|   |
115 | . | . | . | . | 120 | . | . | . | . | . | . | . | . | |
. | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | V | T | L | E | Y | D | L | D | D | A | G | R | G | . |
H | R | D | R | A | L | A | Q | L | L | C | R | I | T | G | A | E | D | A | C | I | V | N | N | N | A | A | A | V | L | L | M | L | A | A | T | A | S | G | K | E | V | V | V | S | R | G | E | L | V | E | I | G | G | A | F | R | I | P | D | V | M | R | Q | A |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |
|   |   |   | . |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |
|   |
|   |
|   |   |
|
|   |   |
|   |   |
|
|
|   |
|
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |
|
|   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | G | A | P | G | Q | G | F | E | Y | S | R | S | G | N | P | T | R | N | C | L | E | K | A | V | A | A | L | D | G | A | K | Y | C | L | A | F | A | S | G | L | A | A | T | V | T | I | T | H | L | L | K | A | G | D | Q | I | I | C | M | D | D | V | Y | G | G | T | N | R | Y | . |
. |
F | R | Q | V | A | S | E | F |
Template Known Secondary structure |   |
| S | S | T | T |
|
|
|
| B | G | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  | T | T | S |
| T | T |
|  |  |  |  |  | S | S |
|
|  |  |  |  |  |  | . | . |  |  |  | T | G | G | G | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
49 | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | |
|
. | 120 | . | . | . | . | . | . |
  |
  |   |
194 | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | |
. | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | C | T | L | H | E | V | G | T | T | N | R | T | H | A | N | D | Y | R | Q | A | V | N | E | N | T | A | L | L | M | K | V | H | T | S | N | Y | S | I | Q | G | F | T | K | A | I | D | E | A | E | L | V | A | L | G | K | E | L | D | . |
V | P | V | V | T | D | L | G | S | G | S | L | V | D | L | S | Q | Y | G | L |
Query Conservation |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
| . |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
|
|   |
|   |   |   |
|   |   | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
| . | . | . | . |   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |
|   |   |   |
|
|
|
|   |
|   |
|   |   |   | . | . | . | . | . | . | . |
Template Sequence |   |
G | L | K | I | S | F | V | D | C | S | . |
. |
. |
K | I | K | L | L | E | A | A | I | T | P | E | T | K | L | V | W | I | E | T | P | T | N | P | T | Q | . |
. |
. |
. |
K | V | I | D | I | E | G | C | A | H | I | V | H | K | H | G | D | I | I | L | V | V | D | N | T | F | M | S | P | Y | . |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T |
|  |  |  |  |  |
|
| S | . | . | . | S |  |  |  |  |  |  |  |
|
| T | T |  |  |  |  |  |  |  | S | S |
| T | T | T |
| . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  | T | T | S | S | S |
|  |  |  |  |  |
| T | T | T |  |  |  | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |
|
| . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
129 | 130 | . | . | . | . | . | . | . | . | |
|
|
. | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | |
|
|
|
. | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | |
|
|
|
|
|
|
  |
  |   |
273 | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
|
|
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  | . | . | . | . |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | K | E | P | M | P | Q | E | L | I | A | A | G | V | S | L | V | S | F | S | G | D | K | L | L | G | G | P | Q | . |
. |
. |
. |
A | G | I | I | V | G | K | K | E | M | I | A | R | L | Q | S | H | P | L | K | R | A | L | R | A | D | K | M | T | L | A | A | L | E | A | T | L | R | L | Y | L | H | P | E | A | L | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|   |   |
|   |   |
|
|   |   | . | . | . | . |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
Template Sequence |   |
. |
. |
. |
. |
. |
F | Q | R | P | L | A | L | G | A | D | I | S | M | Y | S | A | T | K | Y | M | N | G | H | S | D | V | V | M | G | L | V | S | V | N | C | E | S | L | H | N | R | L | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | L | Q | N | S | L | G | A | V | P | S | P | I | D | C | Y |
Template Known Secondary structure |   |
. | . | . | . | . |  |
|
| T | T | T | T | T |
| S |  |  |  |  |  | T | T | T | T | T | T |
| S | S | S |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
195 | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . |
  |
  |   |
349 | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | K | L | P | T | L | R | L | L | T | R | S | A | E | V | I | Q | I | Q | A | Q | R | L | Q | A | P | L | A | A | H | Y | G | A | E | F | A | V | Q | V | M | P | C | L | S | Q | I | G | S | G | S | L | P | V | D | R | L | P | S | A | A | L | T | F | T | P | H | D | G | R | G | S | H | L | E | S | L | A | A | R | W |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
L | C | N | R | G | L | K | T | L | H | V | R | M | E | K | H | F | K | N | G | M | A | V | A | Q | F | L | E | S | N | P | W | V | . |
E | K | V | I | Y | P | G | L | P | S | H | P | Q | H | E | L | V | K | R | Q | C | T | G | C | T | G | M | V | T | F | Y | I | K | G | T | L | Q | H | A | E | I | F | L | K | N | L |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T |  | . |  |  |  |  |
| T | T | S | T | T | S | T | T |  |  |  |  |  |  |  |
| S | S |
|
| S |  |  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  | . |  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
254 | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | |
. | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . |
  |
  |   |
429 | 430 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | E | L | P | V | P | V | I | G | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | Y | D | G | R | L | W | L | D | L | R | C | L | E | D | E | Q | R | F | L | E | M | L | L | K |
Query Conservation |   |
|   |   |   |   |
|
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |
|   |
|   |   |
|
|
|   |
|   |
|   |
|
|   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|
|
|   | . |
|
|
|   |   |   |
|
|
|   |   |
|   |   |
Template Sequence |   |
K | L | F | T | L | A | E | S | L | G | G | F | E | S | L | A | E | L | P | A | I | M | T | H | A | S | V | L | K | N | D | R | D | V | L | G | I | S | D | T | L | I | R | L | S | V | . |
G | L | E | D | E | E | D | L | L | E | D | L | D | Q |
Template Known Secondary structure |   |
S | S | S |  |  |
| S |
|
| S | S | S | S |
|  |  |  |
| G | G | G | T | T | T | T | T | S |
|  |  |  |  |  |  |  | T |
|
| T | T |  |  |  |  |  |
| . |
| S | S |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  | . |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
333 | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | |
. | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . |
  |