|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | T | K | Y | A | L | V | G | D | V | G | G | T | N | A | R | L | A | L | C | D | I | A | S | G | E | I | S | Q | A | K | T | Y | S | G | L | D | Y | . |
. |
. |
. |
. |
. |
. |
. |
P | S | L | E | A | V | I | R | V | Y | L | E | E | H | K | V | E | . |
. |
. |
. |
V | K | D | G | C | I | A | I | A | C | P | I | T |
Query Conservation |   |
|   |   |
|   |
|   |
|
|
|
|
|
|   |   |
|   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |
|
|
|
|   |
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |   |   |
|
|
|   |   |
|   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
Template Sequence |   |
M | A | A | I | Y | G | G | V | E | G | G | G | T | R | S | E | V | L | L | V | S | E | D | G | K | I | L | A | E | A | D | G | L | S | T | N | H | W | L | I | G | T | D | K | C | V | E | R | I | N | E | M | V | N | R | A | K | R | K | A | G | V | D | P | L | V | P | L | R | S | L | G | L | S | L | S | G | G | D | Q |
Template Known Secondary structure |   |
T | S |
|  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T |
|
| B | S |  |  |  |  |  |  | T | T | T | T |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
69 | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | D | W | V | A | M | T | N | H | T | W | A | F | S | I | A | E | M | K | K | N | L | G | F | S | H | L | E | I | I | N | D | F | T | A | V | S | M | A | I | P | M | L | K | K | E | H | L | I | Q | F | G | G | A | E | P | V | E | G | K | P | I | A | V | Y | G | A | G | T | G | L | G | V | A | H | L | V | H | V | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
| . |
|   |
|   |
|
|   |   |   |
|   |   |   |
|   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | D | A | G | R | I | L | I | E | E | . |
. |
. |
. |
L | R | D | R | F | P | Y | L | S | E | S | . |
Y | L | I | T | T | D | A | A | G | S | I | A | T | A | T | . |
. |
. |
. |
. |
. |
. |
. |
P | D | G | G | V | V | L | I | S | G | T | G | S | N | C | R | L | I | N | P | D | G | S | E | S | G | C | G | G | W | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |  |
| T | T | S | B | S |
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | S | S |
|  |  |  |  |  |  | S | S | S |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
| . |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | |
|
|
|
. | . | . | . | . | . | . | . | . | 100 | . | |
. | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
  |
  |   |
|
|
149 | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 210 | . | . | . | . |
Predicted Secondary structure |   |
. | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
K | R | W | V | S | L | P | G | E | G | G | H | V | D | F | A | P | N | S | E | E | E | A | I | I | L | E | I | L | R | A | E | I | G | H | V | S | A | E | R | V | L | S | G | P | G | L | V | N | L | Y | R | A | I | V | K | A | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | R | L | P | E | N | L | K |
Query Conservation |   |
. | . |   |
|   |   |   |   |
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|   |
|   |   |
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
H | M | M | G | D | E | G | S | A | Y | W | I | A | H | Q | A | V | K | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | F | D | S | I | D | N | L | E | A | A | P | H | D | I | G | Y | V | K | Q | A | M | F | H | Y | F | Q | V | P | D | R | L | G | I | L | T | H | L | Y | R | D | F | D | K | C | R | F | A | G |
Template Known Secondary structure |   |
T | T | T |
|
| T | T | S |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  | T | S | S |
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  | T |
| S | S |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . |
  |
  |   |
215 | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . |  |  |  |  |  |
|  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | K | D | I | T | E | R | A | L | A | D | S | C | T | D | C | R | R | A | L | S | L | F | C | V | I | M | G | R | F | G | G | N | L | A | L | N | L | G | T | F | G | . |
. |
. |
. |
. |
. |
. |
G | V | F | I | A | G | G | I | V | P | R | F | L | E | F | F | K | A | S | G | F | R | A | A | F | E | D | K | G | R | F |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . |   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |
| . | . |   |   |   |   |   |   |   |
|   |   |   |   | . | . |
Template Sequence |   |
F | C | R | K | I | A | E | G | A | Q | Q | G | D | P | L | S | R | Y | I | F | R | K | A | G | E | M | L | G | R | H | I | V | A | V | L | P | E | I | D | P | V | L | F | Q | G | K | I | G | L | P | I | L | C | V | G | S | V | W | K | S | W | E | L | L | . |
. |
K | E | G | F | L | L | A | L | T | Q | G | R | . |
. |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | S |
| G | G | G | G |
| S | S | S |
|  |  |  |  |  |  | S | G | G | G | G | G |  |  |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|  |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
216 | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | |
|
280 | . | . | . | . | . | . | . | . | . | 290 | . | |
|
  |
  |   |
288 | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . |
Predicted Secondary structure |   |
|  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | E | Y | V | H | D | I | P | V | Y | L | I | V | H | D | N | P | G | L | L | G | S | G | A | H | L | R | Q | T | L | G | H | I | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |
|   |   |   |
|   |   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
E | I | F | S | S | F | T | L | M | K | L | R | H | S | S | A | L | G | G | A | S | L | G | A | R | H | I | G | H | L | L |
Template Known Secondary structure |   |
. | . | . |  |
|
|
|  |  |  |  |  |  |  | S | S |
| T |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|
|
Template Predicted Secondary structure |   |
. | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
292 | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
  |