|   |
133 | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | |
. | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | A | Q | L | L | C | R | I | T | G | A | E | D | A | C | I | V | N | N | N | A | A | A | V | L | L | M | L | A | A | T | A | . |
S | G | K | E | V | V | V | S | R | G | E | L | V | E | I | G | G | A | F | R | I | P | D | V | M | R | Q | A | G | C | T | L | H | E | V | G | T | T | N | R | T | H | A | N | D | Y |
Query Conservation |   |
  |   |   |   |   |
|
|   |
|   |
|   |
|   |
|   |
|   |   |
|
|   |   |
|   |   |
|
|
|   |
|
|   | . |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
Template Conservation |   |
  |
|
|   |   |
|
|   |
|   |
|   |   |   |   |
|   |   |   |
|
|
|   |
|
|   |   |   |
|   |
|
|   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |
Template Sequence |   |
A | L | E | G | K | I | A | K | L | E | H | A | E | A | C | A | A | T | A | S | G | M | G | A | I | A | A | S | V | W | T | F | L | K | A | G | D | H | L | I | S | D | D | C | L | Y | G | C | T | H | A | L | . |
. |
F | E | H | Q | L | R | K | F | G | V | E | V | D | F | I | D | M | A | V | . |
. |
. |
P | G | N | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  | S |
|
|
|  |  |  |  |  |  | . | . |  |  | T |  |  |  |  | T | T |
|  |  |  |  |  |
| T | T | S | . | . | . | T | T |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
| . | . | . |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
66 | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | |
|
. | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
|
|
. | . | . | 140 |
  |
  |   |
212 | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | Q | A | V | N | E | N | T | A | L | L | M | K | V | H | T | S | N | Y | S | I | Q | G | F | T | K | A | I | D | E | A | E | L | V | A | L | G | K | E | L | D | V | P | V | V | T | D | L | G | S | G | S | L | V | D | L | S | Q | Y | G | L | P | K | E | P | M | P | Q | E | L | I | A | A | G | V | S | L | V | S | F |
Query Conservation |   |
  |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | K | H | L | K | P | N | T | R | I | V | Y | F | E | T | P | A | N | P | T | L | K | . |
. |
. |
V | I | D | I | E | D | A | V | K | Q | A | R | K | Q | K | D | I | L | V | I | V | D | N | T | F | A | S | P | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | T | N | P | L | D | L | G | V | D | I | V | V | H |
Template Known Secondary structure |   |
 |  | T |
|
| T | T |  |  |  |  |  |  |  | S | S |
| T | T | T |
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  | T | T | S | S | S |
|  |  |  |  |  |
| T | T | T |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
| G | G | G | G | T |
| S |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | |
|
|
. | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 200 | . | . | . | . | . |
  |
  |   |
292 | . | . | . | . | . | . | . | 300 | . | |
|
|
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | G | D | K | L | L | G | G | P | Q | . |
. |
. |
A | G | I | I | V | G | K | K | E | M | I | A | R | L | Q | S | H | P | L | K | R | A | L | R | A | D | K | M | T | L | A | A | L | E | A | T | L | R | L | Y | L | H | P | E | A | L | S | E | K | L | P | T | L | R | L | L | T | R | S | A | E | V | I | Q | I | Q | A |
Query Conservation |   |
|   |   |
|   |   |
|
|   |   | . | . | . |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | A | T | K | Y | I | N | G | H | T | D | V | V | A | G | L | V | C | S | R | A | D | I | I | A | K | V | K | S | Q | G | I | K | D | I | T | G | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | I | S | P | H | D | A | W | L | I | T | R | G | T | L | T | L | D | M | R | V | K | R | A | A | E | N | A |
Template Known Secondary structure |   |
 | T | T | T | T | T | S | S | S | S | S |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
206 | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . |
  |
  |   |
369 | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
Q | R | L | Q | A | P | L | A | A | H | Y | G | A | E | F | A | V | Q | V | M | P | C | L | S | Q | I | G | S | G | S | L | P | V | D | R | L | P | S | A | A | L | T | F | T | P | H | D | G | R | G | S | H | L | E | S | L | A | A | R | W | R | E | L | P | V | P | V | I | G | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|   |   |
| . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | K | V | A | E | F | L | H | E | H | K | A | V | K | K | . |
. |
V | Y | Y | P | G | L | P | D | H | P | G | H | E | I | A | K | K | Q | M | K | M | F | G | S | M | I | A | F | D | V | D | G | L | E | K | A | K | K | V | L | D | N | C | H | V | V | S | L | A | V | S | L | G | G | P | E | S | L | I | Q | H | P | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
| T | T |
|
|
| . | . |  |  |
| T | T | S | T | T | S | T | T |  |  |  |  |  |  |  |
| S | S |
|
| S |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  | T |
| S | S | S |  |  |
| S | S |
|
| S | S | S |
|  |  |  |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
272 | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | |
|
. | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
439 | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | Y | D | G | R | L | W | L | D | L | R | C | L | E | D | E | Q | R | F | L | E | M | L | L | K |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |
|   |
|   |   |
|
|
|   |
|   |
|   |
|
|   |   |
|
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|   | . |
|   |
|   |   |
|
|   |
|   |   |
|   |   |
Template Sequence |   |
S | M | T | H | A | G | V | P | K | E | E | R | E | A | A | G | L | T | D | N | L | I | R | L | S | V | . |
G | C | E | N | V | Q | D | I | I | D | D | L | K | Q |
Template Known Secondary structure |   |
 |  | T | S | T | T | S |
|  |  |  |  |  |  | T | T |
|
| T | T |  |  |  |  |  |
| . |
| S | S |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  | . |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
351 | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | |
. | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 |
  |