|   |
87 | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | A | I | G | V | R | L | G | R | H | D | A | T | I | T | L | F | D | L | S | S | K | V | L | A | E | E | H | Y | P | L | P | E | R | T | Q | Q | T | L | E | H | A | L | L | N | A | I | A | Q | F | I | D | S | Y | Q | R | K | L | R | E | L | I | A | I | S | V | I | L | P | G | L | V | D | P | D | S | G | K | I | H |
Query Conservation |   |
  |   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|
|   |
|   |   |   |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|
|
|
|   |
|
|
|   |
|
|   |   |
|   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
Y | T | L | G | I | D | V | G | S | T | A | S | K | C | I | I | L | K | D | G | K | E | I | V | A | K | S | L | V | A | V | G | T | G | . |
. |
. |
. |
. |
T | S | G | P | A | R | S | I | S | E | V | L | E | N | A | H | M | K | K | E | D | M | A | F | T | L | A | T | G | Y | G | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  |
|
| S | S | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| G | G | G |
| S |  |  |  |  |  | S | T | T | T | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
  |
  |   |
167 | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | M | P | H | I | Q | V | E | N | W | G | L | V | E | A | L | E | E | R | F | K | V | T | C | F | V | G | H | D | I | R | S | L | A | L | A | E | H | Y | F | G | A | S | Q | D | C | E | D | S | I | L | V | R | V | H | R | G | T | G | A | G | I | I | S | N | G | R | I | F | I | G | R | N | G | N | V | G | E | I | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|
|   |   |
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|
|
|
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | S | L | E | G | I | A | D | K | Q | M | S | E | L | S | C | H | A | M | G | A | S | F | I | W | P | N | V | H | . |
. |
. |
T | V | I | D | I | G | G | Q | D | V | K | V | I | H | V | E | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T | T | T | T | T |
| S |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
| . | . | . |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | |
|
|
. | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
  |
  |   |
247 | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | |
|
|
|
. | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | I | Q | V | E | P | L | G | E | R | C | H | C | G | N | F | G | C | L | E | T | I | A | A | N | A | A | I | . |
. |
. |
. |
E | Q | R | V | L | N | L | L | K | Q | G | Y | Q | S | R | V | P | L | D | D | C | T | I | K | T | I | C | K | A | A | N | K | G | D | S | L | A | S | E | V | I | E | Y | V | G | R | H | L |
Query Conservation |   |
|   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |
|   |
|
|   |   |   |
|   |   |   |
| . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |
|
|   |   |   |
|   |   |   |
|
Template Sequence |   |
T | M | T | N | F | Q | M | N | D | K | C | A | A | G | T | G | R | F | L | D | V | M | A | N | I | L | E | V | K | V | S | D | L | A | E | L | G | A | K | S | T | K | R | V | A | I | S | S | T | C | T | V | F | A | E | S | E | V | I | S | Q | L | S | K | G | T | D | K | I | . |
D | I | I | A | G | I | H | R | S | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | S | S |
|
| T | T | S |  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T | T |  |  |  |  |  | T | T |
|
| S |
|
|
|
|
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
117 | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | |
. | . | . | . | 190 | . | . | . | . | . |
  |
  |   |
323 | . | . | . | . | . | . | 330 | . | . | . | . | . | |
. | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | |
380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | K | T | I | A | I | A | I | N | L | F | N | P | . |
Q | K | I | V | I | A | G | E | I | T | E | A | D | K | V | L | L | P | A | I | E | S | C | I | N | T | Q | A | L | K | A | F | R | T | N | L | P | V | V | R | S | E | L | D | . |
H | R | S | A | I | G | A | F | A | L | V | K | R | A |
Query Conservation |   |
|   |   |
|   |   |
|   |   |   |
|   |
| . |   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   | . |   |   |   |   |   |
|
|
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|   |   |   | . |   |   |   |   |   |   |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |   |
Template Sequence |   |
A | S | R | V | I | G | L | A | N | R | V | G | I | V | K | D | V | V | M | T | G | G | V | A | Q | N | . |
Y | G | V | R | G | A | L | E | E | G | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | V | E | I | K | T | S | P | L | A | Q | Y | N | G | A | L | G | A | A | L | Y | A | Y | K | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T |
|
|
| S | S |  |  |  |  | S | G | G | G | G |
| . |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
| S |
|  |  |
|
| G | G | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
196 | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | |
. | . | . | . | . | . | . | . | 230 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . |
  |