|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | I | L | H | T | S | D | W | H | L | G | Q | N | F | Y | S | K | S | R | E | A | E | H | Q | A | F | L | D | W | L | L | E | T | A | Q | T | H | Q | V | D | A | I | I | V | A | G | D | V | F | D | T | G | S | P | . |
. |
. |
P | S | Y | A | R | T | L | Y | N | R | F | V | V | N | L | Q | Q | T | G | C | H | L | V |
Query Conservation |   |
|
|
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . |   |
|   |   |
Template Sequence |   |
T | F | G | L | I | G | D | L | G | Q | S | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | S | N | T | T | L | S | H | Y | E | L | S | P | K | K | G | Q | T | V | L | F | V | G | D | L | S | Y | A | D | R | Y | P | N | H | D | N | V | R | W | D | T | W | G | R | F | T | E | R | S | V | A | Y | . |
Q | P | W | I |
Template Known Secondary structure |   |
 |  |  |  |  |
| S |
|
| S | B |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|
|
| S |  |  |  |
| S |
|
|
|
| G | G | G | S | G | G | G |
| T |  |  |  |  |  |  |  |  |  | T |  |  |  |  | T | T | . | S |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
129 | 130 | . | . | . | . | . | . | . | . | . | 140 | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | |
. | . | . | . |
  |
  |   |
79 | 80 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | A | G | N | H | D | . |
. |
. |
. |
. |
S | V | A | T | L | N | E | S | R | D | I | M | A | F | L | N | T | T | V | V | A | S | A | G | H | A | P | Q | I | L | P | R | R | D | G | T | P | G | A | V | L | C | P | I | P | F | L | R | P | R | D | I | I | T | S | Q | A | G | L | N | G | I | E | K | Q | Q | H | L |
Query Conservation |   |
  |
|   |
|
|
|
| . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |
|   |
|
|   |
|
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
W | T | A | G | N | H | E | I | E | F | A | P | E | I | N | E | T | E | P | F | K | P | F | S | Y | R | Y | H | V | P | Y | E | A | S | Q | S | T | S | P | F | W | Y | S | I | K | R | A | S | A | H | I | I | V | L | S | S | Y | S | A | Y | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |
|
|
| G | G | G | T |
|
| B | G | G | G | T | B |
| S | T | T |  |  |  |  |  |  |
|
|
|
| T | T | T | T | T |
| S | S | T | T | S |  |  |  |  |  | T | T |  |  |  |  |  |
|
| T | T | S |
|
| S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
197 | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | |
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
L | A | A | I | T | D | Y | Y | Q | Q | H | Y | A | D | A | C | K | L | R | G | D | Q | P | L | P | I | I | A | T | G | H | L | T | T | V | G | A | S | K | S | D | A | V | R | D | I | Y | I | G | T | L | D | A | F | P | A | Q | N | F | P | P | A | D | Y | I | A | L | G | H | I | H | R | A | Q | I | I | . |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|   |   |   |   |   | . | . | . | . |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
. | . |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   | . |   |
|   |   |   |
|   |
|
|
|
|
|   |
|
|   |
|   |
|   |
|
|   |
|   |   |
Template Sequence |   |
. |
. |
R | G | T | P | Q | Y | T | W | L | K | K | E | L | R | K | V | K | R | S | E | T | P | W | L | I | V | L | M | H | S | P | L | Y | N | S | Y | N | H | H | F | M | E | G | E | A | M | R | T | K | F | E | . |
A | W | F | V | K | Y | K | V | D | V | V | F | A | G | H | V | H | A | Y | E | R | S | E | R | V | S |
Template Known Secondary structure |   |
. | . | T | T | S |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | T |
|
|  |  |  |  |  |
| S | S |
| S | S |
|
| B | S | T | T | T | T | T | T |  |  |  |  |  |  |  |  | . |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S | S | S | S |  |  |  |  |
| S |  |  |
Template Predicted Secondary structure |   |
. | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
258 | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | |
. | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
G | G | M | E | H | V | R | Y | C | G | S | P | I | P | L | S | F | D | E | C | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | S | K | Y | V | H | L | V | T | F | S | N | G | K | L | E | S | V | E | N | L |
Query Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
N | I | A | Y | K | I | T | D | G | L | C | T | P | V | K | D | Q | S | A | P | V | Y | I | T | I | G | D | A | G | N | Y | G | V | I | D | S | N | M | I | Q | P | Q | P | E | Y | S | A | F | R | E | A | S | F | G | H | G | M | F | D | I | K | N | R | T | H | A | H | F | S | W | N |
Template Known Secondary structure |   |
|
|
|
|
| S | S | S |
|
|
| S |
|  |  |
| T | T | S |
|  |  |  |  |  |
|
| S |
| T | T | T |
|
|
|
|
| B |
| S | S |
|
| T | T |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
| S | S | S |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . |
  |