145	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.							.	190	.	.	.	.	.	.	.	.	.	200	.	.	.		.	.	.	.	.	.	210	.	.	.	.	.	.	.
Predicted Secondary structure																																														.	.	.	.	.	.																.
Query SS confidence																																														.	.	.	.	.	.																.
Query Sequence		G	F	P	Y	I	Q	L	K	L	G	A	S	L	D	G	R	T	A	M	A	S	G	E	S	Q	W	I	T	S	P	Q	A	R	R	D	V	Q	L	L	R	A	Q	S	H	.	.	.	.	.	.	A	I	L	T	S	S	A	T	V	L	A	D	D	P	A	.	L	T	V	R	W	S	E	L	D	E	Q	T	Q	A
Query Conservation																																														.	.	.	.	.	.																.
Alig confidence																					.							.																		.	.	.	.	.	.																.					.	.	.	.	.	.	.	.	.	.
Template Conservation																					.							.																																												.	.	.	.	.	.	.	.	.	.
Template Sequence		E	K	N	V	S	I	V	V	A	A	S	V	L	S	S	G	I	G	I	.	N	G	Q	L	P	W	.	S	I	S	E	D	L	K	F	F	S	K	I	T	N	N	K	C	D	S	N	K	K	N	A	L	I	M	G	R	K	T	W	D	S	I	G	R	R	P	L	K	N	R	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure													T	T	T					B	.	T	T	B		S	S	.																	S		T	T	S															T	S				T	T		.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																					.							.																																												.	.	.	.	.	.	.	.	.	.
Template SS confidence
		3	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.		.	.	.	.	.	.		.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
		218	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.		.	.	.	.	.
Predicted Secondary structure																																																																												.
Query SS confidence																																																																												.
Query Sequence		L	Y	P	Q	Q	N	L	R	Q	P	I	R	I	V	I	D	S	Q	N	R	V	T	P	V	H	R	I	V	Q	Q	P	G	E	T	W	F	A	R	T	Q	E	D	S	R	E	W	P	E	T	V	R	T	L	L	I	P	E	H	K	G	H	L	D	L	V	V	L	M	M	Q	L	G	K	Q	.	Q	I	N	S	I
Query Conservation																																																																												.
Alig confidence		.	.	.	.	.	.	.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.	.	.													.
Template Conservation		.	.	.	.	.	.	.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	I	I	V	V	I	S	S	S	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	P	Q	D	E	A	D	P	N	V	V	V	F	R	.	.	.	.	.	.	.	.	N	L	E	D	S	I	E	N	L	M	N	D	D	S	I	E	N	I
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.							S	S	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.				T	T		T	T					S	.	.	.	.	.	.	.	.	S	T	T	G	G	G	G	T	T	T	T			S
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.	.	.
Template SS confidence
												71	.	.	.	.	.	.	.	.																							80	.	.	.	.	.	.	.	.	.	90	.	.									.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.
Predicted Secondary structure
Query SS confidence
Query Sequence		W	V	E	A	G	P	T	L	A	G	A	L	L	Q	A	G	L	V	D	E	L	I	V	Y	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	V	C	G	G	E	S	I	Y	R	D	A	L	K	D	N	F	V	D	R	I	Y	L	T	R
Template Known Secondary structure																T	T			S
Template Predicted Secondary structure
Template SS confidence
		111	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions