|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
R | I | L | H | T | S | D | W | H | L | G | Q | N | F | Y | S | K | S | R | E | A | E | H | Q | A | F | L | D | W | L | L | E | T | A | Q | T | H | Q | V | D | A | I | I | V | A | G | D | V | F | D | T | G | S | P | P | S | Y | A | R | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|   |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | V | L | A | I | K | N | F | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | R | F | D | L | L | P | K | L | K | G | V | I | A | E | K | Q | P | D | I | L | V | V | V | G | N | I | L | K | N | E | A | L | E | K | E | Y | E | R | A | H | L | A | R | R | E | P | N | R | K | V | I | H | E | N | E | H | Y | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |
|
| T | . | . | . | . | . | . | . | . | . | . | . | . | T |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
7 | . | . | 10 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . |
  |
  |   |
|
|
|
63 | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
Y | N | R | F | V | V | N | L | Q | Q | T | G | C | H | L | V | V | L | A | G | N | H | D | S | V | A | T | L | N | E | S | R | D | I | M | A | F | L | N | T | T | V | V | A | S | A | G | H | A | P | Q | I | L | P | R | R | D | G | T | P | G | A | V | L | C | P | I | P | F | L | R | P | R | D | I | I | T |
Query Conservation |   |
. | . | . |   |   |   |   |
|   |   |
|   |   |   |   |
|
|
|   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | E | T | L | D | K | F | F | R | E | I | G | E | L | G | V | K | T | F | V | V | P | G | K | N | D | A | P | L | K | I | F | L | R | A | A | Y | E | A | E | T | A | Y | P | N | I | R | V | L | H | E | G | F | A | G | W | R | G | E | F | E | V | I | G | F | G | G | L | L | T | E | H | E | F | E | E | D | F | V | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
|
| T | T | S |
|
|  |  |  |  |  |  |  |  |  |  | T | T | T | T |
| T | T |  |  |  |
| S | S |  |  |  |  |  | T | T | T |  |  |  |  |  |  |
| S |  |  |  | S | S |
|
| B | S | S | S | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
75 | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
  |
  |   |
140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | |
. | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
| . |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Query Sequence |   |
S | Q | A | G | L | N | G | I | E | K | Q | Q | H | L | L | A | A | I | T | D | Y | Y | Q | Q | H | Y | A | D | A | C | K | L | R | G | D | Q | P | L | P | I | I | A | T | G | H | L | T | T | V | G | A | S | K | S | D | A | V | R | D | I | Y | I | G | T | L | D | A | F | P | A | Q | N | F | P | . |
P | A | D | Y | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |
|
|
|
Alig confidence |   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
Template Sequence |   |
K | Y | P | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | Y | V | E | Y | I | L | K | F | V | N | E | L | K | P | R | R | L | V | T | I | F | Y | T | P | P | I | G | E | F | V | D | R | T | P | E | D | P | K | H | H | G | S | A | V | V | N | T | I | I | K | S | L | N | P | E | V | A |
Template Known Secondary structure |   |
 |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  | G | G | G | G | G | G | S |
|
|
|  |  |  |  |  |  | S | S |
|
| S |
| S | S | T | T |
| B | T | T | B | S |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
155 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
  |
  |   |
219 | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | G | H | I | H | R | A | Q | I | I | G | G | M | E | H | V | R | Y | C | G | S | P | I | P | L | S | F | D | E | C | G | K | S | K | Y | V | H | L | V | T | F | S | N | G | K | L | E | S | V | E | N | L | N |
Query Conservation |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |
|   |
|   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|
|   |   |   | . | . | . | . | . | . | . | . | . |   |   |
|
|   |   |
|   |   |   |   |   | . |
|   |   |   |   |   |   |
Template Sequence |   |
I | V | G | H | V | G | K | G | H | E | L | V | G | N | T | I | V | V | N | P | G | E | F | E | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | R | Y | A | F | L | D | L | T | Q | H | K | . |
I | K | L | E | Q | F | S |
Template Known Secondary structure |   |
 |  |
| S | S |
|
|  |  |  |  |  | T | T |  |  |  |  |  |
|
| B | G | G | G | . | . | . | . | . | . | . | . | . | T |  |  |  |  |  |  | T | T | T | T |  | . |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|  | . |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
217 | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 250 | . | . | . | |
. | . | . | . | . | . | 260 |
  |