Job Description P0A821 Confidence 99.92% Date Thu Jan 5 11:06:39 GMT 2012 Rank 59 Aligned Residues 386 % Identity 15% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

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		19	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	R	D	S	S	F	L	S	L	R	D	T	Y	G	H	T	R	V	V	E	L	L	R	Q	M	L	D	E	A	R	E	V	I	R	G	S	Q	T	L	P	A	W	C	E	N	W	A	Q	E	V	D	A	R	L	T	K	E	A	Q	S	A	L	R	P	V	I	N	L	T	G	T	V	L	H	T	N	L	G	R	A
Query Conservation
Alig confidence																																															.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																															.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	P	A	D	T	V	Q	R	I	A	A	E	L	K	C	H	P	T	D	E	R	V	A	L	H	L	D	E	E	D	K	L	R	H	F	R	E	F	Y	I	P	K	I	Q	D	.	.	.	.	.	.	.	.	.	.	.	L	P	P	V	D	L	S	L	V	N	K	D	E	N	A	I	Y	F	L	G	N	S	L	G
Template Known Secondary structure															T	S		T	T	S										T		T	T	G	G	G	G			B			B	G	G	G	.	.	.	.	.	.	.	.	.	.	.	S	T	T			G	G	G	S		T	T		B					B	T	T	T	S
Template Predicted Secondary structure																																															.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		8	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.												.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.
		99	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.		120	.	.	.	.	.	.	.	.			.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.			.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.					.	.	.	.	.
Predicted Secondary structure																							.										.	.																	.	.																					.	.	.	.
Query SS confidence																							.										.	.																	.	.																					.	.	.	.
Query Sequence		L	Q	A	E	A	A	V	E	A	V	A	Q	A	M	R	S	P	V	T	L	E	.	Y	D	L	D	D	A	G	R	G	.	.	H	R	D	R	A	L	A	Q	L	L	C	R	I	T	G	A	.	.	E	D	A	C	I	V	N	N	N	A	A	A	V	L	L	M	L	A	A	T	.	.	.	.	A	S	G	K	E
Query Conservation																							.										.	.																	.	.																					.	.	.	.
Alig confidence																							.										.	.																	.	.																					.	.	.	.
Template Conservation
Template Sequence		L	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	A	N	E	K	E	I	A	L	M	N	A	L	T	V	N	L	H	L	L	M	L	S	F	F	K	P	T	P	K	R	Y	K
Template Known Secondary structure			B		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T	T					G	G	G					T			G	G	G					S																		S	S	S
Template Predicted Secondary structure
Template SS confidence
		78	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.
		170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.								.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.				.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																													.	.	.	.	.	.	.																				.	.	.
Query SS confidence																													.	.	.	.	.	.	.																				.	.	.
Query Sequence		V	V	V	S	R	G	E	L	V	E	I	G	G	A	F	R	I	P	D	V	M	R	Q	A	G	C	T	.	.	.	.	.	.	.	L	H	E	V	G	T	T	N	R	T	H	A	N	D	Y	R	Q	A	V	.	.	.	N	E	N	T	A	L	L	M	K	V	H	T	S	N	Y	S	I	Q	G	F	T	K	A	I
Query Conservation																													.	.	.	.	.	.	.																				.	.	.
Alig confidence																.	.												.	.	.	.	.	.	.																				.	.	.																					.	.	.	.
Template Conservation																.	.																																																													.	.	.	.
Template Sequence		I	L	L	E	A	K	A	F	P	S	D	H	Y	A	.	.	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P	R	E	G	E	E	T	L	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S	I	A	V	I	L	F	S	G	V	H	F	Y	T	G	Q	H	F	.	.	.	.
Template Known Secondary structure						T	T									.	.								T	T														T	T		S	S														G	G	G								S	B		T	T	T		B	B		.	.	.	.
Template Predicted Secondary structure																.	.																																																													.	.	.	.
Template SS confidence
		158	.	160	.	.	.	.	.	.	.	.	.	170	.			.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.
