|   |
129 | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | |
. | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | R | D | R | A | L | A | Q | L | L | C | R | I | T | G | A | E | D | A | C | I | V | N | N | N | A | A | A | V | L | L | M | L | A | A | T | A | . |
S | G | K | E | V | V | V | S | R | G | E | L | V | E | I | G | G | A | F | R | I | P | D | V | M | R | Q | A | G | C | T | L | H | E | V | G | T | T | N | R | T | H |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |
|   |
|   |
|   |   |
|
|   |   |
|   |   |
|
|
|   |
|
|   | . |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
Template Conservation |   |
|   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |
|
|   |   |
|
|   |   |   |
|   |
|
|   |   |   |
|
|   |
|
|   |   |   |   |   |
|   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |
|
Template Sequence |   |
P | T | L | N | L | L | E | A | R | M | A | S | L | E | G | G | E | A | G | L | A | L | A | S | G | M | G | A | I | T | S | T | L | W | T | L | L | R | P | G | D | E | V | L | L | G | N | T | L | Y | G | C | T | F | A | F | . |
. |
L | H | H | G | I | G | E | F | G | V | K | L | R | H | V | D | M | A | . |
. |
. |
D |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  | S | S |
|
| S |  |  |  |  |  | . | . |  |  |  | T | G | G | G | G | T |
|  |  |  |  |  |
| T | T | . | . | . |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
| . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
65 | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | |
|
. | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
|
. |
  |
  |   |
208 | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | N | D | Y | R | Q | A | V | N | E | N | T | A | L | L | M | K | V | H | T | S | N | Y | S | I | Q | G | F | T | K | A | I | D | E | A | E | L | V | A | L | G | K | E | L | D | V | P | V | V | T | D | L | G | S | G | S | L | V | D | L | S | Q | Y | G | L | P | K | E | P | M | P | Q | E | L | I | A | A | G | V | S |
Query Conservation |   |
  |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
| . | . | . | . |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|
|
|
|   |
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
L | Q | A | L | E | A | A | M | T | P | A | T | R | V | I | Y | F | E | S | P | A | N | P | N | M | . |
. |
. |
. |
H | M | A | D | I | A | G | V | A | K | I | A | R | K | H | G | A | T | V | V | V | D | N | T | Y | C | T | P | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | Q | R | P | L | E | L | G | A | D |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
|
| T | T |  |  |  |  |  |  |  | S | S |
| T | T | T |
| . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  | G | G | G | T |
|  |  |  |  |  |
| T | T | T |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
| G | G | G | G | T |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | |
|
|
|
. | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 200 | . | . | . |
  |
  |   |
288 | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|  | . | . |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | V | S | F | S | G | D | K | L | L | G | G | P | Q | . |
. |
A | G | I | I | V | G | K | K | E | M | I | A | R | L | Q | S | H | P | L | K | R | A | L | R | A | D | K | M | T | L | A | A | L | E | A | T | L | R | L | Y | L | H | P | E | A | L | S | E | K | L | P | T | L | R | L | L | T | R | S | A | E | V | I | Q |
Query Conservation |   |
|
|   |   |
|   |   |
|   |   |
|
|   |   | . | . |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |
|   |   |
|   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
L | V | V | H | S | A | T | Y | L | S | G | H | G | D | I | T | A | G | I | V | V | G | S | Q | A | L | V | D | R | I | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | Q | G | L | K | D | M | T | G | A | V | L | S | P | H | D | A | A | L | L | M | R | G | I | K | T | L | N | L | R | M | D | R | H | C |
Template Known Secondary structure |   |
 |  |  |  |  |
|
|
|
| S |
| S | S | S |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  | T |  |  |  |  |  | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
204 | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . |
  |
  |   |
366 | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
I | Q | A | Q | R | L | Q | A | P | L | A | A | H | Y | G | A | E | F | A | V | Q | V | M | P | C | L | S | Q | I | G | S | G | S | L | P | V | D | R | L | P | S | A | A | L | T | F | T | P | H | D | G | R | G | S | H | L | E | S | L | A | A | R | W | R | E | L | P | V | P | V | I | G | R | . |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|   |   |
| . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |
Template Sequence |   |
A | N | A | Q | V | L | A | E | F | L | A | R | Q | P | Q | V | E | L | I | H | Y | P | Q | P | G | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | I | A | F | E | L | K | G | G | I | G | A | G | R | R | F | M | N | A | L | Q | L | F | S | R | A | V | S | L | G | D | A | E | S | L | A | Q |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T |
| T | T |  |  |  |  |  |  |
|
|
| T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S |  |  |
| S |
|
| S |
| S | S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
271 | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
439 | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | Y | D | G | R | L | W | L | D | L | R | C | L | E | D | E | Q | R | F | L | E | M | L | L | K |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |
|   |
|   |   |
|
|
|   |
|   |
|   |
|
|   |   |
|
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|
|
|
| . |
|   |
|   |   |
|
|
|
|   |   |
|   |   |
Template Sequence |   |
H | P | A | S | M | T | H | S | S | Y | T | P | E | E | R | A | H | Y | G | I | S | E | G | L | V | R | L | S | V | . |
G | L | E | D | I | D | D | L | L | A | D | V | Q | Q |
Template Known Secondary structure |   |
| G | G | G | T | T | T | S | S | S |
|  |  |  |  |  |  | T | T |
|
| T | T |  |  |  |  |  |
| . |
| S | S |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  | . |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | |
. | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . |
  |