Secondary structure and disorder prediction

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Sequence		M	L	T	K	Y	A	L	A	A	V	I	V	L	C	L	T	V	L	G	F	T	L	L	V	G	D	S	L	C	E	F	T	V	K	E	R	N	I	E	F	K	A	V	L	A	Y	E	P	K	K
Secondary structure
SS confidence
Disorder		?	?	?																																											?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2ii8 chain F Region: 26 - 49 Aligned: 24 Modelled: 24 Confidence: 30.6% Identity: 13% PDB header:signaling protein Chain: F: PDB Molecule:anabaena sensory rhodopsin transducer protein; PDBTitle: anabaena sensory rhodopsin transducer Phyre2 PDB 1nc7 chain A Region: 25 - 49 Aligned: 25 Modelled: 25 Confidence: 29.4% Identity: 16% Fold: Hypothetical protein TM1070 Superfamily: Hypothetical protein TM1070 Family: Hypothetical protein TM1070 Phyre2 PDB 2wj8 chain N Region: 8 - 21 Aligned: 14 Modelled: 14 Confidence: 13.2% Identity: 36% PDB header:rna binding protein/rna Chain: N: PDB Molecule:nucleoprotein; PDBTitle: respiratory syncitial virus ribonucleoprotein Phyre2 PDB 3b8e chain B Region: 5 - 18 Aligned: 14 Modelled: 14 Confidence: 12.8% Identity: 21% PDB header:hydrolase/transport protein Chain: B: PDB Molecule:sodium/potassium-transporting atpase subunit PDBTitle: crystal structure of the sodium-potassium pump Phyre2 PDB 3ixz chain B Region: 5 - 22 Aligned: 18 Modelled: 18 Confidence: 12.3% Identity: 28% PDB header:hydrolase Chain: B: PDB Molecule:potassium-transporting atpase subunit beta; PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride Phyre2 PDB 1xme chain C domain 1 Region: 4 - 24 Aligned: 21 Modelled: 21 Confidence: 9.4% Identity: 57% Fold: Single transmembrane helix Superfamily: Bacterial ba3 type cytochrome c oxidase subunit IIa Family: Bacterial ba3 type cytochrome c oxidase subunit IIa Phyre2 PDB 2krx chain A Region: 25 - 39 Aligned: 15 Modelled: 15 Confidence: 7.6% Identity: 27% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:asl3597 protein; PDBTitle: solution nmr structure of asl3597 from nostoc sp. pcc7120. northeast2 structural genomics consortium target id nsr244. Phyre2 PDB 3arc chain L Region: 9 - 24 Aligned: 16 Modelled: 16 Confidence: 7.0% Identity: 13% PDB header:electron transport, photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom2 resolution Phyre2 PDB 1zll chain E Region: 10 - 23 Aligned: 14 Modelled: 14 Confidence: 6.8% Identity: 21% PDB header:membrane protein/signaling protein Chain: E: PDB Molecule:cardiac phospholamban; PDBTitle: nmr structure of unphosphorylated human phospholamban2 pentamer Phyre2 1 c2ii8F_ 2 d1nc7a_ 3 c2wj8N_ 4 c3b8eB_ 5 c3ixzB_ 6 d1xmec1 7 c2krxA_ 8 c3arcl_ 9 c1zllE_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2ii8F_ 30.6 13 PDB header:signaling protein Chain: F: PDB Molecule:anabaena sensory rhodopsin transducer protein; PDBTitle: anabaena sensory rhodopsin transducer 2 d1nc7a_ 29.4 16 Fold:Hypothetical protein TM1070 Superfamily:Hypothetical protein TM1070 Family:Hypothetical protein TM1070 3 c2wj8N_ 13.2 36 PDB header:rna binding protein/rna Chain: N: PDB Molecule:nucleoprotein; PDBTitle: respiratory syncitial virus ribonucleoprotein 4 c3b8eB_ 12.8 21 PDB header:hydrolase/transport protein Chain: B: PDB Molecule:sodium/potassium-transporting atpase subunit PDBTitle: crystal structure of the sodium-potassium pump 5 c3ixzB_ 12.3 28 PDB header:hydrolase Chain: B: PDB Molecule:potassium-transporting atpase subunit beta; PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride 6 d1xmec1 9.4 57 Fold:Single transmembrane helix Superfamily:Bacterial ba3 type cytochrome c oxidase subunit IIa Family:Bacterial ba3 type cytochrome c oxidase subunit IIa 7 c2krxA_ 7.6 27 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:asl3597 protein; PDBTitle: solution nmr structure of asl3597 from nostoc sp. pcc7120. northeast2 structural genomics consortium target id nsr244. 8 c3arcl_ 7.0 13 PDB header:electron transport, photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom2 resolution 9 c1zllE_ 6.8 21 PDB header:membrane protein/signaling protein Chain: E: PDB Molecule:cardiac phospholamban; PDBTitle: nmr structure of unphosphorylated human phospholamban2 pentamer

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0