|   |
18 | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | |
|
|
. | . | |
|
. | 40 | . | . | . | . | . | . | . | . | |
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
| . | . |
|
|  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
| . |
. |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | V | V | E | R | P | A | S | V | V | K | E | L | V | E | N | S | L | D | . |
. |
. |
A | G | . |
. |
A | T | R | I | D | I | D | I | E | R | . |
G | G | A | K | L | I | R | I | R | D | N | G | C | G | I | K | K | D | . |
. |
. |
. |
. |
. |
. |
. |
E | L | A | L | A | L | A | R | H | A | T | S | K | I | A | S | L |
Query Conservation |   |
|
|
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
| . | . |
|
|   |
|   |
|   |
|   |   | . |   |
|   |   |   |
|   |
|   |
|
|
|   |
|
|   |   |   | . | . | . | . | . | . | . | . |
|
|   |   |   |   |   |
|
|   |
|
|
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
| . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
Template Conservation |   |
  |   |
|   |
|
|   |   |
|   |   |
|
|
|   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |
|   |
|   |
|   |   |   |
|
|
| . | . |
|
|
|   |
|
|
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |
|
| . | . |   |
|
|
Template Sequence |   |
T | I | V | P | G | L | F | K | I | F | D | E | I | L | V | N | A | A | D | N | K | V | R | D | P | S | M | K | R | I | D | V | N | I | H | A | E | E | H | T | . |
. |
I | E | V | K | N | D | G | K | G | I | P | I | E | I | H | N | K | E | N | I | Y | I | P | E | M | I | F | G | H | L | L | T | S | . |
. |
S | N | Y |
Template Known Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  | T | T | T | T |  | . | . |  |  |  |  |  |  | S | S |
|
|
|
| S | B |
| T | T | T |
| S | B |  |  |  |  |  |  |  | S | S | S |
|
| . | . | S |
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
55 | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | |
|
. | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | |
|
. | . | 130 |
  |
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | |
. | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
|
|
. | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|  |  |
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | D | L | E | A | I | I | S | L | G | F | R | G | E | A | L | A | S | I | S | S | V | S | R | . |
L | T | L | T | S | R | T | A | E | Q | Q | E | A | W | Q | A | Y | A | E | G | R | D | M | N | V | T | V | K | P | A | A | . |
. |
. |
. |
H | P | V | G | T | T | L | E | V | L | D | L | F | Y | N | T | P | A | R | R |
Query Conservation |   |
  |
|
|   |   |
|   |
|   |
|
|
|
|
|
|
|   |
|
|   |   |
|
|   | . |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |
|
|   |
|   |
|   |   |
|
|   |
|   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |   |
|   |
|
|
|   |
|   |
|   |
|
|   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   | . | . | . | . |
|   |
|
|   |   |
|
|
Template Sequence |   |
D | D | D | E | K | K | V | T | G | G | R | N | G | Y | G | A | K | L | C | N | I | F | S | T | E | F | I | L | E | T | A | D | L | N | V | G | Q | K | Y | V | Q | K | W | E | N | N | M | S | I | C | H | P | P | K | I | T | S | Y | K | K | G | P | S | Y | T | K | V | T | . |
. |
. |
. |
F | K | P | D | L | T | R | F |
Template Known Secondary structure |   |
| T | T | S |
|
|
|
| S |
|
| S | S |
|  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  | T | T | T | T |  |  |
|
|
|  |  |  |  |
|
| S | S |
|
|  |  |  |  |  | . | . | . | . |  |  |  |
| G | G | G | G |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . |  |  |  |
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
131 | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | |
|
|
|
. | 200 | . | . | . | . | . | . |
  |
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | F | L | R | T | E | K | T | E | F | N | H | I | D | E | I | I | R | R | I | A | L | A | R | F | D | V | T | I | N | L | S | H | N | G | K | I | V | R | Q | Y | R | A | V | P | E | G | G | Q | K | E | R | R | L | G | A | I | C | G | T | A | F | L | E | Q | A | L | A | I | E | W | Q | H | G | D | L | T | L | R | G |
Query Conservation |   |
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |
|   |
|   |   | . | . |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |
|
|
|   |
Template Sequence |   |
G | M | K | E | L | D | N | D | I | L | G | V | M | R | R | R | V | Y | D | I | N | G | S | V | R | D | I | N | V | Y | L | . |
. |
N | G | K | S | L | K | I | . |
. |
. |
. |
. |
. |
. |
. |
R | N | F | K | N | Y | V | E | L | Y | L | K | S | L | I | P | T | I | L | Y | . |
E | R | I | N | N | R | W | E | V | A | F |
Template Known Secondary structure |   |
T |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |
|  |  |  |  | . | . | T | T |  |  |
|
|
| . | . | . | . | . | . | . | . |
| S |  |  |  |  |  |  | T | T | T | T | T |
|
|
| S |
|  |  | . |  |  |  |  | T | T |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . |
|
|
|  |  |  |
| . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  | . |  |
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
207 | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | |
|
. | . | 240 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | |
. | . | . | . | . | 270 | . | . | . | . | . |
  |
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 290 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | V | A | D | P | N | H | T | T | P | A | L | A | E | I | Q | Y | C | Y | V | N | G | R | M | M | R | D | . |
. |
. |
. |
. |
R | L | I | N | H | A | I | R | Q | A | C | E | D | K | L | G | A | D | Q | Q | P | . |
. |
. |
. |
. |
. |
A | F | V | L | Y | L | E | I | D |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|   |
|   |   | . | . | . | . | . |   |   |
|   |   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |
| . | . | . | . | . | . |   |   |
|
|   |
|   |   |   |
Alig confidence |   |
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|
|
|
|   |
|   |
|   |   |
|
|
|
|
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |
|
|   |   |   |   |
|
|
|
|   |
|   |   |   |
|   |   |   |
|   |
Template Sequence |   |
A | V | S | . |
. |
. |
. |
. |
. |
. |
D | I | S | F | Q | Q | I | S | F | V | N | S | I | A | T | T | M | G | G | T | H | V | N | Y | I | T | D | Q | I | V | K | K | I | S | E | I | L | K | K | V | K | S | F | Q | I | K | N | N | M | F | I | F | I | N | C | L | I | E |
Template Known Secondary structure |   |
 |  |
| . | . | . | . | . | . | . | S | S | S |
|  |  |  |  |  |  | T | T |  |  |
| T | T |
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
| S |
Template Predicted Secondary structure |   |
 |  |  | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
293 | . | . | |
|
|
|
|
|
|
. | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . |
  |