|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
|
|
|
. | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
S | R | P | L | L | Q | L | A | L | D | H | S | S | L | E | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | Q | R | D | V | T | L | L | K | D | S | V | D | I | V | E | A | G | T | I | L | C | L | N | E | G | L | G | A | V | K | A | L | R | E | Q | . |
. |
. |
. |
. |
C | P | D | K | I |
Query Conservation |   |
  |
|   |   |
|   |
|
|
|
|   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |   | . | . | . | . | . |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|
|
|
|
|
| . |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
Template Sequence |   |
K | N | G | F | V | C | I | G | L | D | . |
S | S | I | D | Y | I | P | E | N | X | K | A | G | K | S | V | S | E | A | L | F | S | Y | N | K | E | I | I | D | Q | T | Y | D | V | C | A | I | Y | K | L | Q | I | A | Y | Y | E | S | Y | G | I | E | G | X | I | A | Y | R | D | T | L | S | Y | L | R | E | K | D | L | L |
Template Known Secondary structure |   |
 |  |
| S |  |  |  |  |
|
| . |
|
| G | G | G | S |
|  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
Template Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |
| . |
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
13 | . | . | . | . | . | . | 20 | . | . | |
. | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . |
  |
  |   |
59 | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | |
|
|
. | . | . | . | . | . | |
|
. | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  | . | . | . |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
I | V | A | D | W | K | V | A | D | A | G | E | T | L | . |
. |
. |
A | Q | Q | A | F | G | . |
. |
A | G | A | N | W | M | T | I | I | C | A | A | P | L | A | T | V | E | K | G | H | A | M | A | Q | R | C | G | G | E | I | Q | I | E | L | F | G | N | W | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|   |   |
|   |
|   |   |
|   |   |   |   |   | . | . | . |   |   |   |   |   |   | . | . |   |
|
|
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|
|
|   |
|   |   |
|
|
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |
|
|   |   |
|
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | I | G | D | V | K | R | S | D | I | A | A | S | A | K | X | Y | A | K | A | H | F | E | G | D | F | E | T | D | F | I | T | L | N | P | Y | X | G | X | D | S | I | E | P | Y | E | E | Y | I | E | K | G | D | K | G | V | F | V | L | L | R | T | S | N | P | G | A | K | D | F | E | V | L | P | V | D | G | E | E | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | S | G | G | G |
|
| S |  |  |  |  |
|
| T | T |
| G | G | G | T | G | G | G |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |
|
| S | G | G | G | G | T | T | T | T |
|  |  | T | T |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
92 | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . |
  |
  |   |
|
|
|
|
119 | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | |
|
|
. | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
|
|
|
. | . | . | . |
Predicted Secondary structure |   |
. | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |
Query SS confidence |   |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
L | D | D | A | R | D | W | H | R | I | G | V | R | Q | A | I | Y | H | R | G | R | D | A | Q | A | S | G | Q | Q | W | . |
. |
. |
G | E | A | D | L | A | R | M | K | A | L | S | D | I | G | L | E | L | S | I | T | G | G | I | T | P | A | D | L | P | L | F | K | D | I | . |
. |
. |
. |
R | V | K | A |
Query Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
|
|
|   |
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
Template Sequence |   |
F | Y | K | V | G | D | K | X | R | E | L | N | E | K | Y | I | G | . |
. |
. |
. |
. |
. |
K | S | G | F | G | P | I | G | L | V | V | G | A | T | H | S | E | E | V | E | K | I | R | K | R | Y | D | K | X | F | F | L | I | P | G | F | G | A | Q | K | A | D | S | X | N | V | Y | K | L | L | E | G | L | N | G | G | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
|
| . | . | . | . | . | . | T | T | S |
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |
|
|
|
| S | S |  |  |  |  |  |  |  |  | T | T |
| B | T | T | B | S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
172 | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . |
  |
  |   |
188 | . | 190 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | I | A | G | R | A | L | A | G | A | . |
. |
. |
. |
. |
A | N | P | A | Q | V | A | G | D | F | H | A | Q | I | D | A | I | W | G | G | A | R | A |
Query Conservation |   |
|
|
|
|
|
|
|   |   |
| . | . | . | . | . |   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
V | N | S | S | R | A | I | L | K | N | W | Q | N | Y | E | D | G | S | E | K | V | G | Y | Y | A | R | K | K | A | I | E | T | Y | E | E | I | K | A |
Template Known Secondary structure |   |
 |  |  |
|  |  |  |  | T | G | G | G | G | S | T | T | G | G | G |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . |
  |