|   |
109 | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | |
. | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | I | K | P | E | H | F | K | N | W | V | E | W | A | K | A | N | Q | L | G | L | D | . |
F | N | P | S | C | F | S | H | P | L | S | A | D | G | F | T | L | S | H | A | D | D | S | I | R | Q | F | W | I | D | H | C | K | A | S | R | R | V | S | A | Y | F | G | E | Q | L | G | T | P | S | V | M | N | I | W | I | P |
Query Conservation |   |
  |
|   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|
| . |   |
|
|
|   |
|
|   |
|   |
|   |   |
|   |
|
|
|
|
|
|   |   |
|
|   |   |   |
|   |
|   |
|   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |
|   |
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . |
|   |   |
|
|   |   |   |
|   |   |   |   |   | . |
Template Sequence |   |
N | S | T | D | E | Q | I | R | A | F | H | D | K | C | A | A | H | K | V | T | G | Y | A | V | G | P | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | X | K | S | E | E | E | I | D | R | A | F | D | Y | . |
. |
. |
. |
A | K | R | V | G | V | K | L | I | V | G | V | P | N | . |
Template Known Secondary structure |   |
T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
| S |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |  | T |
| S |  |  |  |  |  |  |
| . |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |  |
|
|
|  |  |  |  |
|
|
| . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
|
|
|
. | . | . | . | . | . | 130 | . | . | . | . | . | . | . | |
  |
  |   |
188 | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | G | M | K | D | I | T | V | D | R | L | A | P | R | Q | R | L | L | A | A | L | D | E | V | I | S | E | K | L | N | P | A | H | H | I | D | A | V | E | S | K | L | F | G | I | G | A | E | S | Y | T | V | G | S | N | E | F | Y | M | G | Y | A | T | S | R | Q | T | A | L | C | L | D | A | G | H | F | H | P | T | E |
Query Conservation |   |
|
|
|
|   |   |   |   |
|   |
|   |   |
|   |
|
|   |
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|   |
|   |   |
|   |
|
|
|   |
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |
|   |
|
|
|
|   |
|
|   |
|
|   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |
|   |   |   |   | . |   |   |
|   |   |   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | E | L | L | P | Y | V | D | . |
K | K | V | K | E | Y | D | F | H | Y | A | I | H | L | H | G | P | D | I | K | T | . |
. |
Y | P | D | A | T | D | V | W | V | H | T | K | D | L | D | P | R | I | G | X | C | L | D | V | G | H | D | L | R | N | G |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | G | G | G |  |  |  |  |  | . |  |  |  |  |  |  | T |
|  |  |  |  |  |
|
|
| T | T |
| S | S | . | . | S |
| S |  |  |  |  |  |  |  |  | T | T | S |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  | . |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
138 | . | 140 | . | . | . | . | . | |
. | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
|
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . |
  |
  |   |
268 | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | |
. | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | |
|
. | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | I | S | D | K | I | S | A | A | M | L | Y | V | P | Q | L | . |
L | L | H | V | S | R | P | V | R | W | D | S | D | H | V | V | L | L | D | D | E | T | Q | A | I | A | S | E | I | V | R | H | . |
. |
D | L | F | D | R | V | H | I | G | L | D | F | F | D | A | S | I | N | R | I | A | A | W | V | I | G | T | R | N |
Query Conservation |   |
  |   |   |
|
|
|
|
|   |
|
|   |   |   |   |
| . |   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|   |   |   |
|
|   |   |
|   |   |
|
|
|   |   | . | . |   |   |   |   |
|
|   |   |   |
|
|   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   | . | . |   |   |
|   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |
|
|   |   |
|   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
Template Sequence |   |
C | D | P | V | A | D | L | K | K | Y | H | . |
. |
T | R | V | F | D | X | H | I | K | D | V | T | D | S | S | K | A | G | V | G | I | E | I | G | R | G | K | I | D | F | P | A | L | I | R | X | X | R | E | V | N | Y | T | G | X | C | S | L | E | Y | E | K | D | X | K | D | P | F | L | G | I | A | E | S | I | G | Y |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  | G | . | . | G | G |  |  |  |  |  |  |
|  |  | S |
| S | S | T | T |
|
|  |  |
| T | T | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |
|
|
| S | S | T | T | S |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
198 | . | 200 | . | . | . | . | . | . | . | . | |
|
. | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . |
  |
  |   |
345 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
Query Sequence |   |
M | K | K | A | L |
Query Conservation |   |
  |
|
|
|   |
Alig confidence |   |
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |
Template Sequence |   |
F | K | A | V | S |
Template Known Secondary structure |   |
 |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
  |   |
276 | . | . | . | 280 |
  |