|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | |
|
|
. | . | . | . | . | . | 30 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
|
|
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | I | D | L | G | G | T | K | T | E | V | I | A | L | G | D | A | G | E | Q | . |
. |
. |
L | Y | R | H | R | L | P | T | P | . |
. |
. |
. |
. |
. |
. |
. |
R | D | D | Y | R | Q | T | I | E | T | I | A | T | L | V | D | M | A | E | . |
. |
. |
Q | A | T | G | Q | R | G | T | V | G | M | G | I | P | G | S | I | S |
Query Conservation |   |
|
|
|   |
|
|
|   |   |   |   |   |
|   |
|   |   |
|   |
| . | . | . |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |
|   |
Template Sequence |   |
V | I | D | X | G | T | N | T | F | H | L | L | I | T | D | I | V | N | D | R | P | H | T | L | V | N | E | K | S | A | V | G | L | G | K | G | G | I | T | K | G | F | I | T | E | E | A | X | D | R | A | L | D | T | L | K | K | F | R | V | I | L | D | E | H | A | V | V | H | V | I | A | T | G | T | S | A | V | R | S |
Template Known Secondary structure |   |
 |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S | T | T | T | G | G | G | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
7 | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . |
  |
  |   |
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | Y | T | G | V | V | K | N | A | N | S | T | W | L | N | G | Q | P | F | D | K | D | L | S | A | R | L | Q | R | E | V | R | L | A | N | D | A | N | C | L | A | V | S | E | A | V | D | G | A | A | A | G | A | Q | T | V | F | A | V | I | I | G | T | G | C | G | A | G | V | A | F | N | G | R | A | H | I | G | G | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|
|
|
|   |
|
|
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | S | N | K | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | L | I | D | R | I | K | K | E | V | N | I | D | V | E | V | I | D | G | A | R | E | A | E | L | I | F | R | G | V | Q | Q | A | V | P | X | E | D | H | I | S | L | A | X | D | I | G | G | G | S | V | E | F | I | I | G | N | K | N | E | I | L | W |
Template Known Secondary structure |   |
| T | T |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
| T | T |
|
|  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |
| S | S |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
87 | . | . | 90 | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
  |
  |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | T | A | G | E | W | G | H | N | P | L | P | W | M | D | E | D | E | L | R | Y | R | E | E | V | P | C | Y | C | G | K | Q | G | C | I | E | T | F | I | S | G | T | G | F | A | M | D | Y | R | R | L | S | G | H | A | L | K | G | S | E | I | I | R | L | V | E | E | S | D | P | V | A | E | L | A | L | R | R | Y | E |
Query Conservation |   |
  |   |
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | Q | S | F | E | I | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Q | R | L | I | D | R | F | H | V | H | D | P | X | R | E | D | D | R | V | X | X | H |
Template Known Secondary structure |   |
 |  |  |  | S |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  | S |
|
|
| S | S |
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
155 | . | . | . | . | 160 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
  |
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
|
|
. | . | . | . | . | . | 250 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|  |  |  |  |  |
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | L | A | K | S | L | A | H | V | V | N | I | L | . |
. |
. |
D | P | D | V | I | V | L | G | G | G |
Query Conservation |   |
  |   |
|
|   |   |
|   |   |
|   |   |   |
| . | . | . |   |
|   |   |
|
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
Template Sequence |   |
N | Y | F | D | E | V | L | V | P | L | E | K | A | I | N | T | W | R | P | T | Q | L | I | G | C | S | G |
Template Known Secondary structure |   |
 |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  | S |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . |
  |