|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | D | V | I | C | I | G | A | A | I | V | D | I | P | L | Q | P | V | S | K | N | I | F | D | V | D | S | Y | P | L | E | R | I | A | M | T | T | G | G | D | A | I | N | E | A | T | I | I | S | R | L | G | H | R | T | A | L | M | S | R | I | G | K | D | A | A | G | Q | F | I | L | D | H | C | R | K | E | N | I | D |
Query Conservation |   |
  |   |
|
|   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
|
|   |
|
|   |   |
|   |   |
|   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   | . |
|   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |
|
|   |
| . |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |
Template Sequence |   |
M | I | Y | T | V | T | F | N | P | S | I | D | Y | V | I | F | . |
T | N | D | F | K | . |
I | D | G | L | N | R | A | T | A | T | Y | K | F | A | G | G | K | G | I | N | V | S | R | V | L | K | T | L | D | V | E | S | T | A | L | G | F | A | G | G | F | . |
P | G | K | F | I | I | D | T | L | N | N | S | A | I | Q |
Template Known Secondary structure |   |
|  |  |  |  |  | S | S |
|  |  |  |  |  |  |  | . |  | S | S |
|
| . | T | T | S |
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . |  |
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | |
. | . | . | 20 | . | |
. | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | |
. | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
  |
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | |
|
130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | Q | S | L | K | Q | D | V | S | I | D | T | S | I | N | V | G | L | V | T | E | D | G | E | R | T | F | V | T | N | R | N | G | S | L | W | K | L | N | I | D | D | V | D | F | A | . |
. |
R | F | S | Q | A | K | L | L | S | L | A | S | I | F | N | S | P | L | L | D | G | K | A | L | T | E | I | F | T | Q | A | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | N | F | I | E | V | D | E | D | T | R | I | N | V | K | L | . |
. |
. |
. |
K | T | G | Q | E | T | E | I | N | A | P | G | P | H | I | T | S | T | Q | F | E | Q | L | L | Q | Q | I | K | N | T | T | S | E | D | I | V | I | V | A | G | S | . |
V | P | S | S | I | P | S | D | A | Y | A | Q | I | A | Q | I | T | A |
Template Known Secondary structure |   |
 |
|
|  |  |  | S | S |
|
|  |  |  |  |  |  | . | . | . | . |
| S | S | S |
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T |
|  |  |  |  |  | S |
| . |
|
| T | T | S |
| T | T |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . | . | . |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | |
|
|
|
. | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | |
. | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
  |
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | R | Q | M | I | I | C | A | D | M | I | K | P | R | L | N | E | T | L | D | D | I | C | E | A | L | S | Y | V | D | Y | L | F | P | N | F | A | E | A | K | L | L | T | . |
. |
. |
. |
. |
G | K | E | T | L | D | E | I | A | D | C | F | L | A | C | G | V | K | T | V | V | I | K | T | G | K | D | G | C | F | I | K |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |   |   |   |
Template Sequence |   |
Q | T | G | A | K | L | V | V | D | A | E | . |
. |
. |
. |
. |
. |
K | E | L | A | E | S | V | L | P | Y | H | P | L | F | I | K | P | N | K | D | E | L | E | V | M | F | N | T | T | V | N | S | D | A | D | V | I | K | Y | G | R | L | L | V | D | K | G | A | Q | S | V | I | V | S | L | G | G | D | G | A | I | Y | I |
Template Known Secondary structure |   |
 |  |
|
|  |  |  |  |  | S |
| . | . | . | . | . | . |  |  |  |  |  |  |  | G | G | G |
|
| S | B | B |
|
| B |  |  |  |  |  |  |  |  | T | S |
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |
|  |  |  |  |
| G | G | G |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|  |  |  |
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . |
  |
  |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | G | D | M | T | M | K | V | P | A | V | A | G | I | T | A | I | D | T | I | G | A | G | D | N | F | A | S | G | F | I | A | A | L | L | E | G | K | N | L | R | E | C | A | R | F | A | N | A | T | A | A | I | S | V | L | S | V | G | A | T | T | G | V | K | N | R | K | L | V | E | Q | L | L | E | E | Y | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|   |
|   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   | . |   |   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |
| . | . | . | . |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
D | K | E | I | S | I | K | A | V | N | P | Q | . |
G | K | V | V | N | T | V | G | S | G | D | S | T | V | A | G | M | V | A | G | I | A | S | G | L | S | I | E | K | A | F | Q | Q | A | V | A | C | G | T | A | T | A | F | D | E | D | . |
. |
. |
. |
L | A | T | R | D | A | I | E | K | I | K | S | Q | V | T |
Template Known Secondary structure |   |
| S | S |  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S | . | . | . | . | S |
|
|  |  |  |  |  |  |  |  |  |  |
|  |
Template Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |
|
|
|
| . |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
227 | . | . | 230 | . | . | . | . | . | . | . | . | |
. | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
|
|
|
. | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
  |