|   |
118 | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | E | Y | D | L | D | D | A | G | R | G | H | R | D | R | A | L | A | Q | L | L | C | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | T | G | A | E | D | A | C | I | V | N | N | N | A | A | A | V | L | L | M | L | A | A | T | A | S | G | K | E | V | V | V | S | R | G | E | L | V | E | I | G | G | A | F | R | I |
Query Conservation |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . |
|   |
|   |
|   |
|   |
|   |   |
|
|   |   |
|   |   |
|
|
|   |
|
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |
|   |   | . |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|
| . | . | . | . | . |
|   |   |
|   |
|   |   |   |
Template Sequence |   |
L | Q | Y | S | P | S | A | G | I | P | . |
E | L | L | S | W | L | K | Q | L | Q | I | K | L | H | N | P | P | T | I | H | Y | P | P | S | Q | G | Q | M | D | L | C | V | T | S | G | S | Q | Q | G | L | C | K | V | F | E | M | I | I | N | P | G | D | N | V | L | . |
. |
. |
. |
. |
L | D | E | P | A | Y | S | G | T |
Template Known Secondary structure |   |
T | S |
|
|
| T | T |
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T | T | T | S |
| G | G | G | T |
|  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  | . | . | . | . | . |  |  | S | S |
|
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
72 | . | . | . | . | . | . | . | 80 | . | |
. | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 140 | . | . | . | . | . |
  |
  |   |
187 | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | |
. | . | . | . | . | 210 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 220 | . | . | . | . | . | |
. | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | D | V | M | R | Q | A | G | C | T | L | H | E | V | G | T | T | N | . |
R | T | H | A | N | D | Y | R | Q | A | V | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | N | T | A | L | L | M | K | V | . |
H | T | S | N | Y | S | I | Q | G | F | T | K | A | I | D | E | A | E | L | V | A | L | G | K | E | L | D |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   | . |   |   |   |   |   |   |   |   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|   |   |   | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   | . |   |   |   |   |
|   |   |   |
|   |   |   |   |
Template Sequence |   |
L | Q | S | L | H | P | L | G | C | N | I | I | N | V | A | S | D | E | S | G | I | V | P | D | S | L | R | D | I | L | S | R | W | K | P | E | D | A | K | N | P | Q | K | N | T | P | K | F | L | Y | T | V | P | N | G | N | N | P | T | G | N | S | L | T | S | E | . |
R | K | K | E | I | Y | E | L | A | R | K | Y | D |
Template Known Secondary structure |   |
 |  |  |  | G | G | G | T |
|  |  |  |  |  |
|  |  | T | T |  |  |
|  |  |  |  |  |  |  |  | T | T | S |
| G | G | G | G | S |
| G | G | G |
|
|
| S |  |  |  |  |
|
| S | S |
| T | T | T |
|
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
. | . | . | . | . | . | . | . | 220 | . | . | . | . |
  |
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | P | V | V | T | D | L | G | S | G | S | L | V | D | L | S | Q | Y | G | L | P | K | E | P | M | P | Q | E | L | I | A | A | G | V | S | L | V | S | F | S | G | D | K | L | L | G | G | P | Q | A | G | I | I | V | G | K | K | E | M | I | A | R | L | Q | S | H | P | L | K | R | A | L | R | A | D | K | M | T | L | A |
Query Conservation |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
F | L | I | I | E | D | D | P | Y | Y | F | L | Q | F | N | K | F | R | V | P | T | . |
. |
. |
. |
F | L | S | M | D | V | D | G | R | V | I | R | A | D | S | F | S | I | I | S | S | G | L | R | I | G | F | L | T | G | P | K | P | L | I | E | R | V | I | L | H | I | Q | V | S | T | L | H | P | S | T | F | N | Q | L |
Template Known Secondary structure |   |
|  |  |  |  |  |
| T | T | T | T |
| B | S | S | S | S |
|
|
|
| . | . | . | . | S | G | G | G |
| S | S | S |
|  |  |  |  |  |  |
|
|
|
|
| S | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
| S | S |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
225 | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | |
|
|
|
. | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 |
  |
  |   |
333 | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | E | A | T | L | R | L | Y | L | H | P | E | A | L | S | E | K | L | P | T | L | R | L | L | T | R | S | A | E | V | I | Q | I | Q | A | Q | R | L | Q | A | P | L | A | A | H | Y | G | A | E | F | A | V | Q | V | M | P | C | L | S | Q | I | G | S | G | S | L | P | V | D | R | L | P | S | A | A | L | T | F | T |
Query Conservation |   |
  |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |
|   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
| . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|
Template Sequence |   |
M | I | S | Q | L | L | . |
. |
. |
. |
. |
. |
. |
H | E | W | G | E | E | G | F | M | A | H | V | D | R | V | I | D | F | Y | S | N | Q | K | D | A | I | L | A | A | A | D | K | W | L | T | G | L | A | E | W | H | V | P | A | A | G | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | L | W | I |
Template Known Secondary structure |   |
 |  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | B | T | T |  |  |  |
|
|
| S | B | S | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  | . | . | . | . | . | . | . |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
302 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . |
  |
  |   |
413 | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | H | D | G | R | G | S | H | L | E | S | L | A | A | R | W | R | E | L | P | V | P | V | I | G | . |
. |
. |
. |
. |
. |
. |
. |
R | I | Y | D | G | R | L | W | L | D | L | R | C | L | E | D | E | Q | R | F | L | E | M | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|   |   | . | . | . | . | . | . | . | . |
|
|   |   |   |   |
|   |
|   |   |
|
|
|   |
|   |
|   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   | . |   |   |   |   |   |
|   |
|   |   |   |
|
Template Sequence |   |
K | V | K | G | I | N | D | V | K | E | L | I | E | E | K | A | V | K | M | G | V | L | M | L | P | G | N | A | F | Y | V | D | S | S | A | P | S | P | Y | L | R | A | S | F | . |
S | S | A | S | P | E | Q | M | D | V | A | F |
Template Known Secondary structure |   |
 |  | T | T |
| S |
| S |  |  |  |  |  | T |  |  |  |  | T | T |
|
|
|  |  | G | G | G | G | S | S | S | T | T | S |
|
|
|  |  |  |  |  |
| . | S | S |
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
359 | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | |
. | . | . | . | . | . | . | 410 | . | . | . | . |
  |