Return to main results Retrieve Phyre Job Id

Job DescriptionP09151
Confidence100.00%DateThu Jan 5 11:01:59 GMT 2012
Rank12Aligned Residues272
% Identity26%Templatec2cw6B_
PDB info PDB header:lyaseChain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria
Resolution2.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1........10.........20.........30.........40.........50.. .......60.........70.....
Predicted Secondary structure 



























.....





Query SS confidence 



















































. . . . .






















Query Sequence  MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSP. . . . . GDFESVQTIARQVKNSRVCALAR
Query Conservation 
  

 
 






 
  
   
 
 

 

  
   

  



 
 

 ..... 
 
 
  
        
 

 
Alig confidence 



















































.....






















Template Conservation 


 
 
 
 




 
          
  
   
   

  



            
                     
Template Sequence  LPKRVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIETTSFVSPKWVPQMGDHTEVLKGIQKFPGINYPVLTP
Template Known Secondary structure 

SB

TTTT
SS


TT
S




TTT
GGGTTS


TT
B



Template Predicted Secondary structure 

































Template SS confidence 















































































   2930.........40.........50.........60.........70.........80.........90.........100........
 
   76...80.........90.........100.........110.........120.........130....... ..140.........
Predicted Secondary structure 














......







Query SS confidence 





























































. . . . . .











Query Sequence  CVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVE. . . . . . FSCEDAGRTPIA
Query Conservation      


 
 


   
   
 
    

 
       
 

        
  

  
  
 ......   

  
   
Alig confidence  .









....














































......











Template Conservation  .    
  
  .... 
   
 
    
                      
  
   
  
                   
Template Sequence  . NLKGFEAAVA. . . . AGAKEVVIFGAASELFTKKNINCSIEESFQRFDAILKAAQSANISVRGYVSCALGCPYEGKISPA
Template Known Secondary structure  .S....TT
SS
TSS
TTTTT
STT
BTTTBS

Template Predicted Secondary structure  .
....



















Template SS confidence 















































































   109110........ .120.........130.........140.........150.........160.........170.........180...
 
   150.........160.........170.........180.........190.........200.........210.........220.........
Predicted Secondary structure 






























Query SS confidence 















































































Query Sequence  DLARVVEAAINAGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAM
Query Conservation   
      
   


 
 
 

 
   
  
  

  
   

    
 
  
 


 










 


  

 

Alig confidence 










































...

































Template Conservation              
 
 
 
 

 
   
  
  

  
    
... 
 
  
 


 


 

 


  


  

 

Template Sequence  KVAEVTKKFYSMGCYEISLGDTIGVGTPGIMKDMLSAVMQEVP. . . LAALAVHCHDTYGQALANTLMALQMGVSVVDSSV
Template Known Secondary structure  TT
STT



S
...GGGB
TTS
TT

BT
Template Predicted Secondary structure 













...












Template SS confidence 















































































   184.....190.........200.........210.........220...... ...230.........240.........250.........260
 
   230... ......240.........250.........260.........270.........280....
Predicted Secondary structure 



......

























Query SS confidence 



. . . . . .


















































Query Sequence  NGIG. . . . . . ERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPAN
Query Conservation   


......





 

 

  
       
  
 


  
  

  
    
      
Alig confidence 



......















....






























Template Conservation   


     





   
 
   
 ....  
     
   
  
   
           
Template Sequence  AGLGGCPYAQGASGNLATEDLVYMLE. . . . GLGIHTGVNLQKLLEAGNFICQALNRKTSSK
Template Known Secondary structure  TS



TTSSS


B
B....TT
B



T




Template Predicted Secondary structure 
















....














Template SS confidence 




























































   261........270.........280...... ...290.........300.........310.......
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions