|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 20 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
R | P | L | L | Q | L | A | L | D | H | S | S | L | E | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | Q | R | D | V | T | L | L |
Query Conservation |   |
|   |   |
|   |
|
|
|
|   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|
|
|
|
| . |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
Template Sequence |   |
N | T | C | L | C | I | G | L | D | . |
P | D | E | A | D | I | K | S | F | M | Q | S | E | K | Q | N | G | Y | Q | S | V | K | K | N | L | S | N | S | G | E | L | F | A | P | Q | M | G | G | Q | M | L | L | A | T | P | P | K | E | A | Q | E | K | D | E | F | F | Y | F | F | N | H | F | C | F | Y | I | I | N | E | T |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |  |  |  |  |  |  |  |  | S |
|
|
|
|
|
|
| S | S | S |  |  |  |  |  |
|
|
|
|
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
33 | . | . | . | . | . | . | 40 | . | |
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . |
  |
  |   |
26 | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | |
|
|
|
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | D | S | V | D | I | V | E | A | G | T | I | L | C | L | N | E | G | L | G | A | V | K | A | L | R | E | Q | C | P | . |
. |
. |
. |
. |
D | K | I | I | V | A | D | W | K | V | A | D | A | G | E | T | L | A | Q | Q | A | F | G | A | . |
. |
. |
. |
G | A | N | W | M | T | I | I | C | A | A | P | L | A | T | V | E |
Query Conservation |   |
  |   |   |
|
|   |
|
|
|
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
|
|
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|
|
|
|   |
|
|
|
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |   |
|
|   |
|   |
|   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|   |
|   |
|   |
Template Sequence |   |
K | E | Y | A | L | A | Y | K | M | N | F | A | F | Y | L | P | Y | G | S | L | G | V | D | V | L | K | N | V | F | D | Y | L | H | H | L | N | V | P | T | I | L | D | I | K | M | N | D | I | G | N | T | V | K | H | Y | R | K | F | I | F | D | Y | L | R | S | D | S | C | T | A | N | I | Y | M | G | T | Q | M | L | R |
Template Known Secondary structure |   |
G | G | G |
| S |  |  |  |  |  | G | G | G | G | S | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| S |  |  |  |  |
|
| T | T |
| S | T | T |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
126 | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . |
  |
  |   |
97 | . | . | |
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | |
|
|
150 | . | . |
Predicted Secondary structure |   |
 |  |  | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |  |  |  |
Query SS confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
Query Sequence |   |
K | G | H | . |
A | M | A | Q | R | C | G | G | E | I | Q | I | E | L | F | G | N | W | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | D | A | R | D | W | H | R | I | G | V | R | Q | A | I | Y | H | R | G | R | D | A | Q | A | S | G | Q | Q | W | G | . |
. |
. |
E | A | D |
Query Conservation |   |
  |   |   | . |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . |   |   |   |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |
|   |   |
|
|
|
|
|
|
|   |
|   |
|
Template Sequence |   |
D | I | C | L | D | E | E | C | K | R | Y | Y | S | T | F | V | L | V | K | T | T | N | A | D | S | H | I | F | Q | N | R | L | S | L | D | G | K | E | A | Y | V | V | I | A | E | E | V | Q | K | M | A | K | Q | L | H | L | . |
. |
. |
. |
. |
. |
E | E | N | G | E | F | V | G | F | V | V | G | A | N | C | Y | D | E |
Template Known Secondary structure |   |
 |  |  | B |
| T | T | S |
|
| B |
|  |  |  |  |  |  |  |
| S | S | T | T | T |  |  |  |  | T | T |
|  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | . | . | . | . | . | . | G | G | G | T |
|
|  |  |  |  |  |
| T | T |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
206 | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . |
  |
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | R | M | K | A | L | S | D | I | G | L | E | L | S | I | T | G | G | I | T | P | A | D | L | P | L | F | K | D | I | R | V | K | . |
. |
. |
. |
. |
. |
A | F | I | A | G | R | A | L | A | G | A | A | N | P | A | Q | V | A | G | D | F | H | A | Q | I | D | A | I | W | G |
Query Conservation |   |
  |   |   |
|
|   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
| . | . | . | . | . | . |   |
|
|
|
|
|
|
|   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |   |   |
|   |   |   |
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |
|
|   |
|   |
|
|   |   |
|
|   |   |   |   |
|   |
|   |
|   |
|
|
Template Sequence |   |
I | K | K | I | R | E | L | F | P | D | C | Y | I | L | A | P | G | V | G | A | Q | K | G | D | L | R | K | M | L | C | N | G | Y | S | K | N | Y | E | K | V | L | I | N | V | G | R | A | I | T | K | S | G | S | P | Q | Q | A | A | R | E | Y | H | Q | Q | I | K | E | V | L | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
| T | T |
|
|  |  |  |
|
| B | S | T | T |
| B |
|  |  |  |  |  |  |  |  |
|
| S | S | G | G | G |  |  |  |  |  |
|  |  |  |  | T | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
  |