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Job DescriptionP45549
Confidence100.00%DateThu Jan 5 12:03:06 GMT 2012
Rank21Aligned Residues245
% Identity19%Templatec2xrgA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor
Resolution3.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   3......10.........20.........30.........40.........50.........60...... ...70.... .....80
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Query Sequence  RFVVLVIDSFGVGAMKDVTLVRPQDAGANTCGHILSQLPHLQLPTLETLGLINALGYAPGDMQP. SDSATWGV. AELQHE
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Template Sequence  PLIIFSVDGFRAS. . . . . . . . . . . . . . . . . . . . . YMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYP
Template Known Secondary structure 
T

GG.....................GGGS
TTTSS
S


SS
S
S
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   164.....170...... ...180.........190.........200.........210.........220..
 
   81........90.........100....... ..110.........120.........130.........140.........150....
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Query Sequence  GGDTFMGHQEILGTRPLPPLRMPFRDV. . . . . . IDRVEQALVSAGWQVERRGDDLQFLWVNQAVAIGDNLEADLGQVYNI
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Template Sequence  ESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  S


SSTTTT
SSSSGGG
TTS

S

TTT

B
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   223......230.........240.........250.........260.........270.
 
   155....160.........170.........180.........190.........200.........210.........220.........230....
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Query Sequence  TANLSVISFDDAIKIGRIVREQVQVGRVITFGGLLTDSQRILDAAESKEGRFIGINAPRSGAYDNGFQVVHMGYGVDEKV
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   235....240.........250.........260.........270.........280.........290.........300...... ...310..
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Query Sequence  QVPQKLYEAGVPTVLVGKVADIVNNPYGVSWQNLVDSQRIMDITLNEFNTHPTAFICTNIQETDLAGHAEDV. . ARYAER
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . TFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNP
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TTS
TTS
TTT

S
TT
GGG
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   272.......280.........290.........300.........310.........320.......
 
   313......320........ .330.........340
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Query Sequence  LQVVDRNLARLVEAMQ. . . . . PDDCLVVMADHG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  LREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKYDPKTIIAALTC
Template Known Secondary structure  TT
TTT
S




SSSGGGT
S

TT
BS


TTSS
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   328.330.........340.........350.........360.........370.........380.........390.........400.......
 
   341........350. ........360.........370.....
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NDPTIGHSHHT. . REVVPVLVYQQGMIATQLGVRTTL
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Template Sequence  KKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRRWHVARKPFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFEN
Template Known Secondary structure 
STT

GGGS
GGG


SSTTS
S
TT
S





S
TT
GGG
B
SSSB
SS
B


G
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   414.....420.........430.........440.........450.........460.........470.........480.........490...
 
   376...380........ .390..... ....400...
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Query Sequence  SDVGATVCEFFRA. PPPQNGR. . SFLSSLRF
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Template Sequence  IELYNVMCDLLGLKPAPNNGTHGSLNHLLRT
Template Known Secondary structure  GGT



S
SS
TTTTGGGBSS
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   506...510.........520.........530......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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