|   |
22 | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
|
|
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | D | R | Y | G | F | G | N | I | A | E | N | I | S | R | S | I | L | T | L | . |
. |
. |
P | L | E | A | S | N | V | V | G | I | E | G | A | W | G | S | G | K | T | S | L | L | N | L | I | L | R | N | L | A | L | K | K | D | A | H | T | H | V | L | H | I | S | P | W | L | S | G | G | S | P | V | E | A | L | F | L |
Query Conservation |   |
  |
|   |
|
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   | . | . | . |   |   |   |   |   |   |
|
|
|
|   |
|   |
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|   |
|
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
| . |
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
| . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |
Template Sequence |   |
D | E | F | I | G | Q | E | N | V | K | K | K | L | S | L | A | L | E | A | A | K | M | R | G | E | V | L | D | H | V | L | . |
L | A | G | P | P | G | L | G | K | T | T | L | A | H | I | I | A | S | E | L | . |
. |
. |
. |
. |
. |
Q | T | N | I | H | V | T | S | G | P | V | L | V | K | . |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
G | G |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|  |  | . |  |  | S | S | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | T |
|
|  |  |  |  |  | T | T | T |
|
| S | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  | . |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
25 | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 80 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
  |
  |   |
99 | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | V | A | T | V | I | Q | Q | E | M | E | I | R | Y | P | P | K | G | F | K | K | L | W | R | K | Y | L | L | S | P | E | A | Q | K | V | I | E | Y | A | Q | D | T | S | S | R | V | L | P | L | V | Q | Y | I | G | Q | F | S | S | I | I | N | W | I | A | G | G | I | K | V | F | S | D | S | R | L | A | V | D | Q | K |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
179 | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | T | T | K | L | R | A | E | I | A | G | Q | L | V | S | L | D | L | K | F | I | V | V | M | D | D | L | D | R | L | E | P | S | Q | V | A | E | V | F | R | L | V | R | A | V | A | D | L | P | R | F | T | H | I | L | C | Y | D | R | Q | I | I | T | H | A | V | E | H | A | L | N | I | E | D | G | S | R | Y | L | Q |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |
|   |
|
|
|
|
|
|
|
|   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
Q | G | D | M | A | A | I | L | T | S | L | E | R | G | D | V | L | F | I | D | E | I | H | R | L | N | K | A | V | E | E | L | L | Y | S | A | I | E | D | F | Q | I | D | I | Q | P | F | T | L | V | G | A | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | R | S | G | L | L | S | S | P | L | R |
Template Known Secondary structure |   |
. | . | . | . | . |  |  |  |  |  |  |  |  |  | T |
|
| T | T |
|  |  |  |  |  | T | G | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | S |
| G | G | G | S |
|  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 150 | . | . | . |
  |
  |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | I | I | Q | L | S | F | K | L | P | R | P | E | A | F | D | L | R | N | E | F | R | Q | R | A | E | A | L | Y | Q | Q | I | N | N | Q | P | P | D | S | G | M | V | R | D | L | I | A | V | T | D | T | Y | G | A | A | L | S | T | P | R | E | I | H | Q | A | I | N | S | L | I | F | L | Y | P | G | M | R | D | F | V |
Query Conservation |   |
|
|
|
|
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
| . | . | . | . | . | . |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | R | F | G | I | I | L | E | L | D | F | Y | T | V | K | E | L | K | E | I | I | K | R | A | A | S | L | . |
. |
. |
. |
. |
M | D | V | E | I | E | D | A | A | A | E | M | I | A | K | R | S | R | G | . |
. |
. |
. |
. |
. |
T | P | R | I | A | I | R | L | T | K | R | V | R | D | M | L | T | V | V | K | A | D | R |
Template Known Secondary structure |   |
T | T |
| S |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | T | T |
|
| B |
|  |  |  |  |  |  |  |  |  | T | S | T | T | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
169 | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
  |
  |   |
339 | 340 | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
Query Sequence |   |
Y | F | P | D | L | C |
Query Conservation |   |
  |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|
Template Sequence |   |
I | N | T | D | I | V |
Template Known Secondary structure |   |
B |
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
  |   |
238 | . | 240 | . | . | . |
  |