Job Description P39304 Confidence 97.20% Date Thu Jan 5 11:59:08 GMT 2012 Rank 207 Aligned Residues 169 % Identity 12% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		14	.	.	.	.	.	20	.	.	.	.	.		.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.			.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90
Predicted Secondary structure														.																						.	.
Query SS confidence														.																						.	.
Query Sequence		T	M	D	S	A	Y	E	T	T	R	L	I	.	A	E	E	V	D	I	I	E	V	G	T	I	L	C	V	G	E	G	V	R	A	.	.	V	R	D	L	K	A	L	Y	P	H	K	I	V	L	A	D	A	K	I	A	D	A	G	K	I	L	S	R	M	C	F	E	A	N	A	D	W	V	T	V	I	C	C	A
Query Conservation														.																						.	.
Alig confidence														.																						.	.																											.
Template Conservation																																																																.
Template Sequence		S	T	P	V	K	I	K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	V	L	K	G	I	Q	K	F	P	G	I	N	Y	P	V	L	T	P	N	L	K	G	F	.	E	A	A	V	A	A	G	A	K	E	V	V	I	F	G	A	A
Template Known Secondary structure																T	T		S										T	T	T		G	G	G	T	T								S				T	T		B							S					.						T	T		S								S
Template Predicted Secondary structure																																																																.
Template SS confidence
		52	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.		.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130
		91	.																.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.													.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.
Predicted Secondary structure				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		D	I	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	T	A	K	G	A	L	D	V	A	K	E	F	N	G	D	V	Q	I	E	L	T	G	Y	W	T	.	.	.	.	.	.	.	.	.	.	.	.	W	E	Q	A	Q	Q	W	R	D	A	G	I	G	Q	V	V	Y	H	R	S	R	D	A	Q	A
Query Conservation				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.	.	.	.	.																		.	.	.	.	.
Template Conservation																																																																										.	.	.	.	.
Template Sequence		S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C	Y	E	I	S	L	.	.	.	.	.	G	D	T
Template Known Secondary structure										T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	S																T	T		S					.	.	.	.	.			T
Template Predicted Secondary structure																																																																										.	.	.	.	.
Template SS confidence
		131	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.						.	.	.
		144	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170							.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.
Predicted Secondary structure																													.	.	.	.	.	.
Query SS confidence																													.	.	.	.	.	.
Query Sequence		A	G	V	A	W	G	E	A	D	I	T	A	I	K	R	L	S	D	M	G	F	K	V	T	V	T	G	.	.	.	.	.	.	G	L	A	L	E	D	L	P	L	F	K	G	I	P	I	H	V	F
Query Conservation																													.	.	.	.	.	.
Alig confidence																													.	.	.	.	.	.
Template Conservation
Template Sequence		I	G	V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V	S	V	V
Template Known Secondary structure		T																			S		G	G	G						B		T	T	S												T	T
Template Predicted Secondary structure
Template SS confidence
		206	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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