|   |
40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | D | D | R | T | I | V | V | G | R | R | G | T | G | K | S | A | L | F | I | Q | L | N | E | H | W | K | K | D | K | K | I | L | I | L | S | F | S | P | D | D | S | Q | I | I | G | F | R | S | M | L | K | P | F | T | G | S | F | N | L | A | R | A | A | T | R | L | L | W | R | Y | A | M | L | M | E | I | A | S | Y |
Query Conservation |   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |
|   |   |
|   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
A | G | R | A | V | L | L | A | G | P | P | G | T | G | K | T | A | L | A | L | A | I | A | Q | E | L | G | S | K | V | P | F | C | P | M | V | G | S | E | V | Y | S | T | E | I | K | K | T | E | V | L | M | E | N | F | R | R | A | I | G | L | R | I | K | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T | T |
|  |  |  |  |  |
|
| T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  | G | G | G | G |
|
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
62 | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | S | S | H | Y | K | L | S | S | Q | I | S | S | E | T | L | L | N | E | H | L | K | K | W | N | S | A | Q | G | D | I | L | R | K | C | R | L | V | A | K | E | Y | L | D | E | N | N | P | E | E | S | I | G | D | L | Q | F | N | L | N | I | S | E | I | E | N | N | I | V | S | L | L | E | R | S | D | R | K | V | V |
Query Conservation |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|   |
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |
|
|   |
|
|   |   |
|   |   |
|
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | K | K | K | E | I | I | Q | D | V | T | L | H | D | L | D | V | A | G | E | I | N | K | V | V | N | K | Y | I | D | Q | G | I | A | E | L | V |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
127 | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
  |
  |   |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 270 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | L | M | D | K | L | D | E | A | Y | E | P | D | N | I | G | I | G | I | I | A | G | L | A | Y | A | S | I | E | L | N | Q | K | A | K | C | I | R | P | I | I | F | L | R | D | N | I | F | R | S | L | S | K | E | D | P | D | Y | S | R | N | I | . |
. |
. |
. |
. |
E | G | Q | V | I | R | L | H | W | D | W | A | Q |
Query Conservation |   |
|   |
|
|
|
|
|
|   |
|   |   |
|
|   |   |   |   |   |
|   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |
|   |
|
|   |   |
|   | . | . | . | . | . |
|
|   |   |
|   |
|   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | G | V | L | F | V | D | E | V | H | M | L | D | I | E | C | F | T | Y | L | H | R | A | L | . |
. |
. |
. |
. |
. |
E | S | S | I | A | P | I | V | I | F | A | S | N | R | G | N | C | V | I | R | G | T | E | D | I | T | S | P | H | G | I | P | L | D | L | L | D | R | V | M | I | I | R | T | M | L | Y | T | P | Q |
Template Known Secondary structure |   |
 |
|  |  |  |  |  |
| G | G | G |
| B |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | T | S | S | S |
|
|  |  |  |  |  |  |
|
| S |  |  |  |
| B | T | T | S | S |
|  |  |  | T | T |
|
|  |  |  |  | T | T |  |  |  |  |  |
|
|
|
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
296 | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . |
  |
  |   |
275 | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | |
320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | M | L | S | A | K | R | M | K | V | A | F | K | L | D | I | E | K | D | Q | R | V | W | D | R | C | T | A | D | D | L | K | G | R | N | G | F | K | R | C | L | Q | F | T | . |
L | Y | R | P | R | D | L | L | S | L | L | N | E | A | F | F | S | A | F | R | E | N | R | E | T | I | I | N | T | D | L | E | Y | A |
Query Conservation |   |
|   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |   |
|   |
|
|
|   |
|
| . |
|   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|
|   |   |
|
Template Sequence |   |
E | M | K | Q | I | I | K | I | R | A | Q | T | E | G | I | N | I | S | E | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | L | N | H | L | G | E | I | G | T | K | T | T | L | R | Y | S | V | Q | L | L | T | P | A | N | L | L | A | K | I | N | G | K | D | S | I | E | K | E | H | V | E | E | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| B |
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S | B |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . |
  |
  |   |
354 | . | . | . | |
. | . | 360 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | K | S | I | . |
S | M | A | R | L | E | D | L | W | K | E |
Query Conservation |   |
  |   |   |
| . |
|   |   |
|
|   |
|
|   |   |
|
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |
|
|   |   |   |
|   |
|
Template Sequence |   |
S | E | L | F | Y | D | A | K | S | S | A | K | I | L | A | D |
Template Known Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
434 | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . |
  |