		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.			.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.
Predicted Secondary structure																																																												.	.
Query SS confidence																																																												.	.
Query Sequence		D	E	A	E	L	V	A	L	G	K	E	L	D	V	P	V	V	T	D	L	G	S	G	S	L	V	D	L	S	Q	Y	G	L	P	K	E	P	M	P	Q	E	L	I	A	A	G	V	S	L	V	S	F	S	G	D	K	L	L	.	.	G	G	P	Q	A	G	I	I	V	G	K	K	E	M	I	A	R	L	Q	S
Query Conservation																																																												.	.
Alig confidence																												.	.	.	.	.	.	.	.	.	.	.																						.	.
Template Conservation																												.	.	.	.	.	.	.	.	.	.	.
Template Sequence		N	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	V	G	N	.	.	.	.	.	.	.	.	.	.	.	V	E	L	Y	L	H	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G	A	G	G	I	A	G	A	F	I	H	E	K	H	A	H	T	I	K	P
Template Known Secondary structure													T	T								T	T	T	T	T	T	.	.	.	.	.	.	.	.	.	.	.	S								T								S	S	S	T	T				T	T									G	G	G	T	T	T	S
Template Predicted Secondary structure																												.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		232	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.												.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
		318	.	320	.	.																										.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.
Predicted Secondary structure							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		H	P	L	K	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	L	R	A	D	K	M	T	L	A	A	L	E	A	T	L	R	L	Y	L	H	P	E	A	L	S	E	K	L	P	T	L	R	L	L	T	R	S	A	E	V	I	Q	I	Q	A	Q	R	L	Q
Query Conservation							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Q	A	T	M	K	A	L	R	K	K	S	V	L	L	T
Template Known Secondary structure		S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		301	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350																.	.	.	.	.	.	.	.	.	360	.	.	.	.	.
		373	.	.	.	.	.	.		380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.
Predicted Secondary structure									.																																																																							.	.
Query SS confidence									.																																																																							.	.
Query Sequence		A	P	L	A	A	H	Y	.	G	A	E	F	A	V	Q	V	M	P	C	L	S	Q	I	G	S	G	S	L	P	V	D	R	L	P	S	A	A	L	T	F	T	P	H	D	G	R	G	S	H	L	E	S	L	A	A	R	W	R	E	L	P	V	P	V	I	G	R	I	Y	D	G	R	L	W	L	D	L	R	.	.
Query Conservation									.																																																																							.	.
Alig confidence									.																					.	.	.	.	.	.	.	.	.								.	.	.	.																				.											.	.
Template Conservation																														.	.	.	.	.	.	.	.	.								.	.	.	.																				.
Template Sequence		G	Y	L	E	Y	L	I	K	H	N	Y	G	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	.	.	.	.	.	.	.	.	.	L	T	I	T	F	S	V	.	.	.	.	P	N	K	D	V	F	Q	E	L	E	K	R	G	V	V	C	D	K	R	.	N	P	N	G	I	R	V	A	P	V	P	L
Template Known Secondary structure																			S		S	S	G	G	G	B		S		.	.	.	.	.	.	.	.	.								.	.	.	.	T	T									T	T	T							.	T	T	T					B			T	T
Template Predicted Secondary structure																														.	.	.	.	.	.	.	.	.								.	.	.	.																				.
Template SS confidence
		366	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.										.	.	.	.	.	.	400					.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.		420	.	.	.	.	.	.	.	.	.	430	.
				450	.	.	.	.	.	.	.	.	.	460	.
Predicted Secondary structure		.	.
Query SS confidence		.	.
Query Sequence		.	.	C	L	E	D	E	Q	R	F	L	E	M	L
Query Conservation		.	.
Alig confidence		.	.
Template Conservation
Template Sequence		Y	N	S	F	H	D	V	Y	K	F	T	N	L	L
Template Known Secondary structure		T
Template Predicted Secondary structure
Template SS confidence
		441	.	.	.	.	.	.	.	.	450	.	.	.	.