|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | P | R | F | A | A | N | L | S | M | M | F | T | E | V | P | F | I | E | R | F | A | A | A | R | K | A | G | F | D | A | V | E | F | L | F | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | N | Y | S | T | L | Q | I | Q | K | Q | L | E | Q | N | H | L | T | L | A | L | F | N | T | A | P | G | D | I | N | A | G | E |
Query Conservation |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
Template Conservation |   |
  |   |
|
|
|   |   |   |   |   |   | . | . | . |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |   |   | . | . | . |   |
Template Sequence |   |
M | I | K | I | G | A | H | M | P | I | S | . |
. |
. |
K | G | F | D | R | V | P | Q | D | T | V | N | I | G | G | N | S | F | Q | I | F | P | H | N | A | R | S | W | S | A | K | L | P | S | D | E | A | A | T | K | F | K | R | E | M | K | K | H | G | I | D | W | E | N | A | F | C | H | S | G | Y | L | . |
. |
. |
I |
Template Known Secondary structure |   |
|
|
|  |  |  |  |
|
|
| T | . | . | . | T |
| G | G | G |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |
| S |
|
|
| S | S | S |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| G | G | G |  |  |  |  |
|
| T | T | . | . | . |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | |
|
|
. | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
|
. |
  |
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | G | L | S | A | L | P | G | R | E | H | E | A | H | A | D | I | D | L | A | L | E | Y | A | L | A | L | N | C | E | Q | V | H | V | M | A | G | V | V | P | A | G | E | D | A | E | R | Y | R | A | V | F | I | D | N | I | R | Y | A | A | D | R | F | A | P | H | G | K | R | I | L | V | E | A | L | S | P | G | V | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|
|   |
|   |
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   | . | . |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   | . |
Template Sequence |   |
N | L | A | S | P | K | D | D | I | W | Q | K | S | V | E | L | L | K | K | E | V | E | I | C | R | K | L | G | I | R | Y | L | N | I | H | P | G | S | H | L | G | T | . |
G | E | E | E | G | I | D | R | I | V | R | G | L | N | E | V | L | N | . |
. |
N | T | E | G | V | V | I | L | L | E | N | V | S | Q | K | G | . |
Template Known Secondary structure |   |
| T | T |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
|
|  |  |
| T | T | S | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | T |
|
| S |
|  |  |  |  |  |
|
|
|
|
| T | . |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
| . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
75 | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | |
|
. | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | |
  |
  |   |
151 | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | |
|
|
|
|
|
. | . | . | . | . | . | . | |
|
|
|
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | |
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . |  |  |  |  |  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
P | H | Y | L | F | S | S | Q | Y | Q | A | L | A | I | V | E | E | V | A | . |
R | D | N | V | F | I | Q | L | D | T | F | H | A | Q | K | V | D | G | N | L | T | . |
. |
. |
. |
. |
. |
H | L | I | R | D | Y | A | . |
. |
. |
. |
. |
G | K | Y | A | H | V | Q | I | A | G | L | P | D | . |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   | . | . | . | . | . |   |
|
|   |   |
|
|   |   |
|   |   |   | . | . | . | . | . | . | . | . |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
Template Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
. |
G | N | I | G | Y | K | L | E | Q | L | K | K | I | R | D | L | V | D | Q | R | D | R | V | A | I | T | Y | D | T | C | H | G | F | D | S | G | Y | D | I | T | K | K | E | G | V | E | A | L | L | N | E | I | E | S | L | F | G | L | E | R | L | K | M | I | H | L | N | D | S | K | Y | P | L | G | A | A | K | D | R |
Template Known Secondary structure |   |
. | T |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |
| S |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| G | G | G |  |  |  |  |  |  |
|  |  | S | S |
| T | T |
|
|
|
|
|
Template Predicted Secondary structure |   |
. |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
151 | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
  |
  |   |
211 | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | |
. | . | . | 240 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . |  |  |  |  |  | . | . | . | . | . |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | H | E | P | D | D | G | E | I | N | Y | P | W | L | F | R | L | F | D | E | V | G | Y | Q | G | W | . |
I | G | C | E | Y | . |
. |
. |
. |
. |
K | P | R | G | L | T | E | E | G | L | G | W | F | D | A | W |
Query Conservation |   |
  |   |   |   |
|   |
|   |
|
|   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|   | . |
|   |   |
|   | . | . | . | . | . |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
Template Sequence |   |
H | E | R | I | G | S | G | F | I | G | E | E | G | F | A | V | F | F | S | F | K | E | I | Q | E | V | P | W | I | L | E | T | P | G | G | N | E | E | H | A | E | D | I | K | K | V | F | E | I | I | E | K | F |
Template Known Secondary structure |   |
 |  |
| T | T | S | S | S | S |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  | T | S |
|  |  |  |
|
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . |
  |