|   |
38 | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | L | L | R | Q | M | L | D | E | A | R | E | V | I | R | G | S | Q | T | L | P | A | W | C | E | N | W | A | Q | E | V | D | A | R | L | T | K | E | A | Q | S | A | L | R | P | V | I | N | L | T | G | T | V | L | . |
. |
. |
. |
. |
. |
H | T | N | L | G | R | A | L | Q | A | E | A | A | V | E | A | V | A | Q | A |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   | . | . | . | . | . | . |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |
|   |   |   |   |   |
|   |
|   |   |   |   |
|   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|
|
|   |   | . | . |
|   |
|   |   |
|   |   |   |   |
Template Sequence |   |
E | K | S | K | T | A | F | K | E | A | Q | K | L | M | P | G | G | V | N | S | P | V | R | A | F | K | S | V | D | M | . |
D | P | I | F | M | E | R | G | K | G | S | K | I | F | D | I | D | G | N | E | Y | I | D | Y | V | L | S | W | G | P | L | I | L | G | H | T | N | . |
. |
D | R | V | V | E | S | L | K | K | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | T | S | G | G | G | S | S | S | G | G | G | G |
| T | T | T | T | S | . |
|
|
|
|  |  |  |  |  | B | T |  |  |  |  | T | T |
|
|  |  |  |  | S | S | G | G | G | T | T |
| T | T |
| B | S |
| . | . |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | |
. | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | |
|
. | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
112 | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | |
. | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | |
|
|
. | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | |
|
|
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
M | R | S | P | V | T | L | E | Y | D | L | D | D | A | G | R | G | H | R | D | R | A | L | A | Q | L | L | C | R | I | T | G | . |
A | E | D | A | C | I | V | N | N | N | A | A | A | V | L | L | M | L | A | A | T | . |
. |
. |
A | S | G | K | E | V | V | V | S | R | G | E | L | V | E | I | G | G | A | F | . |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
| . |   |
|   |
|   |
|   |   |
|
|   |   |
|   |   |
|
|
|   |
|
| . | . | . |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|   |   |   |
|
|
|   |
|   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |
|
|
|   |   |   |   |   |
|   |   |
Template Sequence |   |
A | E | Y | G | T | S | F | . |
. |
. |
. |
. |
. |
G | A | P | T | E | V | E | N | E | L | A | K | L | V | I | D | R | V | P | S | V | E | I | V | R | M | V | S | S | G | T | E | A | T | M | S | A | L | R | L | A | R | G | Y | T | G | R | N | K | I | L | K | F | E | G | C | Y | H | G | H | G | D | S | L | L | I | K |
Template Known Secondary structure |   |
 |  |  |
| S |
|
| . | . | . | . | . | . | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |
| S |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  | T |
|
|
|
| S |
| G | G | G |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | |
|
|
|
|
|
. | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | I | P | D | V | M | R | Q | A | G | C | T | L | H | E | V | G | T | T | N | R | T | H | A | N | D | Y | R | Q | A | V | N | E | N | T | A | L | L | M | K | V | H | T | S | N | Y | S | I | Q | G | F | T | K | A | I | D | E | A | E | L | V | A | L | G | K | E | L | D | V |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |
Template Sequence |   |
A | G | S | G | V | A | T | L | G | L | P | D | S | P | G | V | P | E | G | I | A | K | N | T | I | T | V | P | Y | N | D | L | E | S | V | K | L | A | F | Q | Q | F | G | E | D | I | A | G | V | I | V | E | P | V | A | G | N | M | G | V | V | P | P | Q | E | G | F | L | Q | G | L | R | D | I | T | E | Q | Y | G | S |
Template Known Secondary structure |   |
|
| S | S | S | S |
| B |
|  |  | S | S | T | T |
|
| T | T | S | S | T | T |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  | G | G | G |  |  |  |  |  |  |
| S | S | B |
| S | S | S |
| B |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
156 | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . |
  |
  |   |
254 | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | |
|
|
. | 320 | . | . | . | . | . | . | . | . | . | 330 |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | V | V | T | D | L | G | S | G | S | L | V | D | L | S | Q | Y | G | L | P | K | E | P | M | P | Q | E | L | I | A | A | G | V | S | L | V | S | F | S | G | D | K | L | L | G | G | P | Q | A | G | I | I | V | G | K | K | E | M | I | A | R | L | Q | S | H | . |
. |
. |
P | L | K | R | A | L | R | A | D | K | M | T |
Query Conservation |   |
  |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|
|
|   |   |
|   |
|   |
|   |   |   | . | . | . | . | . | . | . |
|   |   |   |   |
|
|   |
|
|
|   |   |   |   |
|   |
|
| . |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
L | L | I | F | D | E | V | M | T | G | F | R | V | D | Y | N | C | . |
. |
. |
. |
. |
. |
. |
A | Q | G | Y | F | G | V | T | P | D | L | T | C | L | G | K | V | I | G | . |
G | G | L | P | V | G | A | Y | G | G | K | A | E | I | M | E | Q | I | A | P | S | G | P | I | Y | Q | A | G | T | L | S | G | N | P | L | A |
Template Known Secondary structure |   |
 |  |  |  |  |
| T | T | T | T | T | T | T | S | T | T |  | . | . | . | . | . | . | . |  |  |  |  | T | T |
|
|
| S |  |  |  |  |
| G | G | G | G | . | T | T | S | S |
|  |  |  |  |  |
|  |  |  |  | T | T | B | T | T | T | S | S | B |
|
|
|
| S | S | T | T |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  | . |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
236 | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
. | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . |
  |
  |   |
331 | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | A | L | E | A | T | L | R | L | Y | L | H | P | E | A | L | S | E | K | L | P | T | L | R | L | L | T | R | S | A | E | V | I | Q | I | Q | A | Q | R | L | Q | A | P | L | A | A |
Query Conservation |   |
  |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
M | T | A | G | L | E | T | L | K | Q | L | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | D | S | Y | K | N | F | I | K | K | G | D | R | L | E | E | G | I | S | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
308 | . | 310 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . |
  |