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Job DescriptionP0A9U1
Confidence100.00%DateThu Jan 5 11:11:22 GMT 2012
Rank6Aligned Residues464
% Identity28%Templatec2ygrD_
PDB info PDB header:hydrolaseChain: D: PDB Molecule:uvrabc system protein a; PDBTitle: mycobacterium tuberculosis uvra
Resolution3.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   12.......20.........30.........40.........50 .........60.....
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Query Sequence  EKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGAGKTTLM. . . . . . . . . . . . . . . . . . . . . RMLAGLLKPDSGSAT. . . . .
Query Conservation     
       
  


 
  

   


 








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Template Sequence  RLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPA
Template Known Secondary structure 
SSS

SSSS
STTSSTTTTTT
STTTS




SS


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   4.....10.........20.........30.........40.........50.........60.........70.........80...
 
   66...70......
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Query Sequence  . . VIGFDPIKNDG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ..
 
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Template Sequence  VSIDQKSTNRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVLAMPEGTRFLVLAPVVRTRKGEF
Template Known Secondary structure 
S





TT
BTTSSB
B
TTT

B
B


SS

SS


SSSSB
S
T
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   84.....90.........100.........110.........120.........130.........140.........150.........160...
 
  
Predicted Secondary structure  ................................................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation 




 
   
     
      
     
          
    
       
                          
Template Sequence  ADLFDKLNAQGYSRVRVDGVVHPLTDPPRARRQEKHDIEVVVDKRRLTDSVETALNLADGIVVLEFVDHRFSEKLACPNG
Template Known Secondary structure  TS

S
BSSS
B
TTS




TTS
B




SSS







TTBB
TT
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   164.....170.........180.........190.........200.........210.........220.........230.........240...
 
  
Predicted Secondary structure  ................................................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation              

 

  
 
  
 
 
     
    
     
   

                             
Template Sequence  HALAVDDLEPRSFSFNSPYGACPDCSGLGIRKEVDPELVVPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALGFDVD
Template Known Secondary structure 


S
S


GGGG
TTSTTTBBTTBSSS


SS

SSSSS
S
STT
SSTTS

SS
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   261........270.........280.........290.........300.........310.........320.........330.........340
 
   77..80......
Predicted Secondary structure  .........................................................


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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ALHAVLGYMP. . . . . . . . . . . . .
Query Conservation  .........................................................     

 
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Template Conservation   
       

 
                          
  
               
        
  
 
 

   
Template Sequence  TPPAKARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMSQTESEQMKERYEGFMRDVPCPVCAGTRLKPEI
Template Known Secondary structure 


T


S





SSS









S
TTTT
TTTTTS
B
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   341........350.........360.........370.........380.........390.........400.........410.........420
 
   87..90.........100.........110......... 120.........130. ........140.........150..
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Query Sequence  . . . . . QKFGLYEDLTVMENLNLYADLRSVTGEARKQTF. . . . . . . . ARLLEFTSLGPF. TGRLAGKLSGGMKQKLGLACT
Query Conservation  .....
   
   


 
 
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Template Conservation 
      
     
 
  
                
     

   
  
   

  
   
    




 


 

  
Template Sequence  LAVTLKSIAEVCELSIADCADFLNALTLGPREQAIAGQVLKEIRSRLGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQ
Template Known Secondary structure  T
B

GGG


TT

TTSTT
TTS
TTSBGGG

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   425....430.........440.........450.........460.........470.........480.........490.........500....
 
   153..... .160.........170.........180.........190.........200.........210 .........220....
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Query Sequence  LVGEPK. . VLLLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDEAEQCRDVLLM. . . . . . NEGELLYQGEPKAL
Query Conservation 
   
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Template Sequence  IGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWIVDIGPGAGEHGGRIVHSGPYDEL
Template Known Secondary structure  TT


S

TTTT


B

T
SSSSSGGG

S
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   515....520.........530.........540.........550.........560.........570.........580.........590....
 
   225....230.........240.........250.........260.........270.........280.........290.........300....
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Query Sequence  TQTMAGRSFLMTSPHEGNRKLLQRALKLPQVSDGMIQGKSVRLILKKEATPDDIRHADGMPEININETTPRFEDAFIDLL
Query Conservation                                                                                  
Alig confidence 

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Template Conservation    ..............................................................................
Template Sequence  LR. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ..............................................................................
Template Predicted Secondary structure  ..............................................................................
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   595.
 
   305....310.........320.........330.........340.........350.........360.........370... ......380..
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Query Sequence  GGAGTSESPLGAILHTVEGTPGETVIEAKELTKKFGDFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFK. . MMCGLLVPT
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Template Conservation           
                              
      
  
   



 







    
        
Template Sequence  NKDSITGAYLSGRESIEIPAIRRSVDPRRQLTVVGAREHNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRL
Template Known Secondary structure 
SS
TS





SS




TTS
STT

SSSSSTTSSTT
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   597..600.........610.........620.........630.........640.........650.........660.........670......
 
   383......390.........400.........410..
Predicted Secondary structure 




















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Query Sequence  SGQALVLGMDLKESSGKARQHLGYMAQKFS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation   
 
   
             
    
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Template Conservation   
                   
  
 
 
      
           

 

                
 
   
     
Template Sequence  NGARQVPGRHTRVTGLDYLDKLVRIDQSPIGRTPRSNPATYTGVFDKIRTLFAATNEAKVRGYKPGRFSFNVKGGRCEAC
Template Known Secondary structure  S






SS


GGG




S
S
SSTT
STTSTTT

GGGS
TTSTTTB
SSS
Template Predicted Secondary structure 




















































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   677..680.........690.........700.........710.........720.........730.........740.........750......
 
   413......420.... .....430.........440.........450. ...
Predicted Secondary structure  ...................................





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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LYGNLTVEQNLR. . FFSGVYGLRGRAQNEKISRMSEAFGLK. SIA
Query Conservation  ...................................
    

   
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Template Conservation   
 
        
           
       
        
   
     
                 
   

    
Template Sequence  TGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTVSEVLDMSIEEAAEFFEPIAGVHRYLRTLVDVGLGYVRL
Template Known Secondary structure  TTSS

SSS


TTTTS
SB
T

BTTB
TSBSTT
SS
SSSBT
Template Predicted Secondary structure 










































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   757..760.........770.........780.........790.........800.........810.........820.........830......
 
   455....460.........470........ .480.........490.........500.........510.........520.........530.
Predicted Secondary structure 






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Query Sequence  SHATDELPLGFKQRLALACSLMHE. . . PDILFLDEPTSGVDPLTRREFWLHINSMVEKGVTVMVTTHFMDEAEYCDRIGL
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Template Sequence  GQPAPTLSGGEAQRVKLASELQKRSTGRTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVIVIEHNLDVIKTSDWIID
Template Known Secondary structure  T

GGGS
SSS


SS
SSSTT

T




S
Template Predicted Secondary structure 




























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   837..840.........850.........860.........870.........880.........890.........900.........910......
 
   532 .......540.........550...
Predicted Secondary structure  ......








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Query Sequence  V. . . . . . YRGKLIASGTPDDLKAQSAND
Query Conservation 
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Template Conservation 

   
   
 

  

  

       
Template Sequence  LGPEGGAGGGTVVAQGTPEDVAAVPASY
Template Known Secondary structure  SSSTTS
S
S
TT
SS
Template Predicted Secondary structure 














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   917..920.........930.........940....
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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