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Job DescriptionP08394
Confidence99.90%DateThu Jan 5 11:01:26 GMT 2012
Rank17Aligned Residues376
% Identity27%Templatec2gk7A_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:regulator of nonsense transcripts 1; PDBTitle: structural and functional insights into the human upf1 helicase core
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   16...20.........30.........40.........50.........60.........70.........80.........90.....
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Query Sequence  QGERLIEASAGTGKTFTIAALYLRLLLGLGGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHELRIACLRETTDNP
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Template Sequence  RPLSLIQGPPGTGKTVTSATIVYHLARQGN. . . . . . . . . . . GPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAID
Template Known Secondary structure  SS

TTS
T
S...........S
SSTTT




GGGTT

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   485....490.........500.........510.... .....520.........530.........540.........550...
 
   96...100.........110.........120.........130.........140.........150.........160.........170.....
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Query Sequence  LYERLLEEIDDKAQAAQWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLRYQACADFWRRHCYPL
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Template Conservation         .............................................................            
Template Sequence  SPVSFLA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LHNQIRNMDSMP
Template Known Secondary structure 
TTGGGB.............................................................T
TT
T
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   554.....560 .........570..
 
   176...180.........190.........200.........210.........220.........230.........240.........250.....
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Query Sequence  PREIAQVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETLASRHAQIVARIDTVKQQWRDAVGELDALIESSGIDRR
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Template Conservation                             .....................................................
Template Sequence  ELQKLQQLKDESSADEKRYRALKRTAE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  T



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   573......580.........590.........
 
   256...260.........270.........280.........290.........300.........310.........320.........330.....
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Query Sequence  KFNRSNQAKWIDKISAWAEEETNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIDQLLAEPLSIRDLVITRALAEI
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   336...340.........350.........360.........370.........380.........390.........400.........410.....
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Query Sequence  RETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEFQDTDPQQYRIFRRIWHHQPETALLLIGDP
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Template Sequence  . . . . . . . . . . . . . . . . RELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPEC. MVPVV. . . LGAKQLILVGDH
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STGGGG
GGGTT


SSSGGGS
.T...TTBS
T
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   604.....610.........620.........630.........640...... ...650. ........660...
 
   416...420. ........430.........440.........450.........460.........470.........480........
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Query Sequence  KQAIYA. . . . . . . FRGADIFTYMKARSEVHAHYTLDTNWRSAPGMVNSVNKLFSQTDDAFMFREIPFIPVKSAGKNQALR
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Template Sequence  CQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYE. . . . . . . GSLQNGVTAADRVKKGFD
Template Known Secondary structure  TS




S
TTS

TT





SS
ST.......T

SS
TGGGS
TT

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   664.....670.........680.........690.........700.........710........ .720.........730......
 
   489490.........500.........510... ......520.........530.........540.........550.........560.....
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Query Sequence  FVFKGETQPAMKMWLMEGESCGVGD. . . YQSTMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLVRSRQEAA
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Template Sequence  FQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAG. . . . . . . . . . . . . . . AKPDQIGIITPYEGQRS
Template Known Secondary structure 


SSSS
S




SSBS
T...............

GGG
S
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   737..740.........750.........760.........770.........780.... .....790.........800.
 
   566...570.........580.........590.........600.........610.........620.........630.........640.....
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Query Sequence  QVRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLNALDIETLNNDEHAWDVVVEEF
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Template Conservation   
   
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Template Sequence  YLVQYMQFSGSLHTKLYQ. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  S
SS
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   802.......810.........
 
   646...650.........660.........670.........680.........690.........700.........710.........720.....
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Query Sequence  DGYRQIWRKRGVMPMLRALMSARNIAENLLATAGGERRLTDILHISELLQEAGTQLESEHALVRWLSQHILEPDSNASSQ
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   726...730.........740.........750.........760.........770.........780.........790.........800.....
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Query Sequence  QMRLESDKHLVQIVTIHKSKGLEYPLVWLPFITNFRVQEQAFYHDRHSFEAVLDLNAAPESVDLAEAERLAEDLRLLYVA
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Template Sequence  . . . . . . . . . EVEIASVDAFQGREKDFIILSCVRANEHQGIGFLND. . . . . . . . . . . . . . . . . . . . . . . . . . . . PRRLNVA
Template Known Secondary structure  .........TS
SGGGTT





S
S


STTS
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   820.........830.........840.........850..... ....860..
 
   806...810.......
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Query Sequence  LTRSVWHCSLGV
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Template Sequence  LTRARYGVIIVG
Template Known Secondary structure  TS
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   863......870....
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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