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Job DescriptionP08394
Confidence99.89%DateThu Jan 5 11:01:26 GMT 2012
Rank18Aligned Residues373
% Identity27%Templatec2wjyA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:regulator of nonsense transcripts 1; PDBTitle: crystal structure of the complex between human nonsense2 mediated decay factors upf1 and upf2 orthorhombic form
Resolution2.50 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   16...20.........30.........40.........50.........60.........70........ .80.........
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Query Sequence  QGERLIEASAGTGKTFTIAALYLRLLLGLGGSAAFPRPLTVEELLVVTFTEAATAELRGRIRS. . . . . . NIHELRIACLR
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Template Sequence  RPLSLIQGPPGTGKTVTSATIVYHLA. . . . . . . . . . . RQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAID
Template Known Secondary structure  SS

TTS
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SS
SSTTT




GGGGG

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   485....490.........500.........510 .........520.........530.........540.........550...
 
   90.........100.........110.........120.........130.........140.........150.........160.........
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Query Sequence  ETTDNPLYERLLEEIDDKAQAAQWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLRYQACADFWR
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Template Sequence  SPVSFLALHNQIRNMDSMPE. LQKLQQLKDETGELSSADEKRYRALKRTAE. . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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TTGGGBT
TT
.TTTS


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   554.....560.........570... ......580.........590.........600...
 
   170.........180.........190.........200.........210.........220.........230.........240.........
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Query Sequence  RHCYPLPREIAQVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETLASRHAQIVARIDTVKQQWRDAVGELDALIES
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   250.........260.........270.........280.........290.........300.........310.........320.........
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Query Sequence  SGIDRRKFNRSNQAKWIDKISAWAEEETNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIDQLLAEPLSIRDLVIT
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   330.........340.........350.........360.........370.........380...... ...390.........400........
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Query Sequence  RALAEIRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEF. QDTDPQQYRIFRRIWHHQPETA
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . RELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVV. . . . . LGAKQ
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STGGGG
TTTTT


STTGGGS
T.....TTBS
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   604.....610.........620.........630.........640.........650. .....
 
   409410.........420... ......430.........440.........450.........460.........470.........480.
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Query Sequence  LLLIGDPKQAIYAFR. . . . . . . GADIFTYMKARSEVHAHYTLDTNWRSAPGMVNSVNKLFSQTDDAFMFREIPFIPVKSA
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Template Sequence  LILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYE. . . . . . . GSLQNGVTAAD
Template Known Secondary structure 
TTS






TTTTS
TT





SS
ST.......T

SS
SGG
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   657..660.........670.........680.........690.........700.........710........ .720.........
 
   482.......490.........500.........510..... ....520.........530.........540.........550........
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Query Sequence  GKNQALRFVFKGETQPAMKMWLMEGESCGVGDYQ. . . STMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLV
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Template Sequence  RVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAG. . . . . . . . . . . . . . . AKPDQIGIIT
Template Known Secondary structure  GS
TT




SSTTS






SSBS

TT...............

GGG
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   730.........740.........750.........760.........770.........780.... .....790....
 
   559560.........570.........580.........590.........600.........610.........620.........630........
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Query Sequence  RSRQEAAQVRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLNALDIETLNNDEHAW
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Template Sequence  PYEGQRSYLVQYMQFSGSLHTKLYQ. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  S

SS
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   795....800.........810.........
 
   639640.........650.........660.........670.........680.........690.........700.........710........
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Query Sequence  DVVVEEFDGYRQIWRKRGVMPMLRALMSARNIAENLLATAGGERRLTDILHISELLQEAGTQLESEHALVRWLSQHILEP
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   719720.........730.........740.........750.........760.........770.........780.........790........
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Query Sequence  DSNASSQQMRLESDKHLVQIVTIHKSKGLEYPLVWLPFITNFRVQEQAFYHDRHSFEAVLDLNAAPESVDLAEAERLAED
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Template Sequence  . . . . . . . . . . . . . . . . EVEIASVDAFQGREKDFIILSCVRANEHQGIGFLND. . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ................TS
GGGGTT





S




GGGT
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   820.........830.........840.........850.....
 
   799800.........810.......
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Query Sequence  LRLLYVALTRSVWHCSLGV
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Template Sequence  PRRLNVALTRARYGVIIVG
Template Known Secondary structure  TS
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   856...860.........870....
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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