Job Description P37678 Confidence 97.01% Date Thu Jan 5 11:56:52 GMT 2012 Rank 228 Aligned Residues 171 % Identity 13% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		12	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.		.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.			.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.
Predicted Secondary structure																		.																			.	.
Query SS confidence																		.																			.	.
Query Sequence		H	S	S	L	E	A	A	Q	R	D	V	T	L	L	K	D	.	S	V	D	I	V	E	A	G	T	I	L	C	L	N	E	G	L	G	.	.	A	V	K	A	L	R	E	Q	C	P	D	K	I	I	V	A	D	W	K	V	A	D	A	G	E	T	L	A	Q	Q	A	F	G	A	G	A	N	W	M	T	I	I	C
Query Conservation																		.																			.	.
Alig confidence																		.																			.	.																												.
Template Conservation																																																																		.
Template Sequence		I	V	S	T	P	V	K	I	K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	V	L	K	G	I	Q	K	F	P	G	I	N	Y	P	V	L	T	P	N	L	K	G	F	.	E	A	A	V	A	A	G	A	K	E	V	V	I	F	G
Template Known Secondary structure																		T	T		S										T	T	T		G	G	G	T	T								S				T	T		B							S					.						T	T		S
Template Predicted Secondary structure																																																																		.
Template SS confidence
		50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.		.	.	.	.	.	.	120	.	.	.	.	.	.	.	.
		89	90	.	.																.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.													.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.
Predicted Secondary structure						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		A	A	P	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	T	V	E	K	G	H	A	M	A	Q	R	C	G	G	E	I	Q	I	E	L	F	G	N	W	T	.	.	.	.	.	.	.	.	.	.	.	.	L	D	D	A	R	D	W	H	R	I	G	V	R	Q	A	I	Y	H	R	G	R	D	A
Query Conservation						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.	.	.	.	.																					.	.	.
Template Conservation																																																																															.	.	.
Template Sequence		A	A	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C	Y	E	I	S	L	G	D	T	.	.	.
Template Known Secondary structure			S									T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	S																T	T		S							T	.	.	.
Template Predicted Secondary structure																																																																															.	.	.
Template SS confidence
		129	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.
		142	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.			.	.	.	.	.	.	.					.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.
Predicted Secondary structure																						.	.								.	.	.	.
Query SS confidence																						.	.								.	.	.	.
Query Sequence		Q	A	S	G	Q	Q	W	G	E	A	D	L	A	R	M	K	A	L	S	D	.	.	I	G	L	E	L	S	I	.	.	.	.	T	G	G	I	T	P	A	D	L	P	L	F	K	D	I	R	V	K	A	F
Query Conservation																						.	.								.	.	.	.
Alig confidence		.	.																			.	.								.	.	.	.
Template Conservation		.	.
Template Sequence		.	.	I	G	V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V	S	V	V
Template Known Secondary structure		.	.	T																			S		G	G	G						B		T	T	S												T	T
Template Predicted Secondary structure		.	.
Template SS confidence
				206	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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