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Job DescriptionP39304
Confidence97.62%DateThu Jan 5 11:59:08 GMT 2012
Rank187Aligned Residues166
% Identity13%Templatec2fptA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   47..50.........60...... ...70.........80 .........90. ........100.....
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Query Sequence  VRDLKALYPHKIVLADAKIA. . . . DAGKILSRMCFEAN. . ADWVTVICCAD. . . . . . . . . . INTAKGALDVAKEF. . . . .
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Template Sequence  QKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLR
Template Known Secondary structure  TT




TT
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TTSTTSGGGGSTS
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   166...170.........180.........190.........200.........210.........220.........230.........240.....
 
   106...110.........120. ........130.........140........ .150.........160.
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Query Sequence  . . . NGDVQIELTGYWTWEQ. . . . AQQWRDAGIGQVVYHRSRDAQAAGVAW. . . . . . . . . . . . . . . . . GEADITAIKRLSD
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Template Sequence  RVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQ
Template Known Secondary structure  GGG


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   246...250.........260.........270.........280.........290.........300.........310.........320.....
 
   162.......170.. .......180.........190.........200.........210....
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Query Sequence  MGFKVTVTGGL. ALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAEL
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Template Sequence  GRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWG. . PPVVGKVKRELEAL
Template Known Secondary structure  T
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   326...330.........340.........350.........360... ......370.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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