|   |
2 | . | . | . | . | . | . | . | 10 | . | . | |
. | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | |
|
|
. | . | . | . | . | . | . | . | 70 | . | . | |
|
|
|
. |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . |  |  |  |  |
|
|
|  |  |  |  | . | . | . | . |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
Query Sequence |   |
S | L | P | M | L | Q | V | A | L | D | N | . |
Q | T | M | D | S | A | Y | E | T | T | R | L | I | A | E | E | V | D | I | I | E | V | G | T | I | L | C | V | G | E | G | V | R | A | V | R | D | L | K | A | L | Y | P | H | K | I | V | L | A | . |
. |
. |
D | A | K | I | A | D | A | G | K | I | L | . |
. |
. |
. |
S |
Query Conservation |   |
  |   |
|   |
|   |
|
|
|
|   | . |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   | . | . | . |
|   |
|   |   |
|   |   |   |   |   | . | . | . | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
Template Conservation |   |
|
|   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . |   |   |   |
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |   |   |   |   |
|
|   |
|
|
|
|
|   |
Template Sequence |   |
R | K | P | I | I | A | G | N | W | K | M | N | G | T | L | A | E | A | V | Q | F | V | E | D | V | K | G | H | V | P | P | A | D | . |
E | V | I | S | V | V | C | A | P | F | L | F | L | D | R | L | V | Q | A | A | D | G | T | D | L | K | I | G | A | Q | T | M | H | F | A | D | Q | G | A | Y | T | G | E | V | S | P |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |
|
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | T | T | S |
|
| T | T | . | T |
|  |  |  |  |  |  |
| G | G | G |  |  |  |  |  |  |  |  | T | T | S | S |  |  |  |  |  | S |
|
|
| S | S | S | S | S | S |
| T | T |
|
|
|  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
  |
  |   |
74 | . | . | . | . | . | 80 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
R | M | C | F | E | A | N | A | D | W | V | T | V | . |
. |
. |
. |
. |
. |
. |
I | C | C | A | D | I | N | T | A | K | G | A | L | D | V | A | K | E | F | N | G | D | V | Q | I | E | L | T | G | Y | W | T | W | E | Q | A | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | W | R | D | A |
Query Conservation |   |
  |   |   |   |   |   |
|
|
|   |
|   |
| . | . | . | . | . | . | . |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|   |
|   |   |   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|
|
|   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |
|
|
| . |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
V | M | L | K | D | L | G | V | T | Y | V | I | L | G | H | S | E | R | R | Q | M | F | A | E | T | D | E | T | V | N | K | K | V | L | A | A | F | T | R | G | L | I | P | I | I | . |
C | C | G | E | S | L | E | E | R | E | A | G | Q | T | N | A | V | V | A | S | Q | V | E | K | A | L | A | G | L | T | P | E | Q | V |
Template Known Secondary structure |   |
 |  |  |  |  |  | T |
|
|  |  |  |  | S |
|  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  | . |  |  |
|
|
|  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  | . |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | |
. | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
129 | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
. | . | . | . | . | . | 190 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | I | G | Q | V | V | Y | H | R | S | R | D | A | Q | A | A | G | V | A | W | G | E | A | D | I | T | A | I | K | R | L | S | D | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | F | K | V | T | V | T | G | G | L | A | L | E | D | L | P | L | F | K | G | I | . |
P | I | H | V | F | I | A | G | R | S | I | R | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   | . |
|
|
|   |
|
|
|
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |
|   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|
|   |
|
|
|   |
|
|
|   |
Template Sequence |   |
K | Q | A | V | I | A | Y | E | P | I | W | A | I | G | T | G | K | S | S | T | P | E | D | A | N | S | V | C | G | H | I | R | S | V | V | S | R | L | F | G | P | E | A | A | E | A | I | R | I | Q | Y | G | G | S | V | K | P | D | N | I | R | D | F | L | A | Q | Q | Q | I | D | G | A | L | V | G | G | A | S | L | E |
Template Known Secondary structure |   |
T | T |
|  |  |  |  |
|
| G | G | G | T | T | T | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  | T | T | S |  |  |  |  |  | S | S |
|
| T | T | T |  |  |  |  |  | T | S | T | T |
|
|  |  |  |  | S | G | G | G | S | S |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
  |
  |   |
197 | . | . | 200 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | S | P | V | E | A | A | R |
Query Conservation |   |
|   |
|
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|
|   |
Template Sequence |   |
P | A | S | F | L | Q | L | V | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
  |   |
239 | 240 | . | . | . | . | . | . | . |
  |