Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	Y	I	F	R	L	I	I	T	V	I	Y	S	I	L	V	C	V	F	G	S	I	Y	C	L	F	S	P	R	N	P	K	H	V	A	T	F	G	H	M	F	G	R	L	A	P	L	F	G	L	K	V	E	C	R	K	P	T	D
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	E	S	Y	G	N	A	I	Y	I	A	N	H	Q	N	N	Y	D	M	V	T	A	S	N	I	V	Q	P	P	T	V	T	V	G	K	K	S	L	L	W	I	P	F	F	G	Q	L	Y	W	L	T	G	N	L	L	I	D	R	N	N
Secondary structure
SS confidence
Disorder																																																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	T	K	A	H	G	T	I	A	E	V	V	N	H	F	K	K	R	R	I	S	I	W	M	F	P	E	G	T	R	S	R	G	R	G	L	L	P	F	K	T	G	A	F	H	A	A	I	A	A	G	V	P	I	I	P	V	C	V	S
Secondary structure
SS confidence
Disorder																																		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	T	S	N	K	I	N	L	N	R	L	H	N	G	L	V	I	V	E	M	L	P	P	I	D	V	S	Q	Y	G	K	D	Q	V	R	E	L	A	A	H	C	R	S	I	M	E	Q	K	I	A	E	L	D	K	E	V	A	E	R	E
Secondary structure
SS confidence
Disorder								?	?	?	?	?																		?	?																								?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.
Sequence		A	A	G	K	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1iuq chain A Region: 59 - 243 Aligned: 185 Modelled: 185 Confidence: 98.6% Identity: 16% Fold: Glycerol-3-phosphate (1)-acyltransferase Superfamily: Glycerol-3-phosphate (1)-acyltransferase Family: Glycerol-3-phosphate (1)-acyltransferase Phyre2 PDB 2ke4 chain A Region: 203 - 244 Aligned: 42 Modelled: 42 Confidence: 16.7% Identity: 26% PDB header:membrane protein Chain: A: PDB Molecule:cdc42-interacting protein 4; PDBTitle: the nmr structure of the tc10 and cdc42 interacting domain2 of cip4 Phyre2 PDB 1ybx chain A Region: 204 - 239 Aligned: 36 Modelled: 36 Confidence: 7.6% Identity: 17% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: conserved hypothetical protein cth-383 from clostridium thermocellum Phyre2 1 d1iuqa_ 2 c2ke4A_ 3 c1ybxA_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1iuqa_ 98.6 16 Fold:Glycerol-3-phosphate (1)-acyltransferase Superfamily:Glycerol-3-phosphate (1)-acyltransferase Family:Glycerol-3-phosphate (1)-acyltransferase 2 c2ke4A_ 16.7 26 PDB header:membrane protein Chain: A: PDB Molecule:cdc42-interacting protein 4; PDBTitle: the nmr structure of the tc10 and cdc42 interacting domain2 of cip4 3 c1ybxA_ 7.6 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: conserved hypothetical protein cth-383 from clostridium thermocellum

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0