|   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | R | N | F | H | A | I | G | V | R | L | G | R | H | D | A | T | I | T | L | F | D | L | S | S | K | V | L | A | E | E | H | Y | P | L | P | E | R | T | Q | Q | T | L | E | H | A | L | L | N | A | I | A | Q | F | I | D | S | Y | Q | R | K | L | R | E | L | I | A | I | S | V | I | L | P | G | L | V | D | P | D | S |
Query Conservation |   |
  |   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|   |   |   |
|   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   | . | . | . |   |   |
|   |
|
|
|
|   |   |
|
|   |
|
|   |   |   |
Template Sequence |   |
K | Q | H | N | V | V | A | G | V | D | X | G | A | T | H | I | R | F | C | L | R | T | A | E | G | E | T | L | H | C | E | K | K | R | T | A | E | V | I | A | P | G | L | V | S | G | I | G | E | X | I | D | E | Q | L | R | R | F | N | . |
. |
. |
A | R | C | H | G | L | V | X | G | F | P | A | L | V | S | K | D | K |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . |  |  |  |  |  |  |  |  |  |  | S | S |
| B |
| T | T | S |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | |
|
|
. | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
  |
  |   |
163 | . | . | . | . | . | . | 170 | . | |
|
|
. | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | K | I | H | Y | M | P | H | I | . |
. |
. |
Q | V | E | N | W | G | L | V | E | A | L | E | E | R | F | K | V | T | C | F | V | G | H | D | I | R | S | L | A | L | A | E | H | Y | F | G | A | S | Q | D | C | E | D | S | I | L | V | R | V | H | R | G | T | G | A | G | I | I | S | N | G | R | I | F | I | G | R | N |
Query Conservation |   |
|   |
|   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|
|   |   |
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|
|   |   |
|   |
|   |   |
|   |   |   |   | . |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |   |   |
|   |   |
|   |
|   |   |
|   |   |
Template Sequence |   |
R | T | I | I | S | T | P | N | L | P | L | T | A | A | D | L | Y | D | L | A | D | K | L | E | N | T | L | N | C | P | V | E | F | S | R | D | V | N | L | Q | L | S | W | D | V | V | E | N | . |
R | L | T | Q | Q | L | V | L | A | A | Y | L | G | T | G | X | G | F | A | V | W | X | N | G | A | P | W | T | G | A | H |
Template Known Secondary structure |   |
S |
| B |
| S |
|
| S | S | S |
|
|  |  |  |  | T | T |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | T |
| T | T | S |
|  |  |  |  |  |  | S | S | S |  |  |  |  |  |  |  | T | T |  |  |  |
|
| S | S |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | |
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | N | V | G | E | I | G | H | I | Q | V | E | P | L | G | E | R | C | H | C | G | N | F | G | C | L | E | T | I | A | A | N | A | A | I | E | Q | R | V | L | N | L | L | K | Q | G | Y | Q | S | R | V | P | L | D | D | C | T | I | K | T | I | C | K | A | A | N | K | G | D | S | L | A | S | E | V | I | E | Y | V | G |
Query Conservation |   |
  |   |
|
|
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |
|   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |
Template Sequence |   |
G | V | A | G | E | E | T | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
C | S | G | X | A | L | R | R | W | Y | E | Q | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | R | N | Y | P | L | R | D | L | F | V | H | A | E | N | A | P | . |
. |
. |
. |
. |
F | V | Q | S | L | L |
Template Known Secondary structure |   |
S |
|
|
|
|
|
| S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | S |  |  |  |  |  |  |  |  | T | T | S | . | . | . | . | . | . | . | . | . | . |
|
| S | S |
| G | G | G |  |  |  |  |  | T | T |
|  | . | . | . | . | . |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 170 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 200 | . | . |
  |
  |   |
320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | |
. | . | . | . | 370 | . | . | . | . | . | . | . | . | . | |
380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | H | L | G | K | T | I | A | I | A | I | N | L | F | N | P | Q | K | I | V | I | A | G | E | I | T | E | A | D | K | V | L | L | P | A | I | E | S | C | I | N | T | Q | A | L | K | . |
A | F | R | T | N | L | P | V | V | R | S | E | L | D | . |
H | R | S | A | I | G | A | F | A | L | V | K | R | A | M | L |
Query Conservation |   |
  |   |
|
|   |   |
|   |   |
|   |   |   |
|   |
|   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |
|   |   |
|   |   |   | . |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |
|
Template Sequence |   |
E | N | A | A | R | A | I | A | T | S | I | N | L | F | D | P | D | A | V | I | L | G | G | G | V | X | D | X | P | A | F | P | R | E | T | L | V | A | X | T | Q | K | Y | L | R | R | P | L | P | H | Q | V | V | R | F | I | A | A | S | S | S | D | F | N | G | A | Q | G | A | A | I | L | A | H | Q | R | F | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |
| T | T | T | T | S | T | T |
|
|  |  |  |  |  |  |  |  |  |  | T | S |
| T | T | T | T | T | T | T |
|  |  |  |  |
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . |
  |