|   |
225 | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | |
|
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | V | A | W | L | E | S | N | E | T | S | C | I | L | Y | T | S | G | T | T | G | K | P | K | G | V | Q | R | D | V | G | G | Y | A | V | A | L | A | T | S | M | D | T | I | F | . |
. |
G | G | K | A | G | S | V | F | F | C | A | S | D | I | G | W | V | V | G | H | S | Y | I | V | Y | A | P | L | L | A | G | M | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|
|
|
|
|
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
N | Y | P | F | G | L | V | A | G | D | X | K | R | D | G | V | R | I | H | S | S | N | P | T | V | I | V | H | S | Q | H | D | L | D | S | W | A | N | L | V | A | R | C | L | Y | X | V | G | I | R | K | T | D | V | F | Q | N | S | S | G | Y | G | X | F | T | G | G | L | G | F | Q | Y | G | A | E | R | L | G | C | L |
Template Known Secondary structure |   |
T | T | T | T | T | T |
|
| S |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | S |  |  |  |  |
| S |
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
73 | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
  |
  |   |
303 | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | I | V | Y | E | G | L | P | T | W | P | D | C | G | V | W | W | T | I | V | E | K | Y | Q | V | S | R | M | F | S | A | P | T | A | I | R | V | L | K | K | F | P | T | A | E | I | R | K | H | D | L | S | S | L | E | V | L | Y | L | A | G | E | P | L | D | E | P | T | A | S | W | V | S | N | T | L | D | V | P | V |
Query Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
Template Sequence |   |
T | V | P | A | A | A | G | . |
. |
. |
. |
N | S | K | R | Q | I | K | F | I | S | D | F | K | T | T | A | L | H | A | I | P | S | Y | A | I | R | L | A | E | V | F | Q | E | E | G | I | D | P | R | E | T | T | L | K | T | L | V | I | G | A | E | P | H | T | D | E | Q | R | R | K | I | E | R | X | L | N | V | K | A |
Template Known Secondary structure |   |
 |  |
|
|
| S |
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | S | S | S |
|
|  |  |  |  |  | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | S |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
158 | . | 160 | . | . | . | . | |
|
|
|
. | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . |
  |
  |   |
383 | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | D | N | Y | W | Q | T | E | S | G | W | P | I | M | A | I | A | R | G | L | D | D | R | P | T | R | L | G | S | P | G | V | P | M | Y | G | Y | N | V | Q | L | L | N | E | V | T | G | E | P | C | G | V | N | E | K | G | M | L | V | V | E | G | P | L | P | P | G | C | I | Q | T | I | W | G | D | D | G | R | F | V |
Query Conservation |   |
  |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |   |   | . | . | . |   |   |   |   |
|   |   |
|
|   |   |   | . |
Template Sequence |   |
Y | N | S | F | G | X | T | E | X | N | G | P | G | V | A | F | E | C | Q | . |
. |
. |
. |
. |
. |
E | Q | N | G | X | H | F | W | E | D | C | Y | L | V | E | I | I | D | P | E | T | G | E | P | V | P | E | G | E | I | G | E | L | V | L | T | T | L | D | . |
. |
. |
R | E | X | X | P | L | I | R | Y | R | T | R | . |
Template Known Secondary structure |   |
 |  |  |  |  |  | G | G | G | T |  |  |  |  |  |  |  |
| T | . | . | . | . | . | . | T |
| S | S |  |  |  |
| T | T | T |  |  |  |  |  |  |
| T | T | T |
| S | B |
| S | T | T |
|
|  |  |  |  |  |  |  | S | S | . | . | . |
|
| S | S |
|
|
| S |  |  |  |  | . |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
234 | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | |
|
|
. | . | . | . | . | . | . | . | 300 | . | . | . | |
  |
  |   |
463 | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | T | Y | W | S | L | F | S | R | P | V | Y | A | T | F | D | W | G | I | R | D | A | D | G | Y | H | F | I | L | G | R | T | D | D | V | I | N | V | A | G | H | R | L | G | T | R | E | I | E | E | S | I | S | S | H | P | G | V | A | E | V | A | V | V | G | V | K | D | A | L | K | G | Q | V | A | V | A | F | V | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |
|
|   |
|   |
|   |
|
|   |
|
|   |
|
|   |   |
|   |   |
|   |   |   |
|
|
|   |   |
|   |   |   |
|   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
D | L | T | R | I | L | P | G | K | C | P | C | G | R | T | H | L | R | I | D | R | I | K | G | R | S | D | D | X | F | I | I | K | G | V | N | I | F | P | X | Q | V | E | K | I | L | V | Q | F | P | E | L | G | S | N | Y | L | I | T | L | E | T | N | Q | D | E | X | I | V | E | V | E | L | S |
Template Known Secondary structure |   |
. | . | . | . | . | . |  |  |  |
|  |  |
| S |
|
| T | T |
|
|
| S |
|  |  |
|
|
|
|  |  | S | T | T |
|  |  |  | T | T |  |  |  |
|  |  |  |  |  |  |  |  | T | T |
| T | T |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
304 | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . |
  |
  |   |
543 | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | |
. | . | . | . | . | 580 | . | . | . | |
|
. | . | . | . | . | . | 590 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . |
|
|
|  |  |  |  |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | K | E | S | D | S | L | E | D | R | D | V | A | H | S | Q | E | K | A | I | M | A | L | V | D | S | Q | I | G | N | F | G | . |
R | P | A | H | V | W | F | V | S | . |
. |
Q | L | P | K | T | R | S | G | K | M | L | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   | . |   |
|   |   |
|   |   |
|   | . | . |   |
|
|   |
|   |   |
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |
| . |
|
|
|   |   |
|
Template Sequence |   |
D | L | S | T | D | N | . |
. |
. |
. |
. |
. |
. |
Y | I | E | L | E | K | I | R | R | D | I | I | R | Q | L | K | D | E | I | L | V | T | P | K | V | K | L | V | K | K | G | S | L | P | Q | S | . |
E | G | K | A | V | R |
Template Known Secondary structure |   |
S | S |
|
|
|
| . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
|  |  |  |  |  |
| T | T |
| S |
|
|
| . | S | S | S |
|
|
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
380 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | |
. | . | . | . | . | . |
  |