Job Description P27253 Confidence 100.00% Date Thu Jan 5 11:43:33 GMT 2012 Rank 2 Aligned Residues 697 % Identity 58% Template c3bicA_ PDB info PDB header:isomerase Chain: A: PDB Molecule:methylmalonyl-coa mutase, mitochondrial precursor; PDBTitle: crystal structure of human methylmalonyl-coa mutase Resolution 2.60 Å

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		3	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	V	Q	E	W	Q	Q	L	A	N	K	E	L	S	R	R	E	K	T	V	D	S	L	V	H	Q	T	A	E	G	I	A	I	K	P	L	Y	T	E	A	D	L	D	N	L	E	V	T	G	T	L	P	G	L	P	P	Y	V	R	G	P	R	A	T	M	Y	T	A	Q	P	W	T	I	R	Q	Y	A	G	F	S
Query Conservation
Alig confidence															.							.																										.	.
Template Conservation															.							.																										.	.
Template Sequence		L	H	P	E	W	A	A	L	A	K	K	Q	L	.	K	G	K	N	P	E	.	D	L	I	W	H	T	P	E	G	I	S	I	K	P	L	Y	S	K	R	D	T	M	D	L	P	.	.	E	E	L	P	G	V	K	P	F	T	R	G	P	Y	P	T	M	Y	T	F	R	P	W	T	I	R	Q	Y	A	G	F	S
Template Known Secondary structure		S												T	.	T	T			G	G	.	G	G					T	T	S					S				G	G	G	G	T	T			.	.				T	T	S	T	T		T	T		S	S	S	S	T	T	T	T	S											S
Template Predicted Secondary structure															.							.																										.	.
Template SS confidence
		39	40	.	.	.	.	.	.	.	.	.	50	.		.	.	.	.	.	.		.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.			.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.
		83	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	A	K	E	S	N	A	F	Y	R	R	N	L	A	A	G	Q	K	G	L	S	V	A	F	D	L	A	T	H	R	G	Y	D	S	D	N	P	R	V	A	G	D	V	G	K	A	G	V	A	I	D	T	V	E	D	M	K	V	L	F	D	Q	I	P	L	D	K	M	S	V	S	M	T	M	N	G	A	V	L	P
Query Conservation
Alig confidence																						.	.
Template Conservation																						.	.
Template Sequence		T	V	E	E	S	N	K	F	Y	K	D	N	I	K	Q	Q	G	L	S	V	.	.	A	F	D	L	A	T	H	R	G	Y	D	S	D	N	P	R	V	R	G	D	V	G	M	A	G	V	A	I	D	T	V	E	D	T	K	I	L	F	D	G	I	P	L	E	K	M	S	V	S	M	T	M	N	G	A	V	I	P
Template Known Secondary structure		S																				.	.		B						T	T			T	T		G	G	G	T	T	T	T	T	S	S	S	B				S								T	T	T			T	T	T								S	T	T
Template Predicted Secondary structure																						.	.
Template SS confidence
		115	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.			.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.
		163	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	L	A	F	Y	I	V	A	A	E	E	Q	G	V	T	P	D	K	L	T	G	T	I	Q	N	D	I	L	K	E	Y	L	C	R	N	T	Y	I	Y	P	P	K	P	S	M	R	I	I	A	D	I	I	A	W	C	S	G	N	M	P	R	F	N	T	I	S	I	S	G	Y	H	M	G	E	A	G	A	N	C	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	L	A	N	F	I	V	T	G	E	E	Q	G	V	P	K	E	K	L	T	G	T	I	Q	N	D	I	L	K	E	F	M	V	R	N	T	Y	I	F	P	P	E	P	S	M	K	I	I	A	D	I	F	E	Y	T	A	K	H	M	P	K	F	N	S	I	S	I	S	G	Y	H	M	Q	E	A	G	A	D	A	I
Template Known Secondary structure												T	T	T			G	G	G															T	T					S																					T	T	S	B												T	T
Template Predicted Secondary structure
Template SS confidence
		195	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.
		243	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.		.	.	310	.	.	.	.	.	.	.	.	.	320	.
Predicted Secondary structure																																																																			.
Query SS confidence																																																																			.
Query Sequence		Q	Q	V	A	F	T	L	A	D	G	I	E	Y	I	K	A	A	I	S	A	G	L	K	I	D	D	F	A	P	R	L	S	F	F	F	G	I	G	M	D	L	F	M	N	V	A	M	L	R	A	A	R	Y	L	W	S	E	A	V	S	G	F	G	A	Q	.	D	P	K	S	L	A	L	R	T	H	C	Q	T	S
Query Conservation																																																																			.
Alig confidence																																																																			.
Template Conservation
Template Sequence		L	E	L	A	Y	T	L	A	D	G	L	E	Y	S	R	T	G	L	Q	A	G	L	T	I	D	E	F	A	P	R	L	S	F	F	W	G	I	G	M	N	F	Y	M	E	I	A	K	M	R	A	G	R	R	L	W	A	H	L	I	E	K	M	F	Q	P	K	N	S	K	S	L	L	L	R	A	H	C	Q	T	S
Template Known Secondary structure																					T	T							G	G	G									S																											S	S	G	G	G	G
Template Predicted Secondary structure
Template SS confidence
		275	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.
		322	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	W	S	L	T	E	Q	D	P	Y	N	N	V	I	R	T	T	I	E	A	L	A	A	T	L	G	G	T	Q	S	L	H	T	N	A	F	D	E	A	L	G	L	P	T	D	F	S	A	R	I	A	R	N	T	Q	I	I	I	Q	E	E	S	E	L	C	R	T	V	D	P	L	A	G	S	Y	Y	I	E	S	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	W	S	L	T	E	Q	D	P	Y	N	N	I	V	R	T	A	I	E	A	M	A	A	V	F	G	G	T	Q	S	L	H	T	N	S	F	D	E	A	L	G	L	P	T	V	K	S	A	R	I	A	R	N	T	Q	I	I	I	Q	E	E	S	G	I	P	K	V	A	D	P	W	G	G	S	Y	M	M	E	C	L
Template Known Secondary structure		S	T	T			S	S	S	T	T																T	T		S							T	T	T	T	T	S	S																			T	S		G	G	G	S	S	S	T	T	T	T
Template Predicted Secondary structure
Template SS confidence
		355	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.
		402	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	D	Q	I	V	K	Q	A	R	A	I	I	Q	Q	I	D	E	A	G	G	M	A	K	A	I	E	A	G	L	P	K	R	M	I	E	E	A	S	A	R	E	Q	S	L	I	D	Q	G	K	R	V	I	V	G	V	N	K	Y	K	L	D	H	E	D	E	T	D	V	L	E	I	D	N	V	M	V	R	N	E	Q
Query Conservation
Alig confidence																																																																		.	.
Template Conservation																																																																		.	.
Template Sequence		T	N	D	V	Y	D	A	A	L	K	L	I	N	E	I	E	E	M	G	G	M	A	K	A	V	A	E	G	I	P	K	L	R	I	E	E	C	A	A	R	R	Q	A	R	I	D	S	G	S	E	V	I	V	G	V	N	K	Y	Q	L	E	K	E	D	.	.	T	V	L	A	I	D	N	T	S	V	R	N	R	Q
Template Known Secondary structure																				T									T																				T	S	S			B	T	T	T	B	S			S	S			.	.
Template Predicted Secondary structure																																																																		.	.
Template SS confidence
		435	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.			.	500	.	.	.	.	.	.	.	.	.	510	.	.
		482	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.		.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Predicted Secondary structure																																	.
Query SS confidence																																	.
Query Sequence		I	A	S	L	E	R	I	R	A	T	R	D	D	A	A	V	T	A	A	L	N	A	L	T	H	A	A	Q	H	N	E	.	N	L	L	A	A	A	V	N	A	A	R	V	R	A	T	L	G	E	I	S	D	A	L	E	V	A	F	D	R	Y	L	V	P	S	Q	C	V	T	G	V	I	A	Q	S	Y	H	Q	S
Query Conservation																																	.
Alig confidence																																	.																																									.	.	.	.
Template Conservation																																																																										.	.	.	.
Template Sequence		I	E	K	L	K	K	I	K	S	S	R	D	Q	A	L	A	E	R	C	L	A	A	L	T	E	C	A	A	S	G	D	G	N	I	L	A	L	A	V	D	A	S	R	A	R	C	T	V	G	E	I	T	D	A	L	K	K	V	F	G	E	H	K	A	N	D	R	M	V	S	G	A	.	.	.	.	Y	R	Q	E
Template Known Secondary structure												S																					S												T	T																										S		.	.	.	.
Template Predicted Secondary structure																																																																										.	.	.	.
Template SS confidence
		515	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.					.	.	.	590
		561	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.		.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																						.
Query SS confidence																																						.
Query Sequence		E	K	S	A	S	E	F	D	A	I	V	A	Q	T	E	Q	F	L	A	D	N	G	R	R	P	R	I	L	I	A	K	M	G	Q	D	G	.	H	D	R	G	A	K	V	I	A	S	A	Y	S	D	L	G	F	D	V	D	L	S	P	M	F	S	T	P	E	E	I	A	R	L	A	V	E	N	D	V	H	V	V
Query Conservation																																						.
Alig confidence																																						.														.
Template Conservation																																																				.
Template Sequence		F	G	E	S	K	E	I	T	S	A	I	K	R	V	H	K	F	M	E	R	E	G	R	R	P	R	L	L	V	A	K	M	G	Q	D	G	H	D	R	G	A	K	V	I	A	T	G	F	A	D	.	L	G	F	D	V	D	I	G	P	L	F	Q	T	P	R	E	V	A	Q	Q	A	V	D	A	D	V	H	A	V
Template Known Secondary structure				S																			S	S									B	S	S																	.	T	T								T	T	B													T		S
Template Predicted Secondary structure																																																				.
Template SS confidence
		591	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640		.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.
		640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	A	S	S	L	A	A	G	H	K	T	L	I	P	E	L	V	E	A	L	K	K	W	G	R	E	D	I	C	V	V	A	G	G	V	I	P	P	Q	D	Y	A	F	L	Q	E	R	G	V	A	A	I	Y	G	P	G	T	P	M	L	D	S	V	R	D	V	L	N	L	I	S	Q	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	V	S	T	L	A	A	G	H	K	T	L	V	P	E	L	I	K	E	L	N	S	L	G	R	P	D	I	L	V	M	C	G	G	V	I	P	P	Q	D	Y	E	F	L	F	E	V	G	V	S	N	V	F	G	P	G	T	R	I	P	K	A	A	V	Q	V	L	D	D	I	E	K	C
Template Known Secondary structure							S	S																	T		T	T	S							S			G	G	G								T							T	T
Template Predicted Secondary structure
Template SS confidence
		670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.