Job Description Q46891 Confidence 93.65% Date Thu Jan 5 12:35:33 GMT 2012 Rank 60 Aligned Residues 187 % Identity 11% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		19	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.								.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
Predicted Secondary structure																									.	.	.	.	.	.	.
Query SS confidence																									.	.	.	.	.	.	.
Query Sequence		E	R	F	A	A	A	R	K	A	G	F	D	A	V	E	F	L	F	P	Y	N	Y	S	.	.	.	.	.	.	.	T	L	Q	I	Q	K	Q	L	E	Q	N	H	L	T	L	A	L	F	N	T	A	P	G	D	I	N	A	G	E	W	G	L	S	A	L	P	G	R	E	H	E	A	H	A	D	I	D	L	A	L
Query Conservation																									.	.	.	.	.	.	.
Alig confidence																									.	.	.	.	.	.	.																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	V	L	K	G	I	Q	K	F	P	G	I	N	Y	P	V	L	T	P	N	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	K	G	F
Template Known Secondary structure										T	T		S										T	T	T		G	G	G	T	T								S				T	T		B							S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		58	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.																									110	.	.	.
		92	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.								.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.
Predicted Secondary structure																																	.	.	.	.	.	.	.
Query SS confidence																																	.	.	.	.	.	.	.
Query Sequence		E	Y	A	L	A	L	N	C	E	Q	V	H	V	M	A	G	V	V	P	A	G	E	D	A	E	R	Y	R	A	V	F	.	.	.	.	.	.	.	I	D	N	I	R	Y	A	A	D	R	F	A	P	H	G	K	R	I	L	V	E	A	L	S	P	G	V	K	P	H	Y	L	F	S	S	Q	Y	Q	A	L	A	I
Query Conservation																																	.	.	.	.	.	.	.
Alig confidence																			.	.	.	.	.										.	.	.	.	.	.	.
Template Conservation																			.	.	.	.	.
Template Sequence		E	A	A	V	A	A	G	A	K	E	V	V	I	F	G	A	A	.	.	.	.	.	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	I	S	P	A	K	V	A	E	V
Template Known Secondary structure							T	T		S								S	.	.	.	.	.									T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	S
Template Predicted Secondary structure																			.	.	.	.	.
Template SS confidence
		114	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130						.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.
		165	.	.	.	.	170	.		.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200					.	.	.	.	.	.	.	.	.	210	.																					.	.	.	.
Predicted Secondary structure									.																														.	.	.	.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.					.	.	.	.
Query SS confidence									.																														.	.	.	.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.					.	.	.	.
Query Sequence		V	E	E	V	A	R	D	.	N	V	F	I	Q	L	D	T	F	H	A	Q	K	V	D	G	N	L	T	H	L	I	R	D	Y	A	G	K	Y	.	.	.	.	A	H	V	Q	I	A	G	L	P	D	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	H	E	P	D	.	.	.	.
Query Conservation									.																														.	.	.	.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.					.	.	.	.
Alig confidence									.																														.	.	.	.												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.					.	.	.	.
Template Conservation
Template Sequence		T	K	K	F	Y	S	M	G	C	Y	E	I	S	L	G	D	T	I	G	V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V	S	V	V	D	S	S	V	A	G	L	G	G	C	P	Y
Template Known Secondary structure								T	T		S							T	T																			S		G	G	G						B		T	T	S												T	T							B	T	T	S					T	T
Template Predicted Secondary structure
Template SS confidence
		189	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.
						216	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.
Predicted Secondary structure		.	.	.	.
Query SS confidence		.	.	.	.
Query Sequence		.	.	.	.	D	G	E	I	N	Y	P	W	L	F	R	L	F	D	E	V	G	Y	Q
Query Conservation		.	.	.	.
Alig confidence		.	.	.	.
Template Conservation
Template Sequence		A	Q	G	A	S	G	N	L	A	T	E	D	L	V	Y	M	L	E	G	L	G	I	H
Template Known Secondary structure		S	S	S				B		B											T	T		B
Template Predicted Secondary structure
Template SS confidence
		269	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions