|   |
116 | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 |
Predicted Secondary structure |   |
|  |  |
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | T | R | D | M | H | I | H | L | D | K | T | F | Y | G | G | P | W | R | S | L | N | R | P | A | G | T | T | I | Q | D | M | I | K | L | E | Q | K | M | L | P | E | L | . |
. |
. |
. |
. |
Q | P | Y | T | Q | E | R | A | E | K | L | I | D | L | L | Q | S | K | G | T | T | I | A | R | S | H | C | N | I | E | P | V |
Query Conservation |   |
|
|
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | G | I | D | P | H | T | H | L | D | M | P | F | G | G | T | V | T | A | D | D | . |
. |
. |
F | F | T | G | T | R | A | A | A | F | G | G | T | T | S | I | V | D | F | C | L | T | K | K | G | E | S | L | K | S | A | I | A | T | W | H | E | K | A | R | G | K | A | V | I | D | Y | G | F | H | L | M | I | A | E | A |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
| T | T |
|  |  | T | T |  |  |
| S |
|
| . | . | . |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
|
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| S | S |  |  |  |  |  |  |  |
| S |
|
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
53 | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
|
. | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . |
  |
  |   |
191 | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
Query Sequence |   |
S | G | L | K | N | L | Q | N | L | Q | A | V | L | A | R | R | Q | A | G | F | E | C | E | I | V | A | F | P | Q | H | G | L | L | L | S | K | S | E | P | L | M | R | E | A | M | Q | A | G | A | H | Y | V | G | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
N | D | Q | V | L | E | E | L | E | S | V | I | S | S | E | G | I | T | S | L | K | V | F | M | A | Y | K | N | V | F | Q | A | D | D | E | T | L | F | K | T | L | V | K | A | K | E | L | G | A | L | V | Q | V | H | A | E | N | G | D | V | L | D | Y | L | T | K | K | A | L | A | E | G | N | T | D | P | I | Y | H | A |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
|
|  |  |  |  |  | S |
| S | T | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S | T | T |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . |
  |
  |   |
247 | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | T | S | V | D | G | A | M | E | K | S | L | D | T | M | F | Q | I | A | L | D | Y | D | K | G | V | D | I | H | L | H | E | T | T | P | A | G | V | A | A | I | N | Y | M | V | E | T | V | E | K | T | P | Q | L | K | G | K | L | T | I | S | H | A | F | A | L | A | T | L | N | E | Q | Q | V | D | E | L | A | N | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|   |   |
| . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Y | T | R | P | P | E | A | E | G | E | A | T | G | R | A | I | A | L | T | A | L | A | G | S | Q | L | Y | V | V | H | V | S | C | . |
. |
. |
. |
. |
. |
. |
. |
A | S | A | V | Q | R | I | A | E | A | R | E | K | G | W | N | V | Y | G | E | T | C | P | Q | Y | L | A | L | D | V | S | I | M | D | Q | P | D | F | E |
Template Known Secondary structure |   |
 | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |
| S |
|
| S | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |
|  |  |  |  |  |
|
| G | G | G | G |
|
| S | S | S | G |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . |
  |
  |   |
327 | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | V | V | Q | Q | I | S | I | A | S | T | V | P | I | G | T | L | H | M | P | L | K | Q | L | H | D | K | G | V | K | V | M | T | G | T | D | S | V | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | H | W | S | P | Y | G | L | G | D | M | L | E | K | A | N | L | Y | A | Q | L | Y | I | R | P | N | E | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   | . | . |   |   |
|   |   |   |
|   |   |
|   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|
Template Sequence |   |
G | A | K | Y | V | W | S | P | P | L | R | E | K | W | N | Q | . |
. |
E | V | L | W | S | A | L | K | N | G | I | L | Q | T | V | G | S | D | H | C | P | F | N | F | R | G | Q | K | E | L | G | R | G | D | F | T | K | I | P | N | G | G | P | L | I | E | D | R | L | T | I | L | Y | S | E | G | V | R | Q | G | R | I |
Template Known Secondary structure |   |
G | G | G | G |
|
| S | S |
|
|
|
| T | T |  |  | . | . |  |  |  |  |  |  |  |  | T | T | S | S |
|  |  |
|
|
| B |
|
|
|
| T | T | T | T | G | G | G | G | T | T |
| G | G | G | S |
|
|
| B |
|
| T | T | T |  |  |  |  |  |  |  |  | T | T | T | T | T | S | S |
Template Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
282 | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | |
|
. | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . |
  |
  |   |
394 | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | |
. | 410 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | L | S | R | S | L | F | L | A | T | G | D | V | L | P | . |
L | N | E | K | G | E | R | V | W |
Query Conservation |   |
  |
|   |   |
|
|   |   |   |
|   |   |
|
|   | . |
|   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|
|
Template Sequence |   |
S | L | N | Q | F | V | D | I | S | S | T | K | A | A | K | L | F | G | M | F | P | R | K | G | T |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  | T |  |  |  |  |  |  | T | T |
| T | T | T | S |
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . |
  